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Expression of Concern

Expression of Concern: Aristolochia Manshuriensis Kom Inhibits Adipocyte Differentiation by Regulation of ERK1/2 and Akt Pathway

  • The PLOS One Editors

Following the publication of this article [1], concerns were raised regarding results presented in Fig 4. Specifically, the β-actin panels of Figs 4B, 4C, and 4D appear to partially overlap, calling into question the reliability of these panels and the quantified results associated with these panels.

The authors did not respond to the journal’s queries about these data.

In light of the concerns raised, the PLOS One Editors issue this Expression of Concern to notify readers of the above unresolved concerns and to inform readers that the results presented in Fig 4 should be interpreted with caution.

Reference

  1. 1. Kwak DH, Lee J-H, Kim T, Ahn HS, Cho W-K, Ha H, et al. Aristolochia manshuriensis Kom inhibits adipocyte differentiation by regulation of ERK1/2 and Akt pathway. PLoS One. 2012;7(11):e49530. pmid:23166699

Citation: The PLOS One Editors (2026) Expression of Concern: Aristolochia Manshuriensis Kom Inhibits Adipocyte Differentiation by Regulation of ERK1/2 and Akt Pathway. PLoS One 21(8): e0355333. https://doi.org/10.1371/journal.pone.0355333

Published: August 5, 2026

Copyright: © 2026 The PLOS One Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.