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Binding analysis

Biodynamics: A novel quasi-first principles theory on the fundamental mechanisms of cellular function/dysfunction and the pharmacological modulation thereof

Gianluca Selvaggio, Robert Alan Pearlstein

published 01 Nov 2018

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Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors

Nadia M. J. Rupniak, Elisabetta Perdona, Cristiana Griffante, Palmina Cavallini, Anna Sava, Daniel J. Ricca, Karl B. Thor, Edward C. Burgard, Mauro Corsi

published 25 Oct 2018

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A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins

Heidar Ali Panahi, Azam Bolhassani, Gholamreza Javadi, Zahra Noormohammadi

published 24 Oct 2018

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Bioprocess development of antibody-drug conjugate production for cancer treatment

Jianfa Ou, Yingnan Si, KahYong Goh, Norio Yasui, Yichen Guo, Jiajia Song, Lizhong Wang, Renata Jaskula-Sztul, Jinda Fan, Lufang Zhou, Runhua Liu, Xiaoguang Liu

published 23 Oct 2018

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Display of the HIV envelope protein at the yeast cell surface for immunogen development

Elizabeth Mathew, Hong Zhu, Sara M. Connelly, Mark A. Sullivan, Matthew G. Brewer, Michael S. Piepenbrink, James J. Kobie, Stephen Dewhurst, Mark E. Dumont

published 18 Oct 2018

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cGMP production of astatine-211-labeled anti-CD45 antibodies for use in allogeneic hematopoietic cell transplantation for treatment of advanced hematopoietic malignancies

Yawen Li, Donald K. Hamlin, Ming-Kuan Chyan, Roger Wong, Eric F. Dorman, Robert C. Emery, Douglas R. Woodle, Ronald L. Manger, Margaret Nartea, Aimee L. Kenoyer, Johnnie J. Orozco, Damian J. Green, Oliver W. Press, Rainer Storb, Brenda M. Sandmaier, D. Scott Wilbur

published 18 Oct 2018

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Large-scale docking predicts that sORF-encoded peptides may function through protein-peptide interactions in Arabidopsis thaliana

Rashmi R. Hazarika, Nikolina Sostaric, Yifeng Sun, Vera van Noort

published 15 Oct 2018

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Ca²⁺ binding induced sequential allosteric activation of sortase A: An example for ion-triggered conformational selection

Ilke Ugur, Martin Schatte, Antoine Marion, Manuel Glaser, Mara Boenitz-Dulat, Iris Antes

published 15 Oct 2018

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Development of novel aptamers for low-density lipoprotein particle quantification

Daniel Klapak, Sarah Broadfoot, Gregory Penner, Anup Singh, Eshwar Inapuri

published 11 Oct 2018

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Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition

Tomoya Takahashi, Satoru Nagatoishi, Daisuke Kuroda, Kouhei Tsumoto

published 11 Oct 2018

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Desmoplakin interacts with the coil 1 of different types of intermediate filament proteins and displays high affinity for assembled intermediate filaments

Bertrand Favre, Nadja Begré, Jamal-Eddine Bouameur, Prakash Lingasamy, Gloria M. Conover, Lionel Fontao, Luca Borradori

published 04 Oct 2018

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Theoretical analysis of inducer and operator binding for cyclic-AMP receptor protein mutants

Tal Einav, Julia Duque, Rob Phillips

published 26 Sep 2018

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Bayesian analysis of isothermal titration calorimetry for binding thermodynamics

Trung Hai Nguyen, Ariën S. Rustenburg, Stefan G. Krimmer, Hexi Zhang, John D. Clark, Paul A. Novick, Kim Branson, Vijay S. Pande, John D. Chodera, David D. L. Minh

published 13 Sep 2018

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