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Catalysis

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Zhongjie Liang, Lianchun Li, Yuanyuan Wang, Limin Chen, Xiangqian Kong, Yao Hong, Lefu Lan, Mingyue Zheng, Cai Guang-Yang, Hong Liu, Xu Shen, Cheng Luo, Keqin Kathy Li, Kaixian Chen, Hualiang Jiang

published 24 Aug 2011

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The Evolution of Enzyme Specificity in the Metabolic Replicator Model of Prebiotic Evolution

Balázs Könnyű, Tamás Czárán

published 16 Jun 2011

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Cell-free H-cluster Synthesis and [FeFe] Hydrogenase Activation: All Five CO and CN⁻ Ligands Derive from Tyrosine

Jon M. Kuchenreuther, Simon J. George, Celestine S. Grady-Smith, Stephen P. Cramer, James R. Swartz

published 31 May 2011

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Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH Mutations in Glioblastoma

Daniel Krell, Mawuelikem Assoku, Malcolm Galloway, Paul Mulholland, Ian Tomlinson, Chiara Bardella

published 23 May 2011

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De Novo Enzyme Design Using Rosetta3

Florian Richter, Andrew Leaver-Fay, Sagar D. Khare, Sinisa Bjelic, David Baker

published 16 May 2011

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Calcium/Calmodulin Dependent Protein Kinase II Bound to NMDA Receptor 2B Subunit Exhibits Increased ATP Affinity and Attenuated Dephosphorylation

John Cheriyan, Parimal Kumar, Madhavan Mayadevi, Avadhesha Surolia, Ramakrishnapillai V. Omkumar

published 15 Mar 2011

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Discovering Conformational Sub-States Relevant to Protein Function

Arvind Ramanathan, Andrej J. Savol, Christopher J. Langmead, Pratul K. Agarwal, Chakra S. Chennubhotla

published 28 Jan 2011

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Identification of Critical Residues of the Mycobacterial Dephosphocoenzyme A Kinase by Site-Directed Mutagenesis

Guneet Walia, Komatireddy Gajendar, Avadhesha Surolia

published 11 Jan 2011

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An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

Fang Cao, Yong Chen, Tomasz Cierpicki, Yifan Liu, Venkatesha Basrur, Ming Lei, Yali Dou

published 23 Nov 2010

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New Cobalt-Mediated Radical Polymerization (CMRP) of Methyl Methacrylate Initiated by Two Single-Component Dinuclear β-Diketone Cobalt (II) Catalysts

Feng Bao, Lingling Feng, Jie Gao, Zhifang Tan, Bin Xing, Rui Ma, Chunjie Yan

published 26 Oct 2010

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Catalytic Mechanism of Cellulose Degradation by a Cellobiohydrolase, CelS

Moumita Saharay, Hong Guo, Jeremy C. Smith

published 12 Oct 2010

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Profiling of Substrate Specificity of SARS-CoV 3CL^pro

Chi-Pang Chuck, Lin-Tat Chong, Chao Chen, Hak-Fun Chow, David Chi-Cheong Wan, Kam-Bo Wong

published 06 Oct 2010

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Light Chain Separated from the Rest of the Type A Botulinum Neurotoxin Molecule Is the Most Catalytically Active Form

Nizamettin Gul, Leonard A. Smith, S. Ashraf Ahmed

published 22 Sep 2010

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