https://orcid.org/0009-0004-6780-8802
Figures
Abstract
Objectives
This study analysed the prevalence of artificially-sweetened beverages (ASB) consumption in the Thai population, and examined associations between ASB consumption and lifestyle, and nutritional and health-related behaviours.
Study Design
This study used cross-sectional design using nationally-representative data from the 2021 Health Behavior of Population Survey.
Methods
The study population was 8,155 Thai adults (age 20–64 years) who lived in an urban area and attained at least a bachelor degree education at the time of interview. Binary logistic regression was applied to investigate associations between ASB consumption and sociodemographic characteristics, lifestyle behaviors, and obesity in the study adults.
Results
The study found that participants who were overweight/obese Class 1 had 1.5 times (OR = 1.49, 95% CI 1.18–1.88) and 1.4 times (OR = 1.36, 95% CI 1.08–1.72), respectively, more likely to ASB consumption than those with normal weight. Non-smokers and those who engaged in regular physical activity were more likely to have higher ASB consumption. Participants living with one or more non-communicable disease (NCD) were more likely to be a consumer of ASB than those without a NCD (OR = 1.56, 95% CI 1.24–1.97). Some socio-demographic characteristics (e.g., sex, age, geographic area of residence, education) were also associated with ASB consumption.
Conclusions
The results suggest that government needs to develop effective communication strategies which convey accurate, clear, and concise information to consumers regarding the health effects of ASB consumption. This advice should be incorporated with interventions to improve food literacy, and in marketing control to improve individual consumption behavior and promote a healthier food environment.
Citation: Loyfah N, Chamratrithirong A, Gray RS, Pattaravanich U, Thapsuwan S, Thongcharoenchupong N, et al. (2025) Lifestyle, nutritional, and health influences on consumption of artificially-sweetened beverages in educated urban populations. PLoS One 20(4): e0322553. https://doi.org/10.1371/journal.pone.0322553
Editor: Kamal Ahmad Qureshi, Qassim University, SAUDI ARABIA
Received: May 30, 2024; Accepted: March 24, 2025; Published: April 29, 2025
Copyright: © 2025 Loyfah et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: The data that support the findings of this study were collected and managed by the National Statistical Office of Thailand (NSO). Restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available. The NSO gave the authors permission for use of this dataset. Data are available from the NSO on reasonable request and may be provided to eligible parties with the completion of any required prerequisites (such as a Data Use Agreement). To place a request for data, contact Social Statistics Division via social.group@nso.go.th. This manuscript's data is also available from the authors with approval of the NSO.
Funding: The author(s) received no specific funding for this work.
Competing interests: The authors have declared that no competing interests exist.
Introduction
In May 2023 the World Health Organization (WHO) launched new guidelines on non-sugar sweeteners (NSS), which include acesulfame K, aspartame, advantame, cyclamates, neotame, saccharin, sucralose, stevia, and other stevia derivatives [1]. The WHO recommendations point out that NSS may have undesirable health effects which include increased risks of disease, such as diabetes and cardiovascular illness. There may also be other adverse health effects such as the increased risk of premature death among adults. In addition to discouraging use of NSS, the WHO recommendations also warn against the use of all synthetic and naturally-occurring or modified non-nutritive sweeteners in manufactured foods and beverages[1].
Increased consumer health awareness and changing lifestyle toward healthy diets (including consumption of low-sugar and energy-dense foods and beverages) has been observed in recent years [2]. The NSS have become ubiquitous as common replacements for added sugar for reducing calorie content from free sugar, in general population and among specific group with obesity and diet-related noncommunicable diseases (NCD). They are being used widespread in global food supply, and are expected to grow up to 7.2% from 2022 to 2032, with an expected market value of US$ 46 Billion by the end of 2032[3].
