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Open Access

Retraction

Retraction: Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats

  • The PLOS One Editors

After this article [1] was published, concerns were raised regarding results presented in Figs 3 and 4.

Specifically:

  • Fig 3B of this article [1] appears to partially overlap with Fig 2q of [2], and Fig 7E of [3], despite representing different experimental conditions.
  • In Fig 4, the following lanes appear more similar than would be expected from independent results:
    • Hsp70 lanes 1 and 2
    • Hsp70 lane 3, Bax lane 4, and Bax lane 6
    • Hsp70 lanes 5 and 6
    • Bax lanes 1 and 2

The authors did not comment on the above concerns.

In light of the above concerns that question the reliability and integrity of the reported results, the PLOS One Editors retract this article.

NAM agreed with the retraction. SG, NSG, PH, MH, BK, MAA, HMA, and AHAH either did not respond directly or could not be reached.

References

  1. 1. Golbabapour S, Gwaram NS, Hassandarvish P, Hajrezaie M, Kamalidehghan B, Abdulla MA, et al. RETRACTED: Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats. PLoS One. 2013;8(9):e75036. pmid:24058648
  2. 2. Golbabapour S, Gwaram NS, Al-Obaidi MMJ, Soleimani AF, Ali HM, Abdul Majid N. Schiff base metal derivatives enhance the expression of HSP70 and suppress BAX proteins in prevention of acute gastric lesion. Biomed Res Int. 2013;2013:703626. pmid:24298554
  3. 3. Moghadamtousi SZ, Rouhollahi E, Karimian H, Fadaeinasab M, Abdulla MA, Kadir HA. Gastroprotective activity of Annona muricata leaves against ethanol-induced gastric injury in rats via Hsp70/Bax involvement. Drug Des Devel Ther. 2014;8:2099–110. pmid:25378912

Citation: The PLOS One Editors (2026) Retraction: Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats. PLoS One 21(1): e0341791. https://doi.org/10.1371/journal.pone.0341791

Published: January 28, 2026

Copyright: © 2026 The PLOS One Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.