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Aging

Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians

Noriyuki Fuku, Rafael Alis, [ ... ], Alejandro Lucia

Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq

Mandy Jayne Peffers, Katarzyna Goljanek-Whysall, [ ... ], Peter David Clegg

The Low Fall as a Surrogate Marker of Frailty Predicts Long-Term Mortality in Older Trauma Patients

Ting Hway Wong, Hai V. Nguyen, [ ... ], Dennis Chuen Chai Seow

The p53-Reactivating Small Molecule RITA Induces Senescence in Head and Neck Cancer Cells

Hui-Ching Chuang, Liang Peng Yang, [ ... ], Heath D. Skinner

Handgrip strength and its prognostic value for mortality in Moscow, Denmark, and England

Anna Oksuzyan, Panayotes Demakakos, [ ... ], Vladimir M. Shkolnikov

Telomere Length and Physical Performance at Older Ages: An Individual Participant Meta-Analysis

Michael P. Gardner, Carmen Martin-Ruiz, [ ... ], the Halcyon study team

Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures

Marissa J. Schafer, Igor Dolgalev, [ ... ], Stephen D. Ginsberg

Predictors of transitions in frailty severity and mortality among people aging with HIV

Thomas D. Brothers, Susan Kirkland, [ ... ], Kenneth Rockwood

Large-Scale Cortical Functional Organization and Speech Perception across the Lifespan

John P. Sheppard, Ji-Ping Wang, Patrick C. M. Wong

Prostaglandin E₂ Promotes Features of Replicative Senescence in Chronically Activated Human CD8+ T Cells

Jennifer P. Chou, Christina M. Ramirez, [ ... ], Rita B. Effros

Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina

Folami Lamoke, Sean Shaw, [ ... ], Manuela Bartoli

Enriched taxa were found among the gut microbiota of centenarians in East China

Na Wang, Rui Li, [ ... ], Qingwu Jiang

Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons

Takuto Hideyama, Sayaka Teramoto, [ ... ], Shin Kwak

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