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Aldosterone

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

Krister Bamberg, Ulrika Johansson, Karl Edman, Lena William-Olsson, Susanna Myhre, Anders Gunnarsson, Stefan Geschwindner, Anna Aagaard, Anna Björnson Granqvist, Frédéric Jaisser, Yufeng Huang, Kenneth L. Granberg, Rasmus Jansson-Löfmark, Judith Hartleib-Geschwindner

published 23 Feb 2018

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Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy

Ranjana Tripathi, Ryan Sullivan, Tai-Hwang M. Fan, Dong Wang, Yao Sun, Guy L. Reed, Inna P. Gladysheva

published 14 Dec 2017

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The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury

Jochen Dutzmann, Robert-Jonathan Musmann, Marco Haertlé, Jan-Marcus Daniel, Kristina Sonnenschein, Andreas Schäfer, Peter Kolkhof, Johann Bauersachs, Daniel G. Sedding

published 19 Sep 2017

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Intermediate CD14⁺⁺CD16⁺ monocytes decline after transcatheter aortic valve replacement and correlate with functional capacity and left ventricular systolic function

Jonas Neuser, Paolo Galuppo, Daniela Fraccarollo, Jens Willig, Tibor Kempf, Dominik Berliner, Johann Bauersachs, Julian Daniel Widder

published 22 Aug 2017

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Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure

Dai Suzuki, Akiko Saito-Hakoda, Ryo Ito, Kyoko Shimizu, Rehana Parvin, Hiroki Shimada, Erika Noro, Susumu Suzuki, Ikuma Fujiwara, Hiroyuki Kagechika, William E. Rainey, Shigeo Kure, Sadayoshi Ito, Atsushi Yokoyama, Akira Sugawara

published 11 Aug 2017

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Collagen turnover biomarkers and systemic right ventricle remodeling in adults with previous atrial switch procedure for transposition of the great arteries

Magdalena Lipczyńska, Piotr Szymański, Magdalena Kumor, Anna Klisiewicz, Piotr Hoffman

published 02 Aug 2017

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Diagnostic value of potassium level in a spot urine sample as an index of 24-hour urinary potassium excretion in unselected patients hospitalized in a hypertension unit

Piotr Jędrusik, Bartosz Symonides, Ewa Wojciechowska, Adam Gryglas, Zbigniew Gaciong

published 29 Jun 2017

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Bumetanide increases Cl^--dependent short-circuit current in late distal colon: Evidence for the presence of active electrogenic Cl^- absorption

Lieqi Tang, Xiefan Fang, Steven P. Winesett, Catherine Y. Cheng, Henry J. Binder, Scott A. Rivkees, Sam X. Cheng

published 02 Feb 2017

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Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury

Kai Song, Deborah Stuart, Nikita Abraham, Fei Wang, Shuping Wang, Tianxin Yang, Curt D. Sigmund, Donald E. Kohan, Nirupama Ramkumar

published 28 Jul 2016

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Exposure to an Extremely-Low-Frequency Magnetic Field Stimulates Adrenal Steroidogenesis via Inhibition of Phosphodiesterase Activity in a Mouse Adrenal Cell Line

Kazuyoshi Kitaoka, Shiyori Kawata, Tomohiro Yoshida, Fumiya Kadoriku, Mitsuo Kitamura

published 21 Apr 2016

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How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

Roy Combe, John Mudgett, Lahcen El Fertak, Marie-france Champy, Estelle Ayme-Dietrich, Benoit Petit-Demoulière, Tania Sorg, Yann Herault, Jeffrey B. Madwed, Laurent Monassier

published 18 Apr 2016

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The Early Endocrine Stress Response in Experimental Subarachnoid Hemorrhage

Christoffer Nyberg, Torbjörn Karlsson, Lars Hillered, Mats Stridsberg, Elisabeth Ronne Engström

published 23 Mar 2016

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Characterisation of Signalling by the Endogenous GPER1 (GPR30) Receptor in an Embryonic Mouse Hippocampal Cell Line (mHippoE-18)

Nicholas J. Evans, Asha L. Bayliss, Vincenzina Reale, Peter D. Evans

published 21 Mar 2016

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