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Open Access

Correction

Correction: EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference

  • Chen Chen,
  • Heng Mei,
  • Wei Shi,
  • Jun Deng,
  • Bo Zhang,
  • Tao Guo,
  • Huafang Wang,
  • Yu Hu

After this article [1] was published it was noted that Fig 1D and 1E showed overlapping fields of the same data at slightly different magnifications. In the corrected Fig 1 provided here, panel D has been replaced with the correct data from the original experiment. The original underlying data files for panels D and E are in S1 and S2 Files, respectively.

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Fig 1. The different nanoparticles that were negatively stained with a 1% phosphotungstic acid solution.

(A) siRNA-loaded NPs stained with EGF primary antibody and with 10 nM of colloidal gold-labeled rabbit anti-goat IgG. (B) siRNA-loaded ENPs stained with 10 nM of colloidal gold-labeled rabbit anti-goat IgG. (C) siRNA-loaded ENPs stained with EGF primary antibody and stained with 10 nM of colloidal gold-labeled rabbit anti-goat IgG. The arrows point to the fusion protein EGF1, which conjugated to the surfaces of the nanoparticles. (D) siRNA-loaded NPs. (E) siRNA-loaded ENPs. The bars shown in (D) and (E) are 200 nm.

https://doi.org/10.1371/journal.pone.0303121.g001

Supporting information

S1 File. Original data underlying Fig 1D.

https://doi.org/10.1371/journal.pone.0303121.s001

(JPG)

S2 File. Original data underlying Fig 1E.

https://doi.org/10.1371/journal.pone.0303121.s002

(JPG)

Reference

  1. 1. Chen C, Mei H, Shi W, Deng J, Zhang B, Guo T, et al. (2013) EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference. PLoS ONE 8(4): e60860. https://doi.org/10.1371/journal.pone.0060860 pmid:23593330

Citation: Chen C, Mei H, Shi W, Deng J, Zhang B, Guo T, et al. (2024) Correction: EGFP-EGF1-Conjugated PLGA Nanoparticles for Targeted Delivery of siRNA into Injured Brain Microvascular Endothelial Cells for Efficient RNA Interference. PLoS ONE 19(5): e0303121. https://doi.org/10.1371/journal.pone.0303121

Published: May 1, 2024

Copyright: © 2024 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.