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Antigen presentation

Subgrouping breast cancer patients based on immune evasion mechanisms unravels a high involvement of transforming growth factor-beta and decoy receptor 3

Mayassa J. Bou-Dargham, Yuhang Liu, Qing-Xiang Amy Sang, Jinfeng Zhang

published 04 Dec 2018

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Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

Dina Schneidman-Duhovny, Natalia Khuri, Guang Qiang Dong, Michael B. Winter, Eric Shifrut, Nir Friedman, Charles S. Craik, Kathleen P. Pratt, Pedro Paz, Fred Aswad, Andrej Sali

published 06 Nov 2018

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A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins

Heidar Ali Panahi, Azam Bolhassani, Gholamreza Javadi, Zahra Noormohammadi

published 24 Oct 2018

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Transcriptome analyses of Atlantic salmon muscle genes induced by a DNA vaccine against salmonid alphavirus, the causative agent of salmon pancreas disease (PD)

Mehrdad Sobhkhez, Aleksei Krasnov, Børre Robertsen

published 01 Oct 2018

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A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells

Vinod Krishna, Kurtis E. Bachman

published 23 Aug 2018

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Distinct mechanisms survey the structural integrity of HLA-B*27:05 intracellularly and at the surface

Zeynep Hein, Britta Borchert, Esam Tolba Abualrous, Sebastian Springer

published 02 Aug 2018

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MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway

Kayla R. Wilson, Haiyin Liu, Geraldine Healey, Vivian Vuong, Satoshi Ishido, Marco J. Herold, Jose A. Villadangos, Justine D. Mintern

published 12 Jul 2018

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Impact of Leishmania donovani infection on the HLA I self peptide repertoire of human macrophages

Lydon Wainaina Nyambura, Saulius Jarmalavicius, Peter Walden

published 12 Jul 2018

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Computational identification, characterization and validation of potential antigenic peptide vaccines from hrHPVs E6 proteins using immunoinformatics and computational systems biology approaches

Abbas Khan, Muhammad Junaid, Aman Chandra Kaushik, Arif Ali, Syed Shujait Ali, Aamir Mehmood, Dong-Qing Wei

published 01 May 2018

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Transcriptome analysis of plasmid-induced genes sheds light on the role of type I IFN as adjuvant in DNA vaccine against infectious salmon anemia virus

Mehrdad Sobhkhez, Aleksej Krasnov, Chia Jung Chang, Børre Robertsen

published 21 Nov 2017

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Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells

Shalini Sethumadhavan, Murillo Silva, Phaethon Philbrook, Thao Nguyen, Stephen M. Hatfield, Akio Ohta, Michail V. Sitkovsky

published 20 Nov 2017

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Downregulation of TAP1 and TAP2 in early stage breast cancer

Andrea M. Henle, Aziza Nassar, Danell Puglisi-Knutson, Bahaaeldin Youssef, Keith L. Knutson

published 01 Nov 2017

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Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells

Fiona Clarke, Christine K. Jordan, Enrique Gutiérrez-Martinez, Jack A. Bibby, Cristina Sanchez-Blanco, Georgina H. Cornish, Xuezhi Dai, David J. Rawlings, Rose Zamoyska, Pierre Guermonprez, Andrew P. Cope, Harriet A. Purvis

published 17 Oct 2017

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