Despite increasing evidence of the undesirable health impact of NSS, consumer perception of its safety (or hazard) remains low. According to a US adult consumer survey, almost one-third consumers perceived that non-nutritive sweeteners can be part of their overall healthful diet, while 73% of those consuming theses sweeteners consumed them because they wanted to reduce total calories ingested [4]. More than one-third US consumers (36%) were not concerned about the safety of artificial sweeteners [5]. As for urban growth, a wide use of artificial sweeteners was observed in urban population. Use of saccharin, acesulfame and sucralose were reported in all urban canal water population in Hanoi, Vietnam [6]. In India more than one-third of urban populations consumed artificial sweeteners each month, which some reported consuming these sweeteners in more than one food product [7]. The UK survey of a working-age sample found that approximately 30% of participants considered non-nutritive sweeteners as harmful, 40% were concerned about their effects on human body and almost 30% were concerned about increase in cancer risk[8]. These concerns could be influenced by consumer knowledge, and related government policy and regulation that can affect perceived benefits and risks of consumption of sweeteners in the population [8–10].
A significantly increased consumption of artificially sweetened beverages (ASB) has been observed in recent years [11]. ASB intake appears to increase with age and is more common among girls than boys, and among women than men, and that people trying to lose weight report a higher intake of ASB than those not trying to lose weight [12,13]. In addition, ASB consumers are more likely to be college educated [14]. It is reasonable to assume that the observed increased trend in frequency of consumption of ASB is partly due to greater accessibility and selection of ASB in addition to the promotion of ASB as a healthier alternative to SSB [15]. A study on consumption of sugar-sweetened beverages (SSB) and ASB from childhood to adulthood in relation to socioeconomic status – 15 years follow-up in Norway found a decrease in SSB consumption and an increase in ASB consumption from childhood to adulthood [16].
There are growing concerns about safety of NSS consumption in Thailand. Nonetheless, the published research on this topic includes only a limited number of small observational studies on ASB consumption in Thais [17,18]. Furthermore, none of those studies paid attention on the impacts of the rise of urbanisation on Thais’ diets and influence of education attainment on perception on ASB. No studies have used nationally representative data, explored key characteristics of Thais consuming ASB, or examined associations between ASB consumption and influential factors. Therefore, this study had the following two objectives: (1) To document the prevalence of ASB consumption in educated Thai adults in urban areas; and (2) To examine associations of ASB consumption with sociodemographic characteristics, lifestyle behaviors, and obesity in the study adults. The source of data is a large nationally-representative sample of the Thai population. Findings of this study should be useful for informing policy decisions and communication strategies to combat the harmful effects of NSS consumption in Thailand.
Methods
Study design and participants
This study used data from the 2021 population-based survey called the Health Behavior of Population Survey (HBPS). The HBPS was the largest population-based survey on NCD and their risk factors in Thailand conducted by the National Statistical Office of Thailand (NSO) [17]. The HBPS contains data from a nationally-representative sample, covering information on sociodemographic characteristics and food consumption of the Thai population age six years or over. Data collection was conducted during February – May, 2021.
The HBPS employed a two-stage sampling procedure to recruit study participants. Across all the major geographic regions, a systematic sampling of Thailand’s 77 provinces was conducted. From these selections, 20 enumeration areas (EA) within each province were systematically sampled. Within each EA, 16 households were chosen, and subsequently contacted. A list of family households was obtained. All household members who were eligible were invited to participate in the survey. However, it should be noted that the level of data accuracy from this survey can be affected by the sampling method. The NSO reported the percentage of coefficient of variation of main characteristics such as between consuming sugar-sweetened beverages, and age, sex and area of residence (rural, urban) ranging from 0.90–2.84 [17] which can be regarded as the excellent level of data accuracy.
The protocol for this study was initially reviewed by the Institutional Review Board of Institute for Population and Social Research of Mahidol University (COE. No. 2023/03–044). However, it was then exempt from further review for the current secondary analysis because it did not meet the criteria for human subjects’ research.
The NSO research team contacted the sampled households through a village leader in each EA. The interviews took approximately 30–45 minutes each. Respondents were given an opportunity to ask for clarification. A total of, 84,000 members of sampled households were successfully interviewed face-to-face by trained staff using a structured questionnaire.
