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Open Access

Retraction

Retraction: SATB1 Overexpression Regulates the Development and Progression in Bladder Cancer through EMT

  • The PLOS ONE Editors

This article [1] was identified as one of a group of articles connected by concerns about image reuse [2–13].

The image concerns in this article [1] affect Figs 3 and 6. Specifically,

  • In Fig 3, the following western blot results appear similar:
    1. ○ Fig 3B ZEB2 panel lanes 2–3 and Fig 3B GAPDH panel lanes 1–2 when stretched across the horizontal and vertical axes.
    2. ○ Fig 3D Snail and Fig 3D Vimentin panels.
  • The following panels appear to partially overlap:
    1. ○ Fig 6A BIU-87 Migration of [1] and Fig 2A MDA-MB-231 miR-181b+CCL18 of [2].
    2. ○ Fig 6A Control vector Migration of [1] and Fig 2B MCF-7 miR-181b+CCL18 of [2].
    3. ○ Fig 6A pcDNA3.1-SATB1 Migration of [1] and Fig 2B MCF-7 CCL18 of [2].
    4. ○ Fig 6A BIU-87 Invasion of [1] and Fig 2A MCF-7 miR-181b+CCL18 of [2].
    5. ○ Fig 6A Control vector Invasion of [1] and Fig 2A MDA-MB-231 CCL18 of [2].
    6. ○ Fig 6A pcDNA3.1-SATB1 Invasion of [1], Fig 2A MCF-7 CCL18 of [2], Fig 2B MDA-MB-231 CCL18 of [2], and Fig 2B MDA-MB-231 miR-181b+CCL18 of [2].
    7. ○ Fig 6B T24 Invasion of [1], Fig 4A Migration Control Vector of [3–4], and Fig 3D Eca-109/pCMV-SOX2-Ctr siRNA of [5].

The authors did not comment on the above concerns.

The PLOS ONE Editors retract this article [1] due to the above image concerns that call into question the reliability of the reported results.

FW agreed with the retraction. CC, ZW, XX, HZ, SX, XC, JW, SL, YZ, WX, ZZ, CJ, and ZZ either did not respond directly or could not be reached.

References

  1. 1. Wan F, Cheng C, Wang Z, Xiao X, Zeng H, Xing S, et al. (2015) SATB1 Overexpression Regulates the Development and Progression in Bladder Cancer through EMT. PLoS ONE 10(2): e0117518. https://doi.org/10.1371/journal.pone.0117518 pmid:25706386
  2. 2. Wang L, Wang YX, Chen LP, Ji ML (2016) Upregulation of microRNA-181b inhibits CCL18-induced breast cancer cell metastasis and invasion via the NF-κB signaling pathway. Oncology Letters 12(6): 4411–4418. https://doi.org/10.3892/ol.2016.5230
  3. 3. Cheng C, Wan F, Liu L, Zeng F, Xing S, Wu X, et al. (2014) Overexpression of SATB1 Is Associated with Biologic Behavior in Human Renal Cell Carcinoma. PLoS ONE 9(5): e97406. https://doi.org/10.1371/journal.pone.0097406 pmid:24835085
  4. 4. The PLOS ONE Editors (2024) Retraction: Overexpression of SATB1 Is Associated with Biologic Behavior in Human Renal Cell Carcinoma. PLoS ONE 19(4): e0301571. https://doi.org/10.1371/journal.pone.0301571
  5. 5. Gao H, Teng C, Huang W, Peng J, Wang C (2015) SOX2 Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3/HIF-α Signaling. International Journal of Molecular Sciences 16(9): 21643–21657. https://doi.org/10.3390/ijms160921643
  6. 6. Jiang LT, Wan CH, Guo QH, Yang SJ, Wu JD, Cai J (2018) Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes Renal Cell Carcinoma Progression via Sponging miRNA-429. Medical Science Monitor 24: 1794–1801. https://doi.org/10.12659/MSM.909450 pmid:29588438
  7. 7. Cui SQ, Wang H (2015) MicroRNA-144 inhibits the proliferation, apoptosis, invasion, and migration of osteosarcoma cell line F5M2. Tumor Biology 36: 6949–6958. https://doi.org/10.1007/s13277-015-3396-0 pmid:25854173
  8. 8. Shi J, Zhang D, Zhong Z, Zhang W (2019) lncRNA ROR promotes the progression of renal cell carcinoma through the miR-206/VEGF axis. Molecular Medicine Reports 20(4): 3782–3792. https://doi.org/10.3892/mmr.2019.10636
  9. 9. Yue D, Qin X (2018) miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells. Cancer Gene Therapy 26: 1–10. https://doi.org/10.1038/s41417-018-0031-4 pmid:29925897
  10. 10. Pei X, Li M, Zhan J, Yu Y, Wei X, Guan L, et al. (2015) Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression. PLoS ONE 10(4): e0124338. https://doi.org/10.1371/journal.pone.0124338
  11. 11. The PLOS ONE Editors (2024) Retraction: Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression. PLoS ONE 19(4): e0301575. https://doi.org/10.1371/journal.pone.0301575
  12. 12. Zhou L, Zhang N, Song W, You N, Li Q, Sun W, et al. (2013) The Significance of Notch1 Compared with Notch3 in High Metastasis and Poor Overall Survival in Hepatocellular Carcinoma. PLoS ONE 8(2): e57382. https://doi.org/10.1371/journal.pone.0057382 pmid:23468978
  13. 13. The PLOS ONE Editors (2024) Retraction: The Significance of Notch1 Compared with Notch3 in High Metastasis and Poor Overall Survival in Hepatocellular Carcinoma. PLoS ONE 19(4): e0301556. https://doi.org/10.1371/journal.pone.0301556

Citation: The PLOS ONE Editors (2024) Retraction: SATB1 Overexpression Regulates the Development and Progression in Bladder Cancer through EMT. PLoS ONE 19(4): e0301572. https://doi.org/10.1371/journal.pone.0301572

Published: April 2, 2024

Copyright: © 2024 The PLOS ONE Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.