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Editorial Note

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Editorial Note: In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors

  • The PLOS One Editors

The PLOS One Editors issue this Editorial Note to inform readers that works cited in this article [1] as References 14, 33, 54, and 60 were retracted after the article’s publication date. PLOS considers that these references are not crucial in supporting the research or conclusions reported in [1], but the following sentences in the Discussion section are no longer supported:

  • The sixth sentence of the second paragraph: In ovarian carcinoma, Li et al. identified reduced WDFY3-AS2 expression in tumor tissue compared to adjacent normal tissue.
  • The fifth and sixth sentences of the fourth paragraph: In vitro assays, demonstrated that AFAP1-AS1 knockdown resulted in reduced proliferation and invasion and increased apoptosis rates in MDA-MB-231 and BT-549 cell lines. In vivo, overexpression of AFAP1-AS1 promoted tumor growth and activated Wnt/β-catenin pathway to promote tumorigenesis and cell invasion by increasing the expression of C-myc and EMT related genes.

Reference

  1. 1. Rodrigues de Bastos D, Nagai MA. In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors. PLoS One. 2020;15(5):e0232284. pmid:32401758

Citation: The PLOS One Editors (2026) Editorial Note: In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors. PLoS One 21(9): e0357419. https://doi.org/10.1371/journal.pone.0357419

Published: September 2, 2026

Copyright: © 2026 The PLOS One Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.