There was a total of 62,891 eligible cases, as shown in S1 Table. In order to reach the prioritized target population, this study focused specifically on Thais age 20–64 years, living in an urban area, and had attained at least a Bachelor’s degree. There is evidence elsewhere that this population group had high SSB consumption [19], and are more likely to access/consume NSS compared with other population groups [20, 21]. That filter produced a net sample of 8,155 for this study.
Measures
Dependent variable.
Participants were asked about frequency of ASB consumption using the following question “In the past 30 days, how often did you consume an artificially sweetened beverage (ASB)?” Participants who reported consuming ASB at least once per week, which include consuming 1–2 days, 3–4 days, 5–6 days, or every day, were classified as “consume.” Those who did not consume ASB at all or consumed it only 1–3 days per month were classified as “not consumed”.
Independent variables.
Socio-demographic characteristics: Sex was included as a dichotomous variable, i.e., “male” or “female.” Age was categorised into two groups: “20-49 years”, and “50-64 years.” Marital status was classified into “single,” “married,” and “widowed/divorced/separated.”
Socio-economic status: For monthly cash income, participants who earned “less than or equal to 2,803 baht” and “more than 2,804 baht” were classified as being “poor” and “not poor,” respectively, according to Office of the National Economics and Social Development Council. Geographic area of residence was categorised into five groups: “Bangkok,” “Central,” “North,” “Northeast,” “South.”
Lifestyle behaviours: Smoking behavior was categorised into two groups: “no” (never smoke or used to smoke) and “yes” (smoke every day or smoke, but less than daily). Alcohol drinking was categorised into two groups: “no” (never drink, used to drink a year ago, drink 1–3 days per month, drink 8–11 days per year, drink 4–7 days per year, drink 1–3 days per year) and “yes” (drink every day, drink 5–6 days per week, drink 3–4 days per week, drink 1–2 days per week). Physical activity was categorised into two groups: “no” (not engaging in any vigorous exercise or playing sports) and “yes” (specifying the type of exercise or sport).
Health condition: Respondents were asked whether they currently have non-communicable disease(s). Response was divided into two groups: having at least one NCD -- classified as “yes”, and not having any NCD -- classified as “no.”
Nutritional status: Body Mass Index (BMI) was used as an indicator of overall nutrition status of the adult population. BMI was categorised into five groups: “Underweight (BMI < 18.5),” “Normal weight (BMI 18.5–22.9),” “Overweight (BMI = 23.0 - 24.9),” “Obesity Class 1 (BMI = 25.0–29.9),” and “Obesity Class 2 (BMI ≥ 30),” respectively, according to WHO standards [22].
Statistical analysis.
Descriptive statistics were used to analyse the socio-demographic and-economic characteristics, lifestyle behaviours, health condition, nutritional status, and ASB consumption. Binary logistic regression was applied to investigate associations between ASB consumption and sociodemographic characteristics, lifestyle behaviors, and obesity. The associations are presented as odds ratios (OR) with 95% confidence intervals (with p-values). The p-values were derived using the Chi-squared (χ2) test. The threshold for statistical significance of associations was set at p < 0.05. This study used the survey weighted data, thereby ensuring a more precise representation of the target population.
Results
Population description
Overall, sample characteristics are presented in S1 Table. Many survey participants were female (56.8%), obtained primary school education or less (43.1%), were married (62.9%), lived in a rural area (51.9%), were not poor (82.4%), did not smoke (82.2%), did not drink alcohol (85.7%), engaged in regular physical activity (42.9%), and had a normal weight (43.9%). The majority of the participants did not consume ASB (96.7%).
Characteristics of participants age 20–64 years resided in an urban area and attained at least a Bachelor’s degree, and their ASB consumption.
