Figures
The sixth author’s name is written incorrectly. The correct name is: Juan A. De-Pablo Moreno.
Fig 5 was uploaded incorrectly. Please see the correct Fig 5 here.
In order to identify the cell types, deconvolution analysis was used to estimate the proportions of a range of immune cells. Briefly, the IMMGEN dataset was used to generate a custom signature matrix for imputing cell fractions using the CIBERSORTx tool. Different cell populations were identified on days 3 and 14 (A and B). Differential expression levels of macrophage subtype-specific markers M1 (C and D) and M2 were determined by LogFC values (E and F). IMMGEN, Immunological genome project; LogFC, log fold change; rhFVIII, recombinant human factor VIII; mFcFVIII, mouse-specific Fc fusion factor VIII; NK cells, natural killer cells; Il6, interleukin 6; Il1b, interleukin 1b; Nos2, nitric oxide synthase 2; Cxcl2, C-X-C motif chemokine ligand 2; Ilr1, Interleukin 1 receptor type 1; Fcgr4, Fc gamma receptor 4; Irf4, Interferon regulatory factor 4; Pparg, peroxisome proliferator activated receptor gamma; Arg1, arginase-1; Chil3, chitinase-like protein 3; and Mmp9, matrix metalloproteinase 9.
Reference
Citation: Joseph BC, Whisenant TC, Cooke EJ, Zhou JY, Falah N, De-Pablo Moreno JA, et al. (2025) Correction: Synovial gene expression after hemarthrosis differs between FVIII-deficient mice treated with recombinant FVIII or FVIII-Fc fusion protein. PLoS One 20(9): e0331108. https://doi.org/10.1371/journal.pone.0331108
Published: September 4, 2025
Copyright: © 2025 Joseph et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.