Figures
Abstract
Background
Massive irreparable rotator cuff tears (MIRCTs) present challenges in terms of traditional treatments and can result in pain and functional impairment. Due to the limitations of traditional treatments for MIRCTs, alternative options such as superior fulcrum reconstruction (SFR) using the autologous peroneus longus tendon (PLT) have been explored. This study aims to evaluate the clinical and radiographic outcomes of SFR with autologous PLT grafts for the treatment of MIRCTs after a minimum follow-up period of 1 year.
Methods
This was a prospective cohort study. Thirty-six patients with MIRCTs who underwent arthroscopic SFR with PLT grafts were enrolled and prospectively followed for a minimum of 1 year. Clinical and radiographic evaluations were performed preoperatively and at 3, 6, and 12 months postoperatively. Follow-up evaluations included assessments using the American Shoulder and Elbow Surgeons (ASES) score, Subjective Shoulder Value (SSV), visual analog scale (VAS), Quick-Disabilities of the Arm, Shoulder, and Hand (DASH) score, and measurements of shoulder joint range of motion. Radiography and MRI were used to evaluate the acromiohumeral distance (AHD), Hamada grade, and graft integrity. Repeated measures ANOVA was used to analyze the within-group and between-group differences under different conditions, followed by Bonferroni post-hoc tests to compare outcomes in the postoperative alignment subgroups.
Results
At the 1-year assessment (n = 36), 34 patients (94.4%) healed well and 2 (5.6%) had MRI-confirmed graft failure. Significant improvements were observed in ASES, QuickDASH, SSV, VAS, forward flexion, external rotation, internal rotation, and AHD scores (all P < 0.05). The use of autologous PLT grafts in SFR resulted in favorable functional outcomes, with a high graft healing rate at the 1-year follow-up.
Citation: Wang K, Peng C, Kong L, Ning R, Zhu Z, Wang J, et al. (2025) Autologous peroneus longus tendon graft for superior fulcrum reconstruction: Maintained prospective 1-year outcomes at short-term final follow-up. PLoS One 20(12): e0336413. https://doi.org/10.1371/journal.pone.0336413
Editor: Ismail Tawfeek Abdelaziz Badr, Menoufia University, EGYPT
Received: November 27, 2024; Accepted: October 25, 2025; Published: December 22, 2025
Copyright: © 2025 Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: The data underlying this study contain potentially identifying and sensitive patient clinical information. In accordance with the Internal Data Security Regulations of the Third Affiliated Hospital of Anhui Medical University (Hefei First People’s Hospital) and the confidentiality requirements of the Ethics Committee of the Third Affiliated Hospital of Anhui Medical University (Hefei First People’s Hospital), the raw individual-level datasets cannot be made publicly available. De-identified data may be made available to qualified researchers who submit a reasonable request and obtain approval from the Ethics Committee of the Third Affiliated Hospital of Anhui Medical University (Hefei First People’s Hospital). Data access requests should be directed to the Ethics Committee of the Third Affiliated Hospital of Anhui Medical University (Hefei First People’s Hospital) (contact: Ms. Xinyue Zhang, Ethics Committee Secretary; Email: 2441128528@qq.com; Tel: +86-0551-62189009). This is an independent institutional body responsible for reviewing data access applications and ensuring compliance with local regulations and patient privacy protections. The corresponding author (RN) may assist in facilitating communication with the Ethics Committee but is not involved in the decision-making process regarding data access.
Funding: This work was supported by the Anhui Provincial Key Research and Development Plan (No: 202104j07020057).
Competing interests: The authors declare that they have no competing interests.
