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Unveiling dynamic hepatocyte plasticity in HepaRG cells with a dual CYP reporter system
published 11 Nov 2024
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n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs
published 07 Nov 2024
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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease
published 06 Nov 2024
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Overcoming problematic growth phenotypes in organoids from patients with monogenic GI disease
published 04 Nov 2024
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Epac activation reduces trans-endothelial migration of undifferentiated neuroblastoma cells and cellular differentiation with a CDK inhibitor further enhances Epac effect
published 04 Nov 2024
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Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells
published 01 Nov 2024
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Six3 and Six6 jointly control diverse target genes in multiple cell populations over developmental trajectories of mouse embryonic retinal progenitor cells
published 24 Oct 2024
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Orthosilicic acid inhibits human osteoclast differentiation and bone resorption
published 15 Oct 2024
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Depot-specific mRNA expression programs in human adipocytes suggest physiological specialization via distinct developmental programs
published 14 Oct 2024
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CRISPR/Cas9 gene editing in induced pluripotent stem cells to investigate the feline hypertrophic cardiomyopathy causing MYBPC3/R820W mutation
published 10 Oct 2024
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Role of canonical and non-canonical cAMP sources in CRHR2α-dependent signaling
published 02 Oct 2024
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Simulation of cardiac arrhythmias in human induced pluripotent stem cell-derived cardiomyocytes
published 27 Sep 2024
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Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo
published 18 Sep 2024
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