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Amides

Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode

Jessica Karlsson, Carmine M. Morgillo, Alessandro Deplano, Giovanni Smaldone, Emilia Pedone, F. Javier Luque, Mona Svensson, Ettore Novellino, Cenzo Congiu, Valentina Onnis, Bruno Catalanotti, Christopher J. Fowler

published 13 Nov 2015

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Biochemical Monitoring of Spinal Cord Injury by FT-IR Spectroscopy—Effects of Therapeutic Alginate Implant in Rat Models

Sandra Tamosaityte, Roberta Galli, Ortrud Uckermann, Kerim H. Sitoci-Ficici, Robert Later, Rudolf Beiermeister, Falko Doberenz, Michael Gelinsky, Elke Leipnitz, Gabriele Schackert, Edmund Koch, Valdas Sablinskas, Gerald Steiner, Matthias Kirsch

published 11 Nov 2015

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Stereochemical Control in the Still-Wittig Rearrangement Synthesis of Cyclohexyl (Z)-Alkene Inhibitors of Pin1

Xingguo R. Chen, Shuang A. Fan, Rachel I. Ware, Felicia A. Etzkorn

published 07 Oct 2015

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Effects of Very Low Dose Fast Neutrons on Cell Membrane And Secondary Protein Structure in Rat Erythrocytes

A. Saeed, Gehan A. Raouf, Sherif S. Nafee, Salem A. Shaheen, Y. Al-Hadeethi

published 05 Oct 2015

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Rosin Surfactant QRMAE Can Be Utilized as an Amorphous Aggregate Inducer: A Case Study of Mammalian Serum Albumin

Mohd Ishtikhar, Tajjali Ilm Chandel, Aamir Ahmad, Mohd Sajid Ali, Hamad A. Al-lohadan, Ayman M. Atta, Rizwan Hasan Khan

published 29 Sep 2015

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Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor

Sandra Gouveia-Figueira, Jessica Karlsson, Alessandro Deplano, Sanaz Hashemian, Mona Svensson, Marcus Fredriksson Sundbom, Cenzo Congiu, Valentina Onnis, Christopher J. Fowler

published 25 Sep 2015

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Synthesis and Evaluation of Novel Triterpene Analogues of Ursolic Acid as Potential Antidiabetic Agent

Panpan Wu, Jie Zheng, Tianming Huang, Dianmeng Li, Qingqing Hu, Anming Cheng, Zhengyun Jiang, Luoying Jiao, Suqing Zhao, Kun Zhang

published 25 Sep 2015

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Exploring Strong Interactions in Proteins with Quantum Chemistry and Examples of Their Applications in Drug Design

Neng-Zhong Xie, Qi-Shi Du, Jian-Xiu Li, Ri-Bo Huang

published 04 Sep 2015

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pH-Driven Polymorphism of Insulin Amyloid-Like Fibrils

Tomas Sneideris, Domantas Darguzis, Akvile Botyriute, Martynas Grigaliunas, Roland Winter, Vytautas Smirnovas

published 27 Aug 2015

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New Rimocidin/CE-108 Derivatives Obtained by a Crotonyl-CoA Carboxylase/Reductase Gene Disruption in Streptomyces diastaticus var. 108: Substrates for the Polyene Carboxamide Synthase PcsA

Leticia Escudero, Mahmoud Al-Refai, Cristina Nieto, Hartmut Laatsch, Francisco Malpartida, Elena M. Seco

published 18 Aug 2015

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Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels

Somayeh Mahdavi, Serdar Kuyucak

published 14 Aug 2015

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Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies

Zaman Ashraf, Abdul Bais, Md. Maniruzzaman Manir, Umar Niazi

published 12 Aug 2015

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17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting Both the Human Enzyme and Its Murine Ortholog

Emanuele M. Gargano, Giuseppe Allegretta, Enrico Perspicace, Angelo Carotti, Chris Van Koppen, Martin Frotscher, Sandrine Marchais-Oberwinkler, Rolf W. Hartmann

published 31 Jul 2015

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