Introduction
Massive rotator cuff tear refers to a defect larger than 5 cm or that affects at least two rotator cuff tendons. When such a tear cannot be completely repaired due to tendon retraction, fat infiltration, or muscle atrophy, it is classified as a massive irreparable rotator cuff tear (MIRCT) [1]. MIRCTs are frequently associated with significant pain and result in functional impairment. This is primarily attributed to complications, including irreversible tendon retraction, fatty infiltration, and muscle atrophy, which pose significant challenges in treatment [2,3]. Traditional treatment approaches encounter various issues, such as a partial repair re-tear rate reaching as high as 60%–80% [4]. Consequently, reverse shoulder arthroplasty is typically reserved for older patients with reduced shoulder movement demand [5–7].
The introduction of the superior capsular reconstruction (SCR) procedure has garnered considerable interest as an approach for managing MIRCTs. This innovative technique employs either fascia lata autografts (FLAs) or human dermis autografts (HDAs) to reconstruct the superior capsule [8]. Its primary objective is to prevent the excessive upward movement of the humeral head during arm elevation, thereby mitigating pain and enhancing shoulder mobility. However, this approach has some limitations, including long-term creep of the FLA [9,10], uncertain healing rates with HDAs [11], and potential complications at the donor site [12,13].
Due to its good strength and sufficient size, the peroneus longus tendon (PLT) has been used as a reconstruction material for the cruciate ligament, medial patellofemoral ligament, lateral ankle ligament, and deltoid ligament [14–18]. PLTs have a favorable track record in ligament reconstruction and are known for their significant clinical efficacy, excellent tensile strength, and commendable tendon-to-bone healing rates [17]. In 2023, Ning et al introduced a surgical technique for superior fulcrum reconstruction (SFR) using an autologous PLT to treat MIRCTs[14]. Additionally, they employed an innovative surgical approach by replacing the traditional anchor method with a bone tunnel fixation method to create a mesh-like structure in the glenohumeral joint (Fig 1). This alteration enhances the interface area between the tendon and bone, thereby reducing the risk of fixation loosening. Given the potential advantages of this technique, our primary hypothesis was that, following a minimum 1-year follow-up, we could ensure the integrity of the graft and achieve satisfactory outcome. Therefore, this study aimed to comprehensively assess both the clinical and radiographic results in patients undergoing SFR.
A, Bone tunnels; B, Schematic of tendon placement; C, Top view of the tendon placement schema.
Materials and methods
This prospective cohort study enrolled patients from February 10, 2020 to June 27, 2023 with institutional review board approval. All participants provided written informed consent. Eligibility for unilateral SFR surgery was determined by sports medicine physicians using predetermined selection criteria. The analysis included only patients who: (1) met operative indications, (2) underwent successful SFR surgery, (3) demonstrated strict adherence to standardized postoperative rehabilitation protocols, and (4) completed scheduled follow-up assessments at 3 months, 6 months, and 1 year postoperatively. Written informed consent was obtained from all participants. The study protocol was approved by the Hefei First People’s Hospital Ethics Committee (Approval No. 2020-020-02). Signed consent documents are stored securely.
Patient selection was based on the presence of symptomatic MIRCTs, defined in this study as having ≥2 tendon tears (including the supraspinatus) or a tear of at least 5 cm in the supraspinatus, where the tear could not be completely repaired, and no observed functional impairments in the deltoid, latissimus dorsi, or pectoralis major muscles. Patients with a Hamada classification of 4 or 5, those who had received an intra-articular corticosteroid injection within the month before surgery, and those with glenohumeral arthritis, a labral injury, a history of a previous shoulder cuff repair surgery, pseudoparalysis, or a shoulder infection were excluded [19,20]. Repairable tears of the infraspinatus or subscapularis were all repaired during surgery; otherwise, patients were excluded from the study. The SFR procedure was only performed on symptomatic individuals with MIRCTs who met all inclusion criteria.
