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Addition reactions

Major Differences between Tumor and Normal Human Cell Fates after Exposure to Chemotherapeutic Monofunctional Alkylator

Maithili Gupte, Andrew N. Tuck, Vishal P. Sharma, Kandace J. Williams

Structure-Function Relationship of Substituted Bromomethylcoumarins in Nucleoside Specificity of RNA Alkylation

Stefanie Kellner, Laura Bettina Kollar, [ ... ], Mark Helm

Designed Chemical Intervention with Thiols for Prophylactic Contraception

Monika Sharma, Lokesh Kumar, [ ... ], Gopal Gupta

Re-Directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism

Rida Mourtada, Sonali B. Fonseca, [ ... ], Shana O. Kelley

Differential Targeting of Unpaired Bases within Duplex DNA by the Natural Compound Clerocidin: A Valuable Tool to Dissect DNA Secondary Structure

Matteo Nadai, Giorgio Palù, Manlio Palumbo, Sara N. Richter

DNA Polymerase α (swi7) and the Flap Endonuclease Fen1 (rad2) Act Together in the S-Phase Alkylation Damage Response in S. pombe

Milana Koulintchenko, Sonya Vengrova, [ ... ], Jacob Z. Dalgaard

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michal Bista, David Smithson, [ ... ], R. Kiplin Guy

Sulfhydryl Modification Induces Calcium Entry through IP₃-Sensitive Store-Operated Pathway in Activation-Dependent Human Neutrophils

Leiting Pan, Xian Wu, [ ... ], Jingjun Xu

An Active Site Aromatic Triad in Escherichia coli DNA Pol IV Coordinates Cell Survival and Mutagenesis in Different DNA Damaging Agents

Ryan W. Benson, Matthew D. Norton, [ ... ], Veronica G. Godoy

Alkylation of the Tumor Suppressor PTEN Activates Akt and β-Catenin Signaling: A Mechanism Linking Inflammation and Oxidative Stress with Cancer

Tracy M. Covey, Kornelia Edes, [ ... ], Frank A. Fitzpatrick

Growth Arrest of BCR-ABL Positive Cells with a Sequence-Specific Polyamide-Chlorambucil Conjugate

C. James Chou, Thomas O'Hare, [ ... ], Joel M. Gottesfeld

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