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The hidden risks of polypharmacy: Exploring potentially inappropriate prescribing with STOPP/START criteria version 3–A cross-sectional study

Mikołaj Szoszkiewicz, Ewa Deskur-Śmielecka, Arkadiusz Styszyński, Marcel Kusyń, Kamila Krzemińska, Barbara Więckowska, Agnieszka Neumann-Podczaska, Katarzyna Wieczorowska-Tobis

published 18 Dec 2025

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Efficacy and safety of Atezolizumab plus Bevacizumab and Lenvatinib as first-line systemic therapies for hepatocellular carcinoma: A real-world study

Sangdao Boonkaya, Chidkamon Pattarawongpaiboon, Panarat Thaimai, Prooksa Ananchuensook, Supachaya Sriphoosanaphan, Suebpong Tanasanvimon, Nattaya Teeyapun, Nussara Pakvisal, Nipaporn Siripon, Sombat Treeprasertsuk, Piyawat Komolmit, Kessarin Thanapirom

published 18 Dec 2025

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Overexpression of PTPRCAP inhibits biological function of lung adenocarcinoma through apoptosis pathway

Yuting Yang, Baoshan Zhao, Yingjie Jiang, Xiaoli Han, Jingtao Huang, Guangrui Sun, Zongying Liang

published 18 Dec 2025

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Visual prediction of outcomes in patients undergoing intravenous thrombolysis

Qing Liang, Tao Qie, Yinglei Li

published 18 Dec 2025

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Agent-based modelling reveals feedback loops and non-linearity between mating system evolution and disease dynamics

Riccardo Tarantino, Francisco Garcia-Gonzalez

published 18 Dec 2025

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Impact of Metformin therapy on miR-9, miR-223, and miR-132 and inflammasome-related gen expression in obese and non-obes PCOS patients: A comparative study with healthy controls

Seyed Alireza Mirjalili, Seyed Mehdi Kalantar, Fateme Montazeri, Reyhaneh Azizi, Elham Hosseini, Fateme Zare, Samira Asgharzade, Korosh Ashrafi Dehkordi

published 18 Dec 2025

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Single-cell RNA-seq data normalization: A benchmarking study

Qinyu Ge, Yuqi Sheng, Junru Lu, Yuwei Yang, Min Pan

published 18 Dec 2025

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Landscape associations and population genetics of a generalist carnivore at a range limit

Bailey A. Kleeberg, Robert C. Lonsinger, Jennifer R. Adams, Lisette P. Waits, W. Sue Fairbanks

published 18 Dec 2025

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The use of social media as an influence on vaccination rates: A systematic review protocol

Juliana Iscarlaty Freire de Araújo, Francisco de Assis Moura Batista, Marilia Rute De Souto Medeiros, Bárbara de Oliveira Sena, José Adailton da Silva, Fábia Barbosa de Andrade

published 18 Dec 2025

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Genomic and enzymatic insights into α-amylase-producing Bacillus spizizenii strains isolated from Isfahan province, Iran

Batoul Al Sharif, Mohammad Mehdi Golchini, Aboozar Soorni, Rahim Mehrabi

published 18 Dec 2025

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Assessing fish welfare in small-scale commercial fixed-net fisheries off the Southern Portuguese coast

Vighnesh Samel, Rita A. Costa, Ana Marçalo, Magda Frade, Luís Bentes, João L. Saraiva, Jorge M.S. Gonçalves, Pedro M. Guerreiro

published 18 Dec 2025

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The effect of the modifiable areal unit problem on ecological model inference: A graphical simulation study for disease mapping in Australia

James Hogg, Aiden Price, Conor Hassan, Shovanur Haque, Farzana Jahan, Wala Areed, Jessica Cameron, Susanna Cramb, Helen Thompson

published 18 Dec 2025

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A qualitative exploration of the experience of individual-level stigma among adolescents with a chronic illness

Joan A. Thomas, Garth Lipps

published 18 Dec 2025

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