Surgical technique
Each procedure was performed by an experienced surgeon. Patients were positioned in a beach chair setup under general anesthesia, and important anatomical points such as the clavicle, acromion, humeral head, and coracoid were marked with a marker. After standard sterilization and preparation, the arthroscopic tools were set up. The initial phase involved creating standard posterior viewing and anterior working portals, which were located just behind the acromion and in front of the coracoid. These portals allowed for arthroscopic inspections and internal assessments. After evaluating the extent of the damage, it was decided to repair both the infraspinatus and subscapularis muscles. The treatment plan for the biceps tendon—whether to sever, secure, or leave it untreated—was determined based on the patient’s age and the condition of the tendon. The arthroscope was then inserted into the subacromial area. To create a lateral anterior portal for operative access, a spinal needle was used as a guide. This portal was positioned approximately 3–4 cm from the acromion’s lateral boundary and aligned with the clavicle’s extension line. Additionally, a posterior lateral portal was created parallel to the anterior lateral portal, through which an arthroscope was inserted to examine the subacromial area. The synovial tissue within the subacromial space was then removed to expose the operation site, and standard subacromial decompression was performed. Subsequently, forceps were used to reduce torn rotator cuff tissue in order to assess the size and type of tear. Once an irreparable rotator cuff tear was confirmed, the decision was made to proceed with arthroscopic SFR surgery.
To harvest the PLT, a 1-cm-long skin incision was made 3 cm proximal to the lateral malleolus on the affected side. The PLT insertion point was then identified and isolated. Using a tendon harvester, approximately half of the PLT was harvested from the distal end towards the proximal end and divided into two equal portions. The two tendon ends were then woven with non-absorbable polyester sutures of different colors at each end for differentiation. The woven tendon had a length of 14–16 cm and a diameter of 2–4 mm (Fig 2) and was stored in saline-moistened gauze.
An extensive irreparable rotator cuff tear was arthroscopically treated (A). A tunnel was drilled from the glenoid at 10:30 to the contralateral 1:30 position (B to C), and two bone tunnels were created in the humeral head (D to E). The graft was then passed through these tunnels, forming a suture bridge inside the glenohumeral joint (F). The patient is in the beach-chair position (G), and the peroneus longus tendon serves as the graft (H). (G, glenoid; TG, tunnel in glenoid side; H, humeral head; TH, tunnel in humeral head side; S, supraspinatus tendon; PLT, peroneus longus tendon as a graft).
A tunnel was drilled into the glenoid using a 4.5 mm drill bit through the posterior lateral portal. The tunnel’s entrance and exit were positioned at the 10:30 and 1:30 directions on the glenoid, respectively. During preparation, great care was taken to avoid damaging the bone cortex above and lateral to the tunnel. Two bone tunnels, each with a diameter of 4.5 mm, were created in the humeral head using a knee joint anterior cruciate ligament locator. The locator was inserted through the posterolateral portal, aligned at the point where the humeral head’s bone meets the cartilage, and then drilled towards the lateral and anterior aspects of the upper part of the humerus. The entry points of the two bone tunnels within the joint were separated by 2 cm and converged into a single exit on the lateral aspect of the upper humerus. On the glenoid side, a BI-type needle was used to thread the PDS suture (Ethicon) through the bone tunnel, while on the humeral head side, a grasper retrieved the suture’s end from the two tunnels. The two intertwined tendons were then combined and sequentially maneuvered through tunnels on the humeral head side, the glenoid side, and back through the humeral head side. The ends of these tendons were then extracted from the humeral side, and all four braided ends were positioned within the joint cavity.
The tendons were distinguished and separated; one tendon’s ends were guided through a bone tunnel on the humeral side using a grasper, and the other tendon’s ends followed through the adjacent tunnel. This configuration emulates an intra-articular suture bridge, which enhances joint stability. Subsequently, the ends of all threads were secured at the tunnel exits on the humeral side. After all surgical instruments were removed, the incision was closed, a sterile dressing was applied, and the area was bandaged to conclude the procedure.
