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Open Access

Expression of Concern

Expression of Concern: The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons

  • The PLOS ONE Editors

After this article [1] was published, concerns were raised about results presented in Figs 4 and 8. Specifically:

  • The Tau panels in Fig 4A–4C appear similar to each other.
  • There appears to be a vertical discontinuity between lanes 4 and 5 in the AT8 blot in Fig 8A.
  • There appear to be vertical discontinuities between lanes 1 and 2 in the Tau and AT180 blots in Fig 8B.

The authors did not respond to queries about the experiments in Figs 4 and 8.

In light of the unresolved concerns in Figs 4 and 8, the PLOS ONE Editors issue this Expression of Concern.

Reference

  1. 1. Rahman A, Ting K, Cullen KM, Braidy N, Brew BJ, Guillemin GJ (2009) The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons. PLoS ONE 4(7): e6344. https://doi.org/10.1371/journal.pone.0006344 pmid:19623258

Citation: The PLOS ONE Editors (2024) Expression of Concern: The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons. PLoS ONE 19(11): e0314139. https://doi.org/10.1371/journal.pone.0314139

Published: November 14, 2024

Copyright: © 2024 The PLOS ONE Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.