Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

  • Loading metrics

Open Access

Retraction

Retraction: Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity

  • The PLOS One Editors

After this article [1,2] was published, concerns were raised regarding Figs 1, 2, and 4. Specifically,

  • In Fig 1, when levels are adjusted to visualize the background, there appears to be a vertical discontinuity between the T143D+ and D136N/T143D- lanes.
  • In all panels of Figs 2B and 2C in [1] and [2] there appear to be multiple horizontal and vertical discontinuities, areas that appear to be discontinuous with their adjacent background regions, and multiple repetitive areas within each panel.
  • In Fig 4A, there appears to be an irregularity above the current-time output in the E129K/D136N Membrane pellet panel.

In light of the above concerns that question the reliability and integrity of the reported results and conclusions, the PLOS One Editors retract this article [1,2].

CRA, CMG, SP, MS, and AB did not agree with the retraction and stand by the article’s findings. LEZ, NJJ, and LM either did not respond directly or could not be reached.

References

  1. 1. Rodríguez-Almazán C, Zavala LE, Muñoz-Garay C, Jiménez-Juárez N, Pacheco S, Masson L, et al. RETRACTED: Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity. PLoS One. 2009;4(5):e5545. pmid:19440244
  2. 2. Rodríguez-Almazán C, Zavala LE, Muñoz-Garay C, Jiménez-Juárez N, Pacheco S, Masson L, et al. Correction: Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity. PLoS One. 2013;4(5):e5545. pmid:19440244

Citation: The PLOS One Editors (2026) Retraction: Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity. PLoS One 21(3): e0345629. https://doi.org/10.1371/journal.pone.0345629

Published: March 25, 2026

Copyright: © 2026 The PLOS One Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.