Rehabilitation
After the surgery, each patient’s shoulder was immobilized at 30° abduction using an abduction pillow (Table 1). Subsequently, active and passive range of motion exercises focused on the wrist and elbow joints were started within the first 2 weeks following the procedure. Isometric contraction exercises for the deltoid muscle were also initiated during this period. At six weeks post-surgery, the shoulder abduction brace was removed, and active-assisted motion exercises for the shoulder joint began. Additionally, throwing exercises were gradually introduced starting four months after the operation. Typically, normal activities could be resumed within 5–6 months after the surgery.
Functional and radiological evaluation
Postoperative follow-up assessments were conducted at 3, 6, and 12 months to evaluate clinical and imaging outcomes before and 1 year after surgery. The primary outcome measure was the American Shoulder and Elbow Surgeons (ASES) index score [21]. Secondary outcomes included: Visual Analog Scale (VAS) pain scores, Subjective Shoulder Value (SSV) scores, Quick Disabilities of the Arm, Shoulder and Hand (Quick-DASH) scores, and shoulder range of motion measurements. For range of motion assessment, measurements were performed with the patient seated using a high-precision digital limb goniometer (Delixi Group Co., Ltd.). s [22]. Outcomes were considered satisfactory when achieving a final ASES score >50 points plus ≥17-point postoperative improvement without requiring SFR graft revision [23].
Standard shoulder radiographs included preoperative and postoperative upright anteroposterior views to measure the acromiohumeral distance (AHD) and apply the Hamada classification. Preoperative MRI was used to examine the size of supraspinatus tears, including tear presence and muscle atrophy, to assess the SFR graft’s integrity and size, along with the condition of the remaining rotator cuff muscles. At 6 months and 1 year post-surgery, MRI was used for qualitative and structural evaluations of the rotator cuff tendon and to assess the integrity of the repair. The presence of a full-thickness defect within the graft was diagnosed as a graft tear. In contrast, a graft without a full-thickness defect was diagnosed as a healed graft [24]. The severity of the rotator cuff injury and the level of fatty infiltration as determined by the modified Goutallier classification [25].
Statistical analyses
Patients’ demographic and clinical data were presented as mean ± standard deviation (SD) for continuous variables and as frequencies (counts, n) for categorical variables. Group comparisons were performed using independent samples t-tests and chi-square tests, respectively. For functional and imaging indicators, all continuous variables were assessed for normality using Shapiro-Wilk tests prior to selecting parametric or nonparametric tests. Variables with p > 0.05 for normality were analyzed using repeated-measures ANOVA; otherwise, the Friedman test with Dunn-Bonferroni post hoc correction was applied. Data homogeneity of variances was confirmed via Levene’s test. A one-way ANOVA was used for comparison between the infraspinatus repair group and the intact group.
Results
Demographic characteristics
We assessed 42 patients who underwent SFR of the peroneus longus tendon. Sample size was determined through prospective power calculation and aligned with comparable arthroscopic studies [26–28]. Four patients who were unable to complete the follow-up period and two who underwent revision surgery due to infection and trauma were excluded from the study (Fig 3). All participants were followed for over 12 months, except for two cases where graft failure occurred at 4 and 11 months, leading to revision surgery. The mean follow-up was 12.8 months. The demographic data is presented in Table 2. Group comparisons for continuous and categorical variables were performed using the t-test and chi-square test, respectively. The analysis of demographic indicators revealed that for BMI, the p-value was 0.026 (< 0.05), suggesting a potentially significant difference between the groups. No statistically significant differences were found for the other variables.
Functional outcomes
This study demonstrated significant enhancements in ASES function scores, SSV scores, QuickDASH scores, VAS pain scores, FE, ER, and IR at 1-year post-surgery assessments compared with pre-surgery values (Table 3). The primary outcome measure, the ASES score, significantly increased from 51.2 ± 16.1 points preoperatively to 79.9 ± 10.4 points at the 1-year follow-up (P < 0.001). At the 1-year follow-up, 32 patients (94%) achieved both the minimal clinically important difference (MCID) and the substantial clinical benefit (SCB) for the ASES score (defined as 17.5 points). Additionally, regardless of whether infraspinatus repair was performed, favorable outcomes were observed in the ASES score, VAS pain score, SSV score, and QuickDASH score at the one-year postoperative follow-up, as well as in FE, ER and IR. In one case, the patient developed shoulder adhesion 5 months after surgery; however, satisfactory recovery of shoulder function was achieved through guided functional exercises by a rehabilitation physician.
