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Biochemical analysis

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition

Robert S. McNeill, Emily E. Stroobant, Erin Smithberger, Demitra A. Canoutas, Madison K. Butler, Abigail K. Shelton, Shrey D. Patel, Juanita C. Limas, Kasey R. Skinner, Ryan E. Bash, Ralf S. Schmid, C. Ryan Miller

published 05 Jul 2018

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Association of serum BDNF levels and the BDNF Val66Met polymorphism with the sleep pattern in healthy young adults

Kaori Saitoh, Ryuji Furihata, Yoshiyuki Kaneko, Masahiro Suzuki, Sakae Takahashi, Makoto Uchiyama

published 26 Jun 2018

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Biocompatibility and antibacterial properties of zirconium nitride coating on titanium abutments: An in vitro study

Giulia Brunello, Paola Brun, Chiara Gardin, Letizia Ferroni, Eriberto Bressan, Roberto Meneghello, Barbara Zavan, Stefano Sivolella

published 26 Jun 2018

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Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through downregulation of transforming growth factor-β1 (TGF-β1)

Jung-Pan Wang, Hsiang-Hsuan Michael Yu, En-Rung Chiang, Jir-You Wang, Po- Hsin Chou, Shih-Chieh Hung

published 26 Jun 2018

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Expression of long noncoding RNA MALAT1 correlates with increased levels of Nischarin and inhibits oncogenic cell functions in breast cancer

Steven C. Eastlack, Shengli Dong, Yin Y. Mo, Suresh K. Alahari

published 18 Jun 2018

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Leishmanicidal and fungicidal activity of lipases obtained from endophytic fungi extracts

Daniela Ribeiro Alves, Selene Maia de Morais, Fernanda Tomiotto-Pellissier, Fábio Roger Vasconcelos, Francisco das Chagas Oliveira Freire, Isaac Neto Goes da Silva, Alan Henrique Depieri Cataneo, Milena Menegazzo Miranda-Sapla, Gustavo Adolfo Saavedra Pinto, Ivete Conchon-Costa, Arlindo de Alencar Araripe Noronha, Wander Rogério Pavanelli

published 18 Jun 2018

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Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

Martin Liss, Michael H. Radke, Jamina Eckhard, Martin Neuenschwander, Vita Dauksaite, Jens-Peter von Kries, Michael Gotthardt

published 11 Jun 2018

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Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study

Yixin Liu, Heidi Kaljunen, Ana Pavić, Tuulia Saarenpää, Juha P. Himanen, Dimitar B. Nikolov, Adrian Goldman

published 11 Jun 2018

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Membrane-associated human tyrosinase is an enzymatically active monomeric glycoprotein

Nicole J. Kus, Monika B. Dolinska, Kenneth L. Young II, Emilios K. Dimitriadis, Paul T. Wingfield, Yuri V. Sergeev

published 05 Jun 2018

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New findings on SNP variants of human protein L-isoaspartyl methyltransferase that affect catalytic activity, thermal stability, and aggregation

Jeungjin Kim, Baihe Chen, Jean-Louis Bru, Eric Huynh, Mahsa Momen, Dana W. Aswad

published 01 Jun 2018

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CPR-IR is an insulin resistance index that is minimally affected by hepatic insulin clearance—A preliminary research

Tsuyoshi Okura, Risa Nakamura, Yohei Fujioka, Sonoko Kawamoto-Kitao, Yuichi Ito, Kazuhisa Matsumoto, Kyoko Shoji, Keisuke Sumi, Kazuhiko Matsuzawa, Shoichiro Izawa, Etsuko Ueta, Masahiko Kato, Takeshi Imamura, Shin-ichi Taniguchi, Kazuhiro Yamamoto

published 23 May 2018

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Endocrine disrupting potency of organic pollutant mixtures isolated from commercial fish oil evaluated in yeast-based bioassays

Marek Łukasz Roszko, Marta Kamińska, Krystyna Szymczyk, Katarzyna Piasecka-Jóźwiak, Beata Chabłowska

published 22 May 2018

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Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line

Marina García-Miguel, Jaime A. Riquelme, Ignacio Norambuena-Soto, Pablo E. Morales, Fernanda Sanhueza-Olivares, Constanza Nuñez-Soto, David Mondaca-Ruff, Nicole Cancino-Arenas, Alejandra San Martín, Mario Chiong

published 11 May 2018

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