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Bioenergetics

Computational identification of novel SIRT4 inhibitors for diabetic nephropathy using pharmacophore modeling, molecular simulations, and DFT calculations

Wenxiang He, Jianwu Chen

published 17 Nov 2025

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Metabolic remodeling and cardiac dysfunction in left ventricular noncompaction: Insights from the MYH7 Q315R model

Shinya Takarada, Yukiko Hata, Keisuke Yaku, Hironori Izumi, Kazuki Fujii, Masaaki Omura, Ichiro Takasaki, Kaori Tsuboi, Mako Okabe, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Takashi Nakagawa, Hideyuki Hasegawa, Shojiro Ichimata, Naoki Nishida, Hisashi Mori, Yuko Yanagibashi, Keizo Takao, Fukiko Ichida, Keiichi Hirono

published 14 Nov 2025

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Multi-omics analysis reveals metabolic regulation of phosphatidylcholine, triglycerides, phosphatidylethanolamine, and cardiolipin metabolism in mouse liver with metabolic dysfunction-associated steatotic liver disease

Hong Liang, Kang Song

published 07 Nov 2025

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Unveiling and verification of mitochondria-related genes as potential diagnostic biomarkers in ulcerative colitis based on bioinformatics analysis and experimental validation

Hongliang Chen, Ning Li, Xuerong Liu, Mingyu Ran, Xinyu Geng, Jihan Qi, Jiawei Qiu, Xueyu Cang, Shiling Huang, Yingying Tian, Ram Prasad Chaulagain, Shizhu Jin

published 04 Nov 2025

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DNA/RNA hybrid profiling in autistic patients: A focus on mRNA and non-coding RNA variations

Leila Kianmehr, Kasra MokhtarZadeh, Zeynep Yilmaz, Hadi Darzi Ramandi, Ecmel Mehmetbeyoglu Duman, Elif Funda Sener, Serpil Taheri, Minoo Rassoulzadegan

published 03 Nov 2025

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Changes in metabolic energy measures for daily living activities and exercise in men and women following arduous activity in Antarctica

John Hattersley, C. Doug Thake, Chris Imray, Adrian J. Wilson

published 31 Oct 2025

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Eliosin-an alternative product from the HmPKD1 locus is a component of endoplasmic reticulum mitochondria membrane contact sites

Almira Kurbegovic, Virginie Lazar, Wei-Min Xu, Maya Seshan, John S. Underwood, Radmila Micanovic, Jeremy M. Pomerantz, Rajneesh Srivastava, Sarath Janga, Emma H. Doud, Sherry Clendenon, Marie Trudel, Angela Wandinger-Ness, Robert L. Bacallao

published 30 Oct 2025

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Comprehensive analysis of proline metabolizing genes reveals their functional diversification and abiotic stress response in Solanum lycopersicum

Md. Afser Rabbi, Md. Muluk Hossain, Md. Rihan Kabir Shuvo, Asifur Rob Bhuya, Ajit Ghosh

published 27 Oct 2025

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Comprehensive analysis of cuproptosis-related genes in diabetic cardiomyopathy

Jun Li, Hua Zhang, Xinyue Duan, Meina Zhang, Xin Li, Chunyan Hao

published 27 Oct 2025

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Molecular consequences of mitochondrial replacement may be masked from organismal traits in Tigriopus californicus

Jacob R. Denova, Ben A. Flanagan, Murad Jah, Scott L. Applebaum, Suzanne Edmands

published 24 Oct 2025

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Curated mitochondrial genome reference database of state key protected wild mammal in China

Xia Huang, Guihua Zhang, Joseph D. Orkin, Shiyun Liu, Shan Jiang, Yinhui Zhao, Pengfei Fan, Lianghua Huang, Xiaoming Zhang, Xueyou Li, Song Li, Kai He

published 23 Oct 2025

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Systemic nicotinamide mononucleotide administration to mitigate post-cardiac arrest brain injury in mice

Daiki Kaito, Tomoyoshi Tamura, Sayuri Suzuki, Ryutaro Onishi, Kenji F. Tanaka, Jun Yoshino, Tadashi Matsuoka, Katsuya Maeshima, Junichi Sasaki, Koichiro Homma

published 21 Oct 2025

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Mitochondrial dysfunction-related metabolite methylmalonic acid is associated with decreased cognitive performance

Yige Liu, Jiaxin Wang, Pengyan Wu, Fan Tang, Wanlu Guo, Ruishan Li, Xinran Wang, Yiying Zhang, Shaohong Fang

published 17 Oct 2025

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