Radiologic results
Table 5 presents the X-ray and MRI results. According to the X-ray results, the preoperative AHD averaged 5.6 mm. At 6 months postoperatively, it increased to 7.7 mm, then decreased to 7 mm at 1 year postoperatively (P ≤ 0.01). Nineteen patients had a Hamada grade 1 classification before the operation. This increased to 30 patients at 6 months postoperatively and then decreased to 25 patients at 1 year postoperatively. MRI evaluation revealed that among the remaining 34 patients, two experienced graft failure at postoperative months 4 and 11, respectively. The MRI-assessed tendon healing rate was 94%. Both patients showed a graft tear at the side of the greater tuberosity of the humerus. All other patients did not experience any significant complications, such as graft re-tear (Fig 4).
A, B: Preoperative MRI images; C, D, E, F: MRI images 3 months post-surgery, where C shows the coronal plane in the T2 phase, D is a cross-sectional MRI, E represents the coronal plane in the T1 phase, and F displays the MRI in the sagittal plane with bone tunnels indicated by arrows; G, H: MRI images 6 months post-surgery.
Discussion
This study demonstrates that arthroscopic SFR using autologous PLT grafts is safe and effective. In all 34 patients, the implanted PLT grafts remained intact with no donor-site complications observed, accompanied by significant improvements in range of motion. In contrast, Ohta et al.’s SCR study reported a 10.2% graft tear rate, 4.1% infection rate, and insufficient recovery of internal rotation strength in patients with concomitant subscapularis tendon tears [29]. Our results showed a consistent increase in ASES scores from preoperative (51.2) to 6 months (70.5) and 1 year postoperative (79.9). Similarly, Lim et al. [30] reported positive clinical outcomes with significant functional improvement and increased AHD (5.3 mm to 6.4 mm) in MIRCT patients treated with arthroscopic SCR; our study likewise observed AHD improvement from 5.6 mm preoperatively to 7.0 mm at one year postoperatively. Follow-up evaluations further confirmed the aforementioned improvements, which were evidenced by satisfactory graft healing, concomitant enhancement in functional mobility, and synchronous amelioration of imaging outcomes. However, Fried et al.’s 30-month SCR follow-up revealed only 50% return-to-work in manual laborers (60% to original positions), 47.6% sports resumption (33.3% achieving preoperative levels), a 14.8% reoperation rate, and 81.2% of non-returned workers still experiencing shoulder symptoms [31]. Ansgar Ilg et al.’s SCR study showed pain scores decreased from 4.2 to 1.0 with functional improvement at 2 years, but graft integrity was preserved in only 68.2% of cases [32], while Ferrando et al. [33] found a 25% graft failure rate in patients followed >2 years post-SCR. Additionally, animal studies by Peng et al. suggest that compared to SCR, SFR may yield superior outcomes in terms of collagen fiber maturity, fibrocartilage regeneration, and tendon regeneration [34]. Biomechanical investigations by Wang et al. further support the favorable performance of SFR [35,36]. Notably, although our results demonstrated statistically significant improvements, the clinical significance requires further validation through large-sample, multicenter studies.
The infraspinatus serves as a primary dynamic stabilizer of the shoulder joint. Multiple studies underscore the critical role of posterior rotator cuff integrity in glenohumeral function. Oh et al. [37] specifically demonstrated that repair of posterior rotator cuff tears (particularly the infraspinatus) is essential to restore normal glenohumeral kinematics in the setting of pathological kinematics.
