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Cell differentiation

Efficient derivation of functional astrocytes from human induced pluripotent stem cells (hiPSCs)

Balazs Szeky, Veronika Jurakova, Eliska Fouskova, Anita Feher, Melinda Zana, Vivien Reka Karl, Janos Farkas, Maria Bodi-Jakus, Martina Zapletalova, Shashank Pandey, Radek Kucera, Jan Lochman, Andras Dinnyes

published 04 Dec 2024

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Microgravity’s effects on miRNA-mRNA regulatory networks in a mouse model of segmental bone defects

Aarti Gautam, Nabarun Chakraborty, George Dimitrov, Allison Hoke, Stacy Ann Miller, Kevin Swift, Bintu Sowe, Carolynn Conley, Melissa A. Kacena, Rasha Hammamieh

published 02 Dec 2024

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Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn

Xiaoning Lu, Guoqing Zhang, Hao Yang, Mingzhu Shan, Xiaoxu Zhang, Yuqin Wang, Junyan Bai, Zhangyuan Pan

published 21 Nov 2024

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Mechanism of MiR-145a-3p/Runx2 pathway in dexamethasone impairment of MC3T3-E1 osteogenic capacity in mice

Hang Wu, Xinghua Liao, Tingrui Wu, Bin Xie, Sicheng Ding, Yiren Chen, Lijun Song, Bo Wei

published 19 Nov 2024

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Effect of laser photobiomodulation combined with hydroxyapatite nanoparticles on the osteogenic differentiation of mesenchymal stem cells using artificial intelligence: An in vitro study

Eloiza Leonardo de Melo, Jéssica Meirinhos Miranda, Vanessa Bastos de Souza Rolim Lima, Wyndly Daniel Cardoso Gaião, Braulio de Vilhena Amorim Tostes, Claudio Gabriel Rodrigues, Márcia Bezerra da Silva, Severino Alves Júnior, Edson Luiz Pontes Perger, Mávio Eduardo Azevedo Bispo, Marleny Elizabeth Márquez de Martínez Gerbi

published 14 Nov 2024

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Manufacturing exosomes for wound healing: Comparative analysis of culture media

Huy Hoang Dao, Thu-Huyen Nguyen, Diem Huong Hoang, Bach Duong Vu, Minh-Anh Tran, Mai Thi Le, Nhung Thi My Hoang, Anh Viet Bui, Uyen Thi Trang Than, Xuan-Hung Nguyen

published 14 Nov 2024

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Unveiling dynamic hepatocyte plasticity in HepaRG cells with a dual CYP reporter system

Riku Asano, Yohei Iizaka, Makoto Kashima, Yojiro Anzai, Shinpei Yamaguchi, Masako Tada

published 11 Nov 2024

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n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs

Yu-Chen Deng, Jen-Wei Liu, Hsiao-Chien Ting, Tzu-Chen Kuo, Chia-Hung Chiang, En-Yi Lin, Horng-Jyh Harn, Shinn-Zong Lin, Chia-Yu Chang, Tzyy-Wen Chiou

published 07 Nov 2024

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Jian-Ping Yang, Rachel Toughiri, Anshu P. Gounder, Dan Scheibe, Matt Petrus, Sarah J. Fink, Sebastien Vallee, Jon Kenniston, Nikolaos Papaioannou, Steve Langston, Narender R. Gavva, Shane R. Horman

published 06 Nov 2024

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Overcoming problematic growth phenotypes in organoids from patients with monogenic GI disease

Katlynn Bugda Gwilt, Jay R. Thiagarajah

published 04 Nov 2024

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Epac activation reduces trans-endothelial migration of undifferentiated neuroblastoma cells and cellular differentiation with a CDK inhibitor further enhances Epac effect

Rabiu Fage Inuwa, Diana Moss, John Quayle, Rasha Swadi

published 04 Nov 2024

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Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells

Rachel B. Gilmore, Dea Gorka, Christopher E. Stoddard, Pooja Sonawane, Justin Cotney, Stormy J. Chamberlain

published 01 Nov 2024

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Six3 and Six6 jointly control diverse target genes in multiple cell populations over developmental trajectories of mouse embryonic retinal progenitor cells

Alexander Ferrena, Xusheng Zhang, Rupendra Shrestha, Deyou Zheng, Wei Liu

published 24 Oct 2024

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