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Open Access

Expression of Concern

Expression of Concern: Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway

  • The PLOS One Editors

After this article [1] was published, the following concerns were noted:

  • The article cited as Reference 21 was retracted after [1] was published.
  • The article does not comply with the PLOS Data Availability policy.
  • Many of the references are incomplete and do not list necessary information such as journal names.
  • PLOS has concerns about aspects of the article’s [1] authorship and peer review.

Reference 21 is replaced with [2].

The article’s Data Availability statement was incorrect and is updated to: All relevant data are available from the authors upon request.

In light of the cumulative issues, the PLOS One Editors issue this Expression of Concern.

References

  1. 1. Badshah I, Qazi NG, Ali F, Minhas AM, Alvi AM, Kandeel M, et al. Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. PLoS One. 2023;18(7):e0287517. pmid:37440558
  2. 2. Im JH, Yeo IJ, Hwang CJ, Lee KS, Hong JT. PEGylated erythropoietin protects against brain injury in the MCAO-induced stroke model by blocking NF-κB activation. Biomol Ther (Seoul). 2020;28(2):152–62. pmid:31813204

Citation: The PLOS One Editors (2025) Expression of Concern: Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. PLoS One 20(7): e0328450. https://doi.org/10.1371/journal.pone.0328450

Published: July 17, 2025

Copyright: © 2025 The PLOS One Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.