Table 1 shows key characteristics of study participants (age 20–64 years, living in an urban area and attaining at least a bachelor’s degree) who consumed ASB. They were female (57.0%), participants were age 20–49 years (73.5%), were married (51.8%), were lived in a Bangkok (33.1%), were not poor (92.1%), did not smoke (89.5%), did not drink alcohol (89.2%), engaged in regular physical activity (59.3%), did not have NCD disease (85.1%), and had a normal weight (47.1%). The participants did consume ASB (6.6%).
The participants who were female, age 50–64 years, were married, resided in the Central region, had healthy lifestyles (no smoking, no alcohol drinking, having physical activity), and had a NCD and were overweight/obese had a high percentage of ASB consumption compared with other variable(s) under the same category.
Significant relationships were observed between certain socio-demographic (e.g., sex, age, geographic areas of residence; p = 0.00) and socio-economic (e.g., poverty; p = 0.04) characteristics and ASB consumption among the study participants. The study also found relationships of ASB consumption with lifestyle behaviours (e.g., smoking, physical activity; p = 0.00), health condition (p = 0.00), and BMI (p = 0.00).
Associations between BMI, health condition and socio-demographic and lifestyle characteristics, and ASB consumption
Results of the binary logistic regression analysis are presented in Table 2. There were statistically significant associations between BMI, some lifestyle behaviors and some socio-demographic characteristics, and ASB consumption among the study participants.
Participants who were overweight/obese Class 1 had 1.5 times (OR = 1.49, 95% CI 1.18–1.88), and 1.4 times (OR = 1.36, 95% CI 1.08–1.72), respectively, more likely to consume ASB than those with normal weight.
The participants with no smoking (OR = 2.11, 95% CI 1.39–3.20), and having physical activity (OR = 1.91, 95% CI 1.57–2.33) were more likely to have higher ASB consumption than those who smoked and had no physical activity, respectively. Participants living with NCD more likely to consuming ASB than those living without an NCD (OR = 1.56, 95% CI 1.24–1.97).
Some socio-demographic characteristics (e.g., sex, age, geographic area of residence, education) were associated with ASB consumption. For example, males were 26.9% less likely to consume ASB (OR = 0.73, 95% CI 0.59–0.89) than females. Participants age 20–49 years had 29.4% less likely to consume ASB than those age 50–64 years (OR = 0.70, 95% CI 0.57–0.86). Participants who lived in Bangkok (OR = 2.32, 95% CI 1.56–3.43), the Central (OR = 2.58, 95% CI 1.74–3.38), and the Northeast region (OR = 1.82, 95% CI 1.17–2.83) were more likely to consume ASB than those in the South.
Discussion
This study describes the prevalence of ASB consumption in a national sample of the Thai population who primarily lived in an urban area and were age 20–64 years and obtained at least Bachelor’s degree. To our knowledge, this is the first study of key characteristics of Thais who consumed ASB, and examined the relationships between lifestyles, and nutritional and health characteristics and ASB consumption. This study found significant differences in ASB consumption by all sociodemographic and economic, lifestyle, and health factors. Strong associations were observed among consumers with high BMI, living with an NCD and healthy lifestyle behaviours.
In this study, participants who were overweight/obese Class 1 were more likely to have high ASB consumption. The control of weight comes in various forms, with the fundamental principle being that those seeking weight loss must manage their food intake and modify behavior, including regular, vigorous physical exercise. Therefore, artificial sweeteners are often introduced as substitutes for sugar, and their usage has increased [23]. There is evidence that sweeteners replacing sugar have advantages but do not contribute to weight loss [24]. Instead, they may lead to weight gain that may be due to increased consumption of food, driven by the accustomed sweetness [25,26]. Ironically then, in murine studies, NSS have a more significant impact on weight gain compared to the consumption of sugar [27]. Individuals who are at higher risk for weight gain or have high BMI may misunderstand the effect of ASB consumption on nutritional outcome and, thus, choose to consume ASB in an attempt to control their weight or reduce BMI. Some food companies showed careful consideration in replacing sugar with artificial sweeteners due to consumers’ concerns on health effects [28]. Therefore, given perceived concerns about the health safety of artificial sweeteners, it is important for the Thai government to develop effective communication strategies which convey accurate, clear, and concise information to consumers regarding the potentially-adverse health effects of ASB consumption. It is also important for the government to monitor and control ASB marketing strategies, especially their messaging that must be cautious about explicitly mentioning the health effects of the ASB products.