Our study stratified patients into cohorts based on infraspinatus tear status to specifically evaluate the SFR technique’s clinical efficacy when managing shoulders with concomitant posterior cuff pathology. Crucially, the results demonstrate that SFR achieved comparable clinical outcomes irrespective of infraspinatus tear status, supporting its effectiveness in anatomically complex presentations (Table 4).
In traditional SCR surgeries, HDAs and FLAs are used for surface coverage. The advantage is that the graft area can be large enough to cover the humeral head, but the drawback is that the strength of the graft is often insufficient, which may lead to issues such as graft creep. The use of FLA for SCR surgery introduces complications related to obtaining a sufficient amount of FLA from the donor site. Generally, a graft with a thickness ranging from 6 to 8 mm is required to achieve satisfactory clinical outcomes [38,39]. Achieving a minimum thickness of 6 mm often involves folding the FLA multiple times, especially if the initial graft is thin. This requires a substantial volume of FLA that includes muscle intervals within the graft, potentially leading to postoperative pain in the thigh and other complications. On the other hand, the use of HDA in SCR surgery has its own set of complications, such as a lack of mechanical strength [8] and high re-tear rates [40] when applied in a solitary layer. Notably, Nimura et al. [41] reported that the HDA used for SCR in their study was elongated by approximately 15% compared to FLA. In the present study, while the AHD increased by 1.4 mm at the 1-year follow-up compared to preoperative measurements—currently supporting its efficacy in the short term—a gradual decline of 0.7 mm was observed relative to the 6-month postoperative values. The long-term functional implications of this reduction remain unclear. However, this technique has gained increasing traction in clinical practice. Emerging biomechanical and histological evidence, particularly highlighted in recent 2025 studies, supports its biological rationale and demonstrates promising outcomes [34–36]. Despite this potential, the follow-up period remains relatively short. Confirming long-term efficacy and functional sustainability necessitates larger, multicenter studies with extended follow-up durations. We anticipate that further investigation will provide more robust evidence regarding its long-term benefits.
One significant advantage of using tendons for reconstruction is that, compared to the surface coverage provided by HDAs and FLAs, tendons offer sufficient strength. Currently, commonly used tendons include the long head of the biceps tendon and hamstring tendons. The “Chinese Way” technique for reconstructing the superior capsule using the long head of the biceps tendon [42] requires a high level of integrity and stability of the tendon itself. In this study, 27 out of 36z patients experienced long head of the biceps lesions, indicating that the biceps tendon is not always suitable as a graft material. Additionally, it may lead to the development of a Popeye sign and pain originating from the “biceps anchor” due to proximal biceps degeneration. Using autologous hamstring tendons [43] for superior capsule reconstruction also presents issues such as stress concentration at the glenoid anchor, a smaller tendon-to-bone healing area, significant trauma from open surgery, and potential graft wastage.
In our study, we utilized the validated PLT as a graft material due to its excellent strength, which far exceeds the tension required for effectively restoring the initial vector with the humeral head and scapula [44]. Additionally, its appropriate length and autograft characteristics, along with low harvesting costs and minimal complications, were also reasons for choosing the PLT.
Additionally, PLT, as an autograft, has a higher healing potential compared to allografts. Yildiz et al. [45] conducted a study comparing the effects of autograft tension band FLA and HDA on chronic supraspinatus tendon tears in rabbits. Their findings demonstrated that rabbits treated with autografts exhibited enhanced collagen fiber density, improved alignment of collagen fibers, and reduced presence of inflammatory cells, indicating effective tendon-to-bone healing. Furthermore, in our follow-up observations, we found no significant complications associated with the procurement of PLT in patients who underwent the procedure.
