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Biochemical analysis

TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-κB Dependent Induction of cFLIPL

Josep Maria Lluis, Ulrich Nachbur, Wendy Diane Cook, Ian Edward Gentle, Donia Moujalled, Maryline Moulin, Wendy Wei-Lynn Wong, Nufail Khan, Diep Chau, Bernard Andrew Callus, James Edward Vince, John Silke, David Lawrence Vaux

published 08 Jan 2010

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JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity

Nargis Nasrin, Virendar K. Kaushik, Eric Fortier, Daniel Wall, Kevin J. Pearson, Rafael de Cabo, Laura Bordone

published 22 Dec 2009

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Split-CreERT2: Temporal Control of DNA Recombination Mediated by Split-Cre Protein Fragment Complementation

Johannes Hirrlinger, Robert P. Requardt, Ulrike Winkler, Franziska Wilhelm, Christine Schulze, Petra G. Hirrlinger

published 16 Dec 2009

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A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates

Robert B. Annan, Anna Y. Lee, Ian D. Reid, Azin Sayad, Malcolm Whiteway, Michael Hallett, David Y. Thomas

published 16 Dec 2009

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Kinetic Characterization and Phosphoregulation of the Francisella tularensis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)

Safdar Jawaid, Heather Seidle, Weidong Zhou, Hafsa Abdirahman, Maher Abadeer, Joseph H. Hix, Monique L. van Hoek, Robin D. Couch

published 14 Dec 2009

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Modulation of Cell Surface Protein Free Thiols: A Potential Novel Mechanism of Action of the Sesquiterpene Lactone Parthenolide

Jolanta Skalska, Paul S. Brookes, Sergiy M. Nadtochiy, Shannon P. Hilchey, Craig T. Jordan, Monica L. Guzman, Sanjay B. Maggirwar, Margaret M. Briehl, Steven H. Bernstein

published 02 Dec 2009

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Characterization of the L-Lactate Dehydrogenase from Aggregatibacter actinomycetemcomitans

Stacie A. Brown, Marvin Whiteley

published 17 Nov 2009

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Integration of the β-Catenin-Dependent Wnt Pathway with Integrin Signaling through the Adaptor Molecule Grb2

Steve P. Crampton, Beibei Wu, Edward J. Park, Jai-Hyun Kim, Candice Solomon, Marian L. Waterman, Christopher C. W. Hughes

published 16 Nov 2009

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CD4⁺ T Cell-Derived IL-2 Signals during Early Priming Advances Primary CD8⁺ T Cell Responses

Yo-Ping Lai, Chia-Ching Lin, Wan-Jung Liao, Chih-Yung Tang, Shu-Ching Chen

published 10 Nov 2009

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Gemini, a Bifunctional Enzymatic and Fluorescent Reporter of Gene Expression

Lance Martin, Austin Che, Drew Endy

published 04 Nov 2009

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The Role of UPF0157 in the Folding of M. tuberculosis Dephosphocoenzyme A Kinase and the Regulation of the Latter by CTP

Guneet Walia, Parimal Kumar, Avadhesha Surolia

published 30 Oct 2009

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Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)

Tong Shen, Ye-Hong Kuang, Charles R. Ashby Jr, Yu Lei, Angel Chen, Ying Zhou, Xiang Chen, Amit K. Tiwari, Elizabeth Hopper-Borge, Jiangyong Ouyang, Zhe-Sheng Chen

published 20 Oct 2009

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ADP Ribosylation Factor Like 2 (Arl2) Regulates Breast Tumor Aggressivity in Immunodeficient Mice

Anne Beghin, Stéphane Belin, Rouba Hage Sleiman, Stéphanie Brunet Manquat, Sophie Goddard, Eric Tabone, Lars P. Jordheim, Isabelle Treilleux, Marie-France Poupon, Jean-Jacques Diaz, Charles Dumontet

published 15 Oct 2009

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