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Open Access

Retraction

Retraction: The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis

  • The PLOS ONE Editors

After this article [1] was published, two studies included in the meta-analysis were retracted ([2–5]; cited as references 24 and 26 in [1]).

The main conclusion of [1] is that sildenafil usage during pregnancy is associated with increased fetal weight at birth. The authors of [1] redid the meta-analysis with [2] and [3] excluded, and found that the reported conclusion was not supported. This was confirmed by a member of the PLOS ONE Editorial Board.

In light of the above concern, the PLOS ONE Editors retract this article.

RDdSF, RN, and WMB agreed with the retraction. RS and SP either did not respond directly or could not be reached.

References

  1. 1. Ferreira RDdS, Negrini R, Bernardo WM, Simões R, Piato S (2019) The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis. PLoS ONE 14(7): e0219732. https://doi.org/10.1371/journal.pone.0219732 pmid:31339910
  2. 2. Maher MA, Sayyed TM, Elkhouly N. Sildenafil citrate therapy for oligohydramnios: A Randomized Controlled Trial. Obstet Gynecol. 2017;129(4): 615–20. pmid:28277352
  3. 3. El-Sayed M. A., Saleh S. A. A., Maher M. A., & Khidre A. M. (2017). RETRACTED ARTICLE: Utero-placental perfusion Doppler indices in growth restricted fetuses: effect of sildenafil citrate. The Journal of Maternal-Fetal & Neonatal Medicine, 31(8), 1045–1050.
  4. 4. Notice of Retraction: “Sildenafil Citrate Therapy for Oligohydramnios: A Randomized Controlled Trial” (Maher MA, Sayyed TM, and Elkhouly N). Obstetrics & Gynecology 2020;135(4): 980. pmid:32150003
  5. 5. Statement of Retraction: Utero-placental perfusion Doppler indices in growth restricted fetuses: effect of sildenafil citrate. (2024). The Journal of Maternal-Fetal & Neonatal Medicine, 37(1): 2360745. https://doi.org/10.1080/14767058.2024.2360745 pmid:38871486

Citation: The PLOS ONE Editors (2024) Retraction: The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis. PLoS ONE 19(9): e0310291. https://doi.org/10.1371/journal.pone.0310291

Published: September 6, 2024

Copyright: © 2024 The PLOS ONE Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.