After this article [1] was published, concerns were raised about Figs 2A, 3A, and 5C.

Specifically:

• The WT and RIPK1-D138N panels in Fig 2A of [1] appear similar to the tMCAO and Sham panels, respectively, in Fig 2A of a previous article with no shared authors [2].
• The Sham, WT, Ripk1^D138N and Ripk3-/- panels in Fig 3A of [1] appear similar to the Sham, 3d, 12h and 7d panels, respectively, in Fig 1C of [2].
• The Sham, Ctrl, and A20-EKD panels in Fig 5C of [1] appear similar to the Sham, tMCAO/vehicle, and tMCAO/nec-1 panels respectively in Fig 2H of [2].
• In the S1 Raw images file, the images provided for the p-RPK1 wild type and β-actin panels in Fig 1 appear similar, when flipped horizontally, and do not match the p-RPK1 wild type data shown in the figure.
• The data in the S1 Raw images file for Fig 5 and for the Fig 4 β-actin panel do not match the results shown in the figures.

The corresponding author requested the retraction of this article [1] and stated that the underlying data was not labeled sufficiently to allow for accurate identification of the results.

In light of the above concerns, the PLOS ONE Editors retract this article.

MG, YL, and YW agreed with retraction. CY and XW either did not respond directly or could not be reached.