A statistically-significant association between NCD and ASB consumption was observed in this study. Participants who have one or more NCD were more likely to have high ASB consumption. This is not surprising, and could be explained by the fact that people with disease may compensate for the energy deficit which refers to a lack of energy resulting from various health-related circumstances, which compel the body to find ways to compensate for the energy shortfall. This may include increasing food intake or opting for non-nutritive sweeteners to maintain an appropriate energy balance by replacing caloric SSB with ASB in order to reduce or control their health risks [8,29]. This phenomenon may also be the result of the global recommendation to reduce free sugar intake as part of a healthier diet, advocated by many organisations such as WHO. That recommendation entails reducing non-essential energy intake, excess body weight, and diet-related NCD in general [30]. Nevertheless, there is increasing evidence of the association between higher artificial sweetener consumption and increased health risks [31–33]. A large prospective cohort study in France found association between total artificial sweetener intake and increased cardiovascular diseases risk (95% CI: 1.01–1.18, P = 0.03) [31]. Another large cohort study in the US found associations between high ASB consumption and higher risks of all stroke (hazard ratio = 1.23, 95% CI: 1.47–4.04), ischemic stroke (hazard ratio = 1.31, 95% CI: 1.06–1.63), for coronary heart disease (hazard ratio = 1.29, 95% CI: 1.11–1.51), and all-cause mortality (hazard ratio = 1.16, 95% CI: 1.07–1.26) [33]. Some study reviewed scientific evidence and found similar results showing associations between routine consumption of non-nutritive sweeteners and increased health risk such as ischemic stroke, cardiovascular disease, type 2 diabetes and hypertension [32]. It also found biological mechanisms by which the artificial sweeteners may cause negative health effects. Therefore, the high-risk or susceptible population group should use these products with utmost caution. What is more, Thailand’s dietary guidelines should address the effects of artificial sweeteners and ASB consumption. People at risk, care givers and health professionals should also be amply informed about the potential risks of using them.
This study found that not smoking and having regular, vigorous physical activity were significantly associated with higher ASB consumption. This finding is in line with some studies, reporting that high ASB consumers are more likely to be non-smoker or former smoker [34] and people who have high physical activity [35] such as athletes and fitness enthusiasts. Participants with healthy lifestyle are usually concerned about harmful behaviors to health which include foods they eat - whether they could be harmful to their health. The food concern can regard the composition of their diet including sugar content of foods and beverages. Together, food marketing from beverage companies were created in response to regulatory actions on SSB by using various strategies, including ASB formulation and sales and their promotion as healthier alternatives to SSB [15]. Accordingly, ASB becomes an attractive option for cutting back on added sugar for maintaining a healthy diet among people pursuing a healthy lifestyle as a goal [36]. Therefore, developing specific communication strategies to educate the healthy-lifestyle group is needed to help them to make more informed healthy choices.
This study also found an association of certain sociodemographic factors with ASB consumption. For example, participants age 20–49 years were less likely to consume ASB compared with those age 50–64 years. It is possible that, as people age, those in a more senior age group are more likely to experience adverse health conditions at the same time. Diet is one of key modifiable risk factors for ill health [37]. Therefore, a management of an adverse health condition (e.g., diabetes) through diet management, including limiting sugar intake, is needed, and its effectiveness has been demonstrated elsewhere [38]. This may result in replacing diets of the older-age cohort with foods containing artificial sweeteners and other sugar-substituted foods with fewer or no calories, e.g., ASB. Moreover, people who live in Bangkok (capital city), the Central and Northeast regions were more likely to consume ASB [39] as compared to those in South region. This finding might be explained by food culture in each region. Compared to other regions, Southern Thai food is characterized by its spice and sharpness, with spicy and salty flavours [40]. Foods in other regions especially the Central and Bangkok have more neutral flavor - balancing sour, salty, spicy, bitter and sweet flavours. This difference may influence ASB consumption behaviours among people of different regions. Previous studies reported that people in these regions had greater consumption of SSB, particularly non-alcoholic carbonated and energy drinks, which contain a higher level of sugar than other types of SSB [41], compared with those residing in other regions [19]. With the growing concerns about the rise of obesity, diabetes, and other health problems, consumers in the two regions, therefore, may be more aware of this and, thus, may increasingly seek low- or no-calorie alternatives (such as ASB) to replace SSB. These findings point to the importance of improvement in food literacy of individuals to increase their ability to make their own healthy and safe food choices as well as for their family and community.