The force balance of the glenohumeral joint is crucial for its stability [46]. Specifically, in the coronal plane, the combined action of the deltoid and rotator cuffs is essential for the force balance and normal functioning of the shoulder [47,48]. These muscles help maintain the rotational center and equilibrium between the upper and lower forces of the rotator cuff. Rotator cuff tears disrupt this force couple, which is essential for maintaining a stable fulcrum for shoulder movements. This disruption leads to superior migration of the humeral head, resulting in shear forces and a significant reduction in both elevation and rotational functions [21,49]. Our technique aids in reconstructing the fulcrum. Unlike SCR, which provides active contraction force, our method utilizes “suture bridge-like fixation” using bone tunnels, offers strong initial fixation, and limits superior migration during shoulder movement. This approach effectively manages pain and improves function by preserving the force couple. Consequently, it restores the fulcrum and enhances range of motion compared to traditional SCR methods.
For MIRCTs, the surgical goal is to preserve the rotational center, prevent pseudoparalysis [50], eliminate pain, and help patients return to normal life. Our surgical approach aims to restore the upper and lower force balance of the rotator cuff and stabilize the humeral head during glenohumeral abduction. We achieve this by creating a mesh structure on the humeral head and applying significant downward pressure using the high-strength PLT. This helps limit the superior translation of the humeral head, increase the AHD, restore joint function, prevent humeral head impingement, and alleviate shoulder joint pain. Additionally, the reduced distance between the humeral head and acromioclavicular joint decreases impingement of the graft tendon with the humeral head, reduces wear on the graft tendon, and prolongs its lifespan. In the transverse plane, the force balance is maintained by the anterior (subscapularis) and posterior (infraspinatus and teres minor) parts of the rotator cuff [51]. Therefore, we repaired the tears in the subscapularis and infraspinatus muscles during surgery.
Moreover, this surgical procedure is simpler and more economically advantageous than traditional SCR surgery. In addition to using autografts, it requires minimal consumables, such as anchor screws. Furthermore, unlike the balloon spacer, which tends to degrade over time [52,53], the peroneus longus tendon autograft offers a durable and enduring solution for the glenohumeral joint, eliminating concerns about biodegradation.
In this study, the graft was secured using bone tunnels, a fixation method that has shown favorable outcomes in animal experiments and biomechanical studies [54–56]. Bone tunnels provide an increased tendon-bone contact area, offering more growth bases for tendon-to-bone healing. Zeng et al. [57] demonstrated that the bone tunnel technique achieved superior tendon-bone healing for rotator cuff tears in a rabbit model compared to the conventional on-surface repair method. Zhao [58] used the Arthroscopic “Inlay” Bristow Procedure with Suture Button Fixation for the treatment of recurrent anterior glenohumeral instability, achieving good results by increasing the bone healing area to promote bone union. In reverse shoulder arthroplasty, the inlay fixation method has achieved good clinical outcomes and may also help improve long-term results [59,60]. Inlay biceps tenodesis for long head of biceps tendinopathy can also results in improved clinical outcomes [61]. Inspired by the favorable outcomes achieved with the inlay technique, this surgical approach adopts the inlay method, moving away from the traditional onlay approach of securing the graft onto the bone surface with anchors. Instead, it uses the tendon-bone tunnel (inlay) fixation technique, which promotes improved tendon-bone healing.
Additionally, this structure, designed to mimic a tension band [62], leverages the principles of tension to support early functional exercises. By applying controlled stress through the PLT on the bone tunnel during initial movements, this approach promotes tendon-to-bone healing while allowing functional exercises, ultimately contributing to improved long-term outcomes. Similarly, in SCR, four anchors secure the graft at both the glenoid and humeral head, resembling the double-row repair approach. By employing bone tunnels, our repair method aligns with the principles of the suture bridge method, which is known for its enhanced biomechanical characteristics [63,64].
In the present study, both graft failures occurred on the humeral side. One case involved a 72-year-old male with a BMI of 26.9, a dominant-side rotator cuff injury, diabetes, and a smoking habit; the graft failed at 11 months. The other case involved a 67-year-old male with diabetes and a dominant-side injury, whose graft failed 4 months postoperatively. Consistent with previous studies by our team and Lee et al. [65], humeral-side detachment remains the most frequent failure mode, with up to 80% of tears occurring at this site. This may be partly attributed to excessive tensile and shear stress concentrated at the lateral fixation point during active shoulder elevation, as the graft functions as a fulcrum over a larger motion arc relative to the glenoid side.
