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Expression of Concern

Expression of Concern: Hyaluronan Hybrid Cooperative Complexes as a Novel Frontier for Cellular Bioprocesses Re-Activation

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After this article [1] was published, concerns were raised about Fig 9. Specifically, the CTR panels appear to partially overlap with the L-HA panels despite representing different experimental conditions.

The corresponding author stated this was caused by an error in the preparation of the figures and provided a corrected panel and the underlying data, included with this notice. The PLOS ONE Editors are satisfied that this concern has been resolved in full and that the conclusions of the article are not affected.

In reviewing this matter, it was noted that the underlying primary data were not provided with the published article, contrary to the Data Availability statement. The authors stated that the underlying quantitative data for Figs 5 and 10 were no longer available, but provided underlying data for all remaining figures. As such this article currently does not comply with the PLOS ONE Data Availability policy that was in place at the time of publication. The available data are provided with this notice.

In light of the above concern pertaining to data availability, the PLOS ONE Editors issue this Expression of Concern.

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Fig 9. Keratinocytes-fibroblasts immunofluorescence pictures relative to ELS expression in presence of H-HA, L-HA and H/L-HA complexes 0.16% (w/w) at 7 days.

Blue: Nuclei (Hoechst), Green: ELS, red: Cytoskeleton (Phalloidin).

https://doi.org/10.1371/journal.pone.0302213.g001

Supporting information

S1 File. Underlying data for Figs 1–4 and 6.

https://doi.org/10.1371/journal.pone.0302213.s001

(ZIP)

S2 File. Underlying data for Figs 7–9 and 11.

https://doi.org/10.1371/journal.pone.0302213.s002

(ZIP)

Reference

  1. 1. Stellavato A, Corsuto L, D’Agostino A, La Gatta A, Diana P, Bernini P, et al. (2016) Hyaluronan Hybrid Cooperative Complexes as a Novel Frontier for Cellular Bioprocesses Re-Activation. PLoS ONE 11(10): e0163510. pmid:27723763

Citation: The PLOS ONE Editors (2024) Expression of Concern: Hyaluronan Hybrid Cooperative Complexes as a Novel Frontier for Cellular Bioprocesses Re-Activation. PLoS ONE 19(4): e0302213. https://doi.org/10.1371/journal.pone.0302213

Published: April 10, 2024

Copyright: © 2024 The PLOS ONE Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.