This study has some limitations. First, as the data collection was cross-sectional, causality cannot be inferred. However, this study was able to provide the most up-to-date, national overview of prevalence of ASB consumption in this group of Thai population, highlighting the key characteristics of ASB consumers and the associations between the socio-demographic, lifestyle, health factors and ASB consumption. Second, the authors acknowledge that the variable set used in this study did not include environmental and macro-level factors, and those can impact eating behaviours of individuals as well [42]. Future research is needed which analyses the interplay of multiple factors and their influence on ASB consumption. Moreover, the study population was mostly those in the working-age group, who live in an urban area, and had attained at least a Bachelor’s degree. The results of this study may not be applicable to the general population. However, the findings should be useful in the development of appropriate health policies and interventions in a specific population group – particularly the group with high ASB consumption, as those individuals should be government’s priority. This effort should be undertaken through policies and actions in food literacy and marketing control to improve the consumer profile, and create healthiness of the food environment which can lead to increasing access to healthy beverage products.
Conclusions
The findings of this study suggest that being male, being age 20–49 years, living in Bangkok, the Central or the Northeast region, being a non-smoker, having adequate physical activity, having high BMI and having NCD were associated with high ASB consumption. This highlights the need for the Thai government to develop effective communication strategies that convey accurate, clear, and concise information to consumers regarding the health effects of ASB consumption in order for them to make their own healthy and safe food choices.
Supporting information
S1 Table. Socio-demographic and socio-economic characteristics of the HPBS sample.
https://doi.org/10.1371/journal.pone.0322553.s001
(DOCX)
Acknowledgments
The authors would like to thank all respondents for taking time to complete the HBPS, and the NSO for sampling and collecting such useful information that can be used for many purposes.
References
- 1. World Health Organization. Use of non-sugar sweeteners: WHO guideline. 2023. Available from: https://www.who.int/publications/i/item/9789240073616.
- 2. Aschemann-Witzel J, Grunert KG. Influence of ‘soft’ versus ‘scientific’ health information framing and contradictory information on consumers’ health inferences and attitudes towards a food supplement. Food Quality and Preference. 2015;42:90–9.
- 3. Future market Insights. Low-calorie sweeteners market outlook (2022-2032). 2022 Available from: https://www.futuremarketinsights.com/reports/low-calorie-sweeteners-market.
- 4. Food Insight. International food information council foundation. 2012 Food & health survey: consumer attitudes toward food safety, nutrition and health. 2012. Available from: https://foodinsight.org/2012-food-and-health-survey/.
- 5. Pereira M. Acting sweet: drivers, trends and forecasts in the sugar-free food and beverage market are explored. CBS Interactive. 2012.
- 6. Li D, Zheng Q, Thomas KV, Dang AK, Binh VN, Anh NTK, et al. Use of artificial sweeteners and caffeine in a population of Hanoi: an assessment by wastewater-based epidemiology. Sci Total Environ. 2023;868:161515. pmid:36634775
- 7. Local Circles. 38% urban Indians surveyed confirm consuming foods with artificial sweeteners each month; 91% want food brands to display usage of artificial sweeteners on front of the pack. Available from: https://www.localcircles.com/a/press/page/artificial-sweeteners-survey.
