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Cardiovascular therapy

Modelling Cognitive Decline in the Hypertension in the Very Elderly Trial [HYVET] and Proposed Risk Tables for Population Use

Ruth Peters, Nigel Beckett, Robert Beardmore, Rafael Peña-Miller, Kenneth Rockwood, Arnold Mitnitski, Shahrul Mt-Isa, Christopher Bulpitt

published 26 Jul 2010

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Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) Deficient Mice Are Susceptible to Intracerebral Thrombosis and Ischemic Stroke

Peter Kraft, Tobias Schwarz, Joost C. M. Meijers, Guido Stoll, Christoph Kleinschnitz

published 19 Jul 2010

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A Novel, Single Algorithm Approach to Predict Acenocoumarol Dose Based on CYP2C9 and VKORC1 Allele Variants

Zoraida Verde, Jonatan R. Ruiz, Catalina Santiago, Beatriz Valle, Fernando Bandrés, Elpidio Calvo, Alejandro Lucía, Félix Gómez Gallego

published 18 Jun 2010

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Angiotensin I-Converting Enzyme Gln1069Arg Mutation Impairs Trafficking to the Cell Surface Resulting in Selective Denaturation of the C-Domain

Sergei M. Danilov, Sergey Kalinin, Zhenlong Chen, Elena I. Vinokour, Andrew B. Nesterovitch, David E. Schwartz, Olivier Gribouval, Marie-Claire Gubler, Richard D. Minshall

published 03 May 2010

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Association between Repeated Unpredictable Chronic Mild Stress (UCMS) Procedures with a High Fat Diet: A Model of Fluoxetine Resistance in Mice

Elsa Isingrini, Vincent Camus, Anne-Marie Le Guisquet, Maryse Pingaud, Séverine Devers, Catherine Belzung

published 28 Apr 2010

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Meta-Analysis of Combined Therapy with Angiotensin Receptor Antagonists versus ACE Inhibitors Alone in Patients with Heart Failure

Andrea Kuenzli, Heiner C. Bucher, Inder Anand, Gregory Arutiunov, Leo C. Kum, Robert McKelvie, Rizwan Afzal, Michel White, Alain J. Nordmann

published 01 Apr 2010

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Role of TGF-β1 and MAP Kinases in the Antiproliferative Effect of Aspirin in Human Vascular Smooth Muscle Cells

Santiago Redondo, Emilio Ruiz, Antonio Gordillo-Moscoso, Jorge Navarro-Dorado, Marta Ramajo, Manuel Carnero, Fernando Reguillo, Enrique Rodriguez, Teresa Tejerina

published 22 Mar 2010

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Elevated Ratio of Urinary Metabolites of Thromboxane and Prostacyclin Is Associated with Adverse Cardiovascular Events in ADAPT

Thomas J. Montine, Joshua A. Sonnen, Ginger Milne, Laura D. Baker, John C. S. Breitner

published 19 Feb 2010

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Berberine Inhibits HIV Protease Inhibitor-Induced Inflammatory Response by Modulating ER Stress Signaling Pathways in Murine Macrophages

Weibin Zha, Guang Liang, Jian Xiao, Elaine J. Studer, Phillip B. Hylemon, William M. Pandak, Jr., Guangji Wang, Xiaokun Li, Huiping Zhou

published 09 Feb 2010

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A Novel Method to Adjust Efficacy Estimates for Uptake of Other Active Treatments in Long-Term Clinical Trials

John Simes, Merryn Voysey, Rachel O'Connell, Paul Glasziou, James D. Best, Russell Scott, Christopher Pardy, Karen Byth, David R. Sullivan, Christian Ehnholm, Anthony Keech, for the FIELD Study Investigators

published 08 Jan 2010

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Dihydro-CDDO-Trifluoroethyl Amide (dh404), a Novel Nrf2 Activator, Suppresses Oxidative Stress in Cardiomyocytes

Tomonaga Ichikawa, Jinqing Li, Colin J. Meyer, Joseph S. Janicki, Mark Hannink, Taixing Cui

published 21 Dec 2009

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Financing of U.S. Biomedical Research and New Drug Approvals across Therapeutic Areas

E. Ray Dorsey, Joel P. Thompson, Melisa Carrasco, Jason de Roulet, Philip Vitticore, Sean Nicholson, S. Claiborne Johnston, Robert G. Holloway, Hamilton Moses III

published 11 Sep 2009

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Levels of C-Reactive Protein Associated with High and Very High Cardiovascular Risk Are Prevalent in Patients with Rheumatoid Arthritis

Jonathan Graf, Rebecca Scherzer, Carl Grunfeld, John Imboden

published 16 Jul 2009

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