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Catalysis

Function of the Active Site Lysine Autoacetylation in Tip60 Catalysis

Chao Yang, Jiang Wu, Y. George Zheng

published 28 Mar 2012

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A Deadenylase Assay by Size-Exclusion Chromatography

Guang-Jun He, Yong-Bin Yan

published 19 Mar 2012

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Structures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit Mechanism

Wen-Chi Cheng, Yen-Fu Chen, Hung-Jung Wang, Kai-Cheng Hsu, Shuang-Chih Lin, Tzu-Jung Chen, Jinn-Moon Yang, Wen-Ching Wang

published 16 Mar 2012

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Structure and Dynamics of the G121V Dihydrofolate Reductase Mutant: Lessons from a Transition-State Inhibitor Complex

Randall V. Mauldin, Paul J. Sapienza, Chad M. Petit, Andrew L. Lee

published 13 Mar 2012

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Isolation and Characterization of EstC, a New Cold-Active Esterase from Streptomyces coelicolor A3(2)

Guillaume Brault, François Shareck, Yves Hurtubise, François Lépine, Nicolas Doucet

published 02 Mar 2012

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A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Alessio Lodola, Davide Branduardi, Marco De Vivo, Luigi Capoferri, Marco Mor, Daniele Piomelli, Andrea Cavalli

published 28 Feb 2012

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The Origin of Large Molecules in Primordial Autocatalytic Reaction Networks

Varun Giri, Sanjay Jain

published 04 Jan 2012

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Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin

Yu-Hang Zhang, Chen-Jie Zhou, Zi-Ren Zhou, Ai-Xin Song, Hong-Yu Hu

published 28 Dec 2011

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Catalytic Properties of the Isolated Diaphorase Fragment of the NAD⁺-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha

Lars Lauterbach, Zulkifli Idris, Kylie A. Vincent, Oliver Lenz

published 10 Oct 2011

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Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria

Travis J. Riedel, Lynnette C. Johnson, John Knight, Roy R. Hantgan, Ross P. Holmes, W. Todd Lowther

published 06 Oct 2011

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Determinants of Nucleotide-Binding Selectivity of Malic Enzyme

Ju-Yi Hsieh, Meng-Chun Chen, Hui-Chih Hung

published 29 Sep 2011

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Substrate Binding Process and Mechanistic Functioning of Type 1 11β-Hydroxysteroid Dehydrogenase from Enhanced Sampling Methods

Angelo D. Favia, Matteo Masetti, Maurizio Recanatini, Andrea Cavalli

published 23 Sep 2011

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Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Zhongjie Liang, Lianchun Li, Yuanyuan Wang, Limin Chen, Xiangqian Kong, Yao Hong, Lefu Lan, Mingyue Zheng, Cai Guang-Yang, Hong Liu, Xu Shen, Cheng Luo, Keqin Kathy Li, Kaixian Chen, Hualiang Jiang

published 24 Aug 2011

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