- 8. Farhat G, Dewison F, Stevenson L. Knowledge and perceptions of non-nutritive sweeteners within the UK adult population. Nutrients. 2021;13(2):444.
- 9. Bearth A, Cousin M-E, Siegrist M. The consumer’s perception of artificial food additives: Influences on acceptance, risk and benefit perceptions. Food Qual. 2014;38:14-23.
- 10. Varela P, Fiszman S. Exploring consumers’ knowledge and perceptions of hydrocolloids used as food additives and ingredients. Food Hydrocoll. 2013;30(1):477–84.
- 11. Sylvetsky AC, Rother KI. Trends in the consumption of low-calorie sweeteners. Physiol Behav. 2016;164:446–50. pmid:27039282
- 12. Paulsen MM, Myhre JB, Andersen LF. Beverage consumption patterns among norwegian adults. Nutrients. 2016;8(9):561. pmid:27649236
- 13. Pereira MA. Diet beverages and the risk of obesity, diabetes, and cardiovascular disease: a review of the evidence. Nutr Rev. 2013;71(7):433–40. pmid:23815142
- 14. Drewnowski A, Rehm C. Socio-demographic correlates and trends in low-calorie sweetener use among adults in the United States from 1999 to 2008. Eur J Clin Nutr. 2015; 69(9):1035–41.
- 15. Borges MC, Louzada ML, de Sá TH, Laverty AA, Parra DC, Garzillo JMF, et al. Artificially sweetened beverages and the response to the global obesity crisis. PLoS Med. 2017;14(1):e1002195. pmid:28045913
- 16. Bolt-Evensen K, Vik FN, Stea TH, Klepp K-I, Bere E. Consumption of sugar-sweetened beverages and artificially sweetened beverages from childhood to adulthood in relation to socioeconomic status–15 years follow-up in Norway. Int J Behav Nutr Phys Act. 2018;15: 1-9.
- 17.
National Statistical Office. Health behavior of population survey. Ministry of Digital Economy and Society Thailand;2021.
- 18. Papier K, D’Este C, Bain C, Banwell C, Seubsman S-a, Sleigh A, et al. Consumption of sugar-sweetened beverages and type 2 diabetes incidence in Thai adults: results from an 8-year prospective study. Nutr Diabetes. 2017;7(6):e283. pmid:28628126
- 19. Phulkerd S, Thongcharoenchupong N, Chamratrithirong A, Pattaravanich U, Sacks G, Prasertsom P. Influence of sociodemographic and lifestyle factors on taxed sugar-sweetened beverage consumption in Thailand. Food Policy. 2022;109:102256.
- 20. Moreira TKB, Santos HCD, Mendes FD, Molina MDCB, Mill JG, Faria CPd. Examining the usage patterns of non-nutritive sweeteners among non-diabetic individuals: insights from the longitudinal study of adult health (ELSA-Brasil). Nutrients. 2023;15(22):4785. pmid:38004179
- 21. Debras C, Deschasaux-Tanguy M, Chazelas E, Sellem L, Druesne-Pecollo N, Esseddik Y, et al. Artificial sweeteners and risk of Type 2 diabetes in the prospective nutrinet-santé cohort. Diabetes Care. 2023;46(9):1681–90. pmid:37490630
- 22. World Health Organization, Regional Office for the Western Pacific. The Asia-Pacific perspective: redefining obesity and its treatment. Health Communications Australia. 2000.
- 23. Sun T, Yang J, Lei F, Huang X, Liu W, Zhang X, et al. Artificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank. Cardiovasc Diabetol. 2024;23(1):233. pmid:38965574
- 24. Gibson S, Drewnowski A, Hill J, Rabben AB, Tuorila H, Widström E. Consensus statement on benefits of low-calorie sweeteners. Nutr Bull. 2014; 39(4), 386-389.
- 25. Cabral TM, Pereira MGB, Falchione AEZ, de Sá DAR , Correa L, da Maia Fernandes D, et al. Artificial sweeteners as a cause of obesity: weight gain mechanisms and current evidence. Health. 2018;10(05):700.
