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Correction

Correction: Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model

  • The PLOS ONE Staff

Fig 1B and 1C, “The evaluation of the CAFs marker on each treatment day.” does not appear. Please view Fig 1 here.

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Fig 1. The evaluation of the CAFs marker on each treatment day.

(A) qRT-PCR analysis. The mRNA expression was evaluated weekly and at the endpoint. The expression of all the markers increased significantly over time *p < 0.05). (B) Immunohistochemical staining. All images were recorded at 200×magnification. (C) Immunohistochemical Evaluation. The IRS scores for all markers significantly increased over time *p < 0.05).

https://doi.org/10.1371/journal.pone.0307334.g001

Fig 3B and 3C, “The effect of transcutaneous CO2 treatment.” does not appear. Please view Fig 3 here.

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Fig 3. The effect of transcutaneous CO2 treatment.

(A) qRT-PCR analysis. The expression of each marker was evaluated on Day 25. Compared with the control group, the expression of α-SMA, FAP, PDPN, and TGF-β was significantly suppressed in the CO2-treated group. *p < 0.05. (B) Immunohistochemical staining (magnification: 200×). (C) Immunohistochemical evaluation. The IRS score of all markers was significantly suppressed in the CO2-treated group. *p < 0.05.

https://doi.org/10.1371/journal.pone.0307334.g002

The publisher apologizes for the errors.

Reference

  1. 1. Tadokoro Y, Takeda D, Murakami A, Yatagai N, Saito I, Arimoto S, et al. (2023) Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model. PLoS ONE 18(8): e0290357. https://doi.org/10.1371/journal.pone.0290357 pmid:37594996

Citation: The PLOS ONE Staff (2024) Correction: Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model. PLoS ONE 19(7): e0307334. https://doi.org/10.1371/journal.pone.0307334

Published: July 11, 2024

Copyright: © 2024 The PLOS ONE Staff. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.