From a biomechanical perspective, the graft may not maintain full isometry throughout the shoulder’s range of motion. Non-isometric elongation patterns may generate uneven loading, and at specific joint angles, increased tensile force may amplify stress concentration at the humeral anchor site. In patients with impaired biological healing capacity, such as those with diabetes, this mechanically unfavorable environment may predispose the graft–bone interface to early failure.
Furthermore, epidemiological and clinical studies have demonstrated that diabetes significantly alters tendon structure and functional properties, increasing the risk of tendinopathy and rupture by over threefold compared to non-diabetic individuals [66]. Hyperglycemia-induced microvascular dysfunction triggers collagen disorganization, aberrant angiogenesis, and inflammation, ultimately impairing tendon–bone integration [67,68]. In this study, both early humeral-side failures occurred in diabetic patients, suggesting that hyperglycemia-mediated endothelial injury and reduced healing potential may have exacerbated the vulnerability of the fixation site under non-isometric stress.
Additionally, MIRCTs frequently occur in elderly patients, in whom osteoporosis is commonly present. Low bone mineral density in the greater tuberosity compromises initial anchor fixation strength and delays osseointegration. When combined with the non-isometric loading pattern and diabetes-related healing impairment, osteoporosis may further increase the risk of graft loosening or rupture.
Notably, among the 34 patients with satisfactory healing, 11 had comorbid diabetes; meanwhile, both failure cases occurred in diabetic individuals. Although this suggests a possible association, the current sample size is insufficient to confirm diabetes as an independent risk factor. Further studies incorporating biomechanical loading analysis and stratification by metabolic and bone quality status are warranted to clarify the interplay among diabetes, graft mechanics, and osteoporosis.
Looking ahead, further studies are warranted to stratify patients based on metabolic (e.g., diabetes) and skeletal (e.g., osteoporosis) conditions to identify specific clinical risk factors for graft failure. Subgroup analyses may clarify whether these comorbidities act independently or synergistically to compromise tendon–bone healing. In addition, finite element analysis could be utilized to simulate graft tension patterns across different shoulder motion angles and variable bone quality conditions. Such biomechanical modeling would help elucidate how non-isometric loading interacts with impaired biological healing capacity to influence fixation outcomes. These investigations may provide a more comprehensive mechanistic basis for optimizing surgical strategies and tailoring postoperative management in high-risk populations.
This study has the following limitations: All surgeries were performed by a single shoulder surgeon, potentially introducing single-surgeon bias that may influence outcomes due to operator-dependent factors, thereby limiting the generalizability of the findings; the patient cohort was relatively small and lacked a control group (e.g., patients undergoing arthroscopic superior capsule reconstruction), with subgroup analyses revealing underpowered subgroups; four cases lost to follow-up may have introduced selection bias; although no significant peroneus longus tendon donor-site complications or neurologic symptoms were observed, the absence of a structured assessment protocol necessitates further investigation to confirm long-term safety; additionally, the impact of graft thickness and rotator cuff tear extent on clinical outcomes was not explored, and inter-observer agreement for imaging assessments (e.g., tendon healing) remains unvalidated. Finally, despite favorable short-term outcomes, future multicenter, large-scale studies with long-term follow-up are warranted.
Conclusion
This study demonstrates that arthroscopic SFR achieved significant clinical efficacy at 1-year follow-up. The technique, supplemented with autologous peroneus longus tendon grafting, yielded high graft integration rates alongside statistically significant improvements in functional scores (ASES, SSV, QuickDASH), pain indices (VAS), and shoulder range of motion. Collectively, these outcomes validate the clinical utility of the SFR approach for managing MIRCTs.
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