- 26. Azad MB, Abou-Setta AM, Chauhan BF, Rabbani R, Lys J, Copstein L, et al. Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies. CMAJ. 2017;189(28):E929–39. pmid:28716847
- 27. de Matos Feijó F, Ballard CR, Foletto KC, Batista BAM, Neves AM, Ribeiro MFM, et al. Saccharin and aspartame, compared with sucrose, induce greater weight gain in adult Wistar rats, at similar total caloric intake levels. Appetite. 2013;60:203–7. pmid:23088901
- 28. Forde H, Penney TL, White M, Levy L, Greaves F, Adams J. Understanding marketing responses to a tax on sugary drinks: a qualitative interview study in the United Kingdom, 2019. Int J Health Policy Manag. 2022;11(11):2618–29. pmid:35219285
- 29. Alharthi SA, Alaisayi KHA, Alalawi LYS, Alamri ROS, Abu-Elfotuh K, Alenazi TS, et al. The consumption pattern and perception of using artificial sweeteners among the public in Tabuk region, Saudi Arabia. Front Public Health. 2023;11:1166868. pmid:37427264
- 30. World Health Organization. WHO calls on countries to reduce sugars intake among adults and children. 2015. Available from: https://www.who.int/news/item/04-03-2015-who-calls-on-countries-to-reduce-sugars-intake-among-adults-and-children.
- 31. Debras C, Chazelas E, Sellem L, Porcher R, Druesne-Pecollo N, Esseddik Y, et al. Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort. BMJ, 2022; 378.
- 32. Swithers SE. Not-so-healthy sugar substitutes?. Curr Opin Behav Sci. 2016;9:106–10. pmid:27135048
- 33. Mossavar-Rahmani Y, Kamensky V, Manson JE, Silver B, Rapp SR, Haring B, et al. Artificially sweetened beverages and stroke, coronary heart disease, and all-cause mortality in the Women’s Health Initiative. Stroke. 2019;50(3):555–62. pmid:30802187
- 34. Zhao L, Zhang X, Coday M, Garcia DO, Li X, Mossavar-Rahmani Y, et al. Sugar-sweetened and artificially sweetened beverages and risk of liver cancer and chronic liver disease mortality. JAMA. 2023;330(6):537–46. pmid:37552302
- 35. Machek SB, Willoughby DS. Non-nutritive sweeteners: implications for consumption in athletic populations. Strength Cond J. 2019;41(4):112-26.
- 36. Edwards CH, Rossi M, Corpe CP, Butterworth PJ, Ellis PR. The role of sugars and sweeteners in food, diet and health: alternatives for the future. Trends in Food Science & Technology. 2016;56:158–66.
- 37. Keller HH. Promoting food intake in older adults living in the community: a review. Appl Physiol Nutr Metab. 2007;32(6):991-1000.
- 38. Pastors JG, Warshaw H, Daly A, Franz M, Kulkarni K. The evidence for the effectiveness of medical nutrition therapy in diabetes management. Diabetes Care. 2002;25(3):608–13. pmid:11874956
- 39. Popkin BM, Nielsen SJ. The sweetening of the world’s diet. Obes Res. 2003;11(11):1325–32. pmid:14627752
- 40.
Narathiwat Provincial Cultural Office. Thai food culture: southern region. 2013.
- 41. Phulkerd S, Thongcharoenchupong N, Chamratrithirong A, Soottipong Gray R, Prasertsom P. Changes in population-level consumption of taxed and non-taxed sugar-sweetened beverages (SSB) after implementation of SSB excise tax in Thailand: a prospective cohort study. Nutrients. 2020;12(11):3294. pmid:33121147
- 42. Story M, Kaphingst KM, Robinson-O’Brien R, Glanz K. Creating healthy food and eating environments: policy and environmental approaches. Annu Rev Public Health. 2008;29:253–72. pmid:18031223