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Biochemical analysis

Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densities

Daniel F. Clark, Rachael Schmelz, [ ... ], Kimberly R. Shorter

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

Richard L. Cullum, Lauren M. Lucas, [ ... ], David J. Riese, II

Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library

Hidenori Yano, Daisuke Nishimiya, [ ... ], Ryuji Hashimoto

Label-free hairpin-like aptamer and EIS-based practical, biostable sensor for acetamiprid detection

Jianhui Zhen, Gang Liang, Ruichun Chen, Wenshen Jia

5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems

Ce Shi, Michael P. Killoran, [ ... ], Thomas A. Kirkland

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

Xuan G. Luong, Sarah K. Stevens, [ ... ], Jerome Deval

A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction

Simon Lebek, Philipp Hegner, [ ... ], Stefan Wagner

Use of dual-flow bioreactor to develop a simplified model of nervous-cardiovascular systems crosstalk: A preliminary assessment

Nicoletta Marchesi, Annalisa Barbieri, [ ... ], Laura Calvillo

A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro

Grace L. Huang, Daniel P. Nampe, [ ... ], Han Xu

Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies

Lars Lind, Daniela Zanetti, [ ... ], Erik Ingelsson

In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer

Lisa Annabel Weber, Anne Funtan, [ ... ], Jessika-Maximiliane V. Cavalleri

Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay

Bernhard Schermer, Francesca Fabretti, [ ... ], Roman-Ulrich Müller

Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples

Nancy A. Niemuth, Thomas L. Rudge Jr., [ ... ], Carol L. Sabourin

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