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Biochemical analysis

Development of an optimized protocol for generating knockout cancer cell lines using the CRISPR/Cas9 system, with emphasis on transient transfection

Seyed Alireza Mousavi Kahaki, Nayereh Ebrahimzadeh, Hossein Fahimi, Arfa Moshiri

published 14 Nov 2024

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Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway

Chen Gao, Binni Yang, Yurong Li, Wenjuan Pei

published 30 Oct 2024

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‘Age specific variations in ovarian reserves in healthy fertile and infertile women: A cross sectional study

Neena Malhotra, Pankush Gupta, Saloni Kamboj, Pradeep Chaturvedi, Rintu Kutum

published 24 Oct 2024

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Development of a smartphone enabled, paper-based quantitative diagnostic assay using the HueDx color correction system

Nidhi Menon, David Beery, Prava Sharma, Adrian Crutchfield, Leah Kim, Aaron Lauer, Ayesha Azimuddin, Brianna Wronko-Stevens

published 04 Oct 2024

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In vitro 5-LOX inhibitory and antioxidant potential of isoxazole derivatives

Waqas Alam, Haroon Khan, Muhammad Saeed Jan, Hany W. Darwish, Maria Daglia, Ahmed A. Elhenawy

published 04 Oct 2024

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A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer

Jack B. Waite, RuthMabel Boytz, Alexis R. Traeger, Torrey M. Lind, Koya Lumbao-Conradson, Sharon E. Torigoe

published 30 Sep 2024

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Cytotoxicity of bendamustine, alone and in combination with novel agents, toward adult T-cell leukemia cells

Naoki Osada, Jiro Kikuchi, Yosuke Okada, Sae Matsuoka, Kazuhiro Morishita, Hideki Nakasone, Yusuke Furukawa

published 30 Sep 2024

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β-Ionone enhances the inhibitory effects of 5-fluorouracil on the proliferation of gastric adenocarcinoma cells by the GSK-3β signaling pathway

Fa-lin Wang, Xiaoxia Chang, Yuanyang Shi, Tingting Yang, Juan Li, Hongwei Dong, Qi Wang, Shujun Zhang, Jiaren Liu

published 06 Sep 2024

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The effect of ribociclib on the expression levels of miR-141 and CDK4/6-USP51 signaling pathway genes in MCF-7 and MDA-MB-231 cells

Shayeste Sadat Baghermanesh, Mahmood Barati, Arshad Hosseini

published 28 Aug 2024

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A SIRT1-independent mechanism mediates protection against steroid-induced senescence by resveralogues in equine tenocytes

Neda Heidari, Richard G. A. Faragher, Graham Pattison, Jayesh Dudhia, Roger K. W. Smith

published 22 Aug 2024

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External gas-assisted mold temperature control and optimization molding parameters for improving weld line strength in polyamide plastics

Nguyen Truong Giang, Pham Son Minh, Tran Anh Son, Van-Thuc Nguyen, Tran Minh The Uyen, Thanh Trung Do, Van Thanh Tien Nguyen

published 22 Aug 2024

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The effect of Jordanian essential oil from coriander seeds on antioxidant, anti-inflammatory, and immunostimulatory activities using RAW 246.7 murine macrophages

Amin Omar, Muna Barakat, Lujain F. Alzaghari, Shaymaa B. Abdulrazzaq, Eliza Hasen, Dinesh Kumar Chellappan, Mohammad A. A. Al-Najjar

published 06 Aug 2024

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Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights

Amanda Watson, Pankil Shah, Doug Lee, Sitai Liang, Geeta Joshi, Ediri Metitiri, Wasim H. Chowdhury, Dean Bacich, Peter Dube, Yan Xiang, Daniel Hanley, Luis Martinez-Sobrido, Ronald Rodriguez

published 02 Aug 2024

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