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Expression of Concern: Comparison of clinical and radiographic signs of hip osteoarthritis in contralateral hip joints of fifty working dogs

  • The PLOS ONE Editors

After publication of this article [1], concerns were raised about possible overlap or re-use of datasets and potential data discrepancies across a group of closely related publications [16]. The studies reported previously in [24] and [6] were not cited and discussed in [1]. In following up on these issues, the following was noted with regard to the datasets reported in these studies:

  • The three articles [13] each report a sample of 30 male and 20 female working dogs with the same overall aggregate weight and age data. The weight and age data for the 50-animal sample in Table 1 of article [1] are the same as in Table 1 of article [2] but there are minor differences in weight and age data reported by breed and sex in Table 1 of article [1] compared to Table 1 of article [3].
  • Table 1 in article [1] and Table 1 in article [3] also report individual stance analysis, thigh girth and range of motion (extension and flexion) measurements by breed and sex; in article [1] the left and right pelvic limb data are presented separately, in article [3] the left and right pelvic limb data are presented together.
  • Table 2 of article [1] and Table 2 of article [3] report broadly similar findings in radiographic evaluations; in article [1] the radiographic findings are presented by left and right pelvic limbs, whereas in article [3] the data are not separated by limb.

The corresponding author stated that these articles are part of a larger project which was run with a specific population of police working dogs, a relatively homogenous sample in terms of breeds, size, and conformation, and that article [3] is a descriptive study, where clinical and diagnostic imaging findings of this group of animals with bilateral hip osteoarthritis have different characteristics to companion dogs, while article [1] follows an experimental and more academic approach which looked at each joint individually to determine if there is a level of symmetry in animals with bilateral hip OA.

The corresponding author has also indicated that because of legal restrictions, the authors are unable to provide the PLOS ONE Editors with the underlying individual level data for this study. The published route for requesting access to the underlying data does not seem to be functional at the time of publication of this notice.

Where differences are observed between the datasets, it has not been possible to confirm the accuracy of the data reported in this PLOS ONE article [1].

In light of the unresolved questions about the datasets, the PLOS ONE Editors issue this Expression of Concern.

References

  1. 1. Alves JC, Santos A, Jorge P, Lavrador C, Carreira LM (2021) Comparison of clinical and radiographic signs of hip osteoarthritis in contralateral hip joints of fifty working dogs. PLoS ONE 16(3): e0248767. pmid:33735210
  2. 2. Alves J.C.A., dos Santos A.M.M.P., Jorge P.I.F. et al. Thermographic imaging of police working dogs with bilateral naturally occurring hip osteoarthritis. Acta Vet Scand 62, 60 (2020). pmid:33172488
  3. 3. Alves J.C., Santos A., Jorge P. et al. Clinical and diagnostic imaging findings in police working dogs referred for hip osteoarthritis. BMC Vet Res 16, 425 (2020). pmid:33160336
  4. 4. Alves J.C., Santos A., Jorge P. et al. Intraarticular triamcinolone hexacetonide, stanozolol, Hylan G-F 20 and platelet concentrate in a naturally occurring canine osteoarthritis model. Sci Rep 11, 3118 (2021). pmid:33542412
  5. 5. Alves J.C., Santos A., Jorge P. et al. Evaluation of digital thermography imaging to assess and monitor treatment of police working dogs with naturally occurring hip osteoarthritis. BMC Vet Res 17, 180 (2021). pmid:33933090
  6. 6. Alves JC, Santos A, Jorge P, Lavrador C and Carreira LM (2021) Intra-articular Injections With Either Triamcinolone Hexacetonide, Stanozolol, Hylan G-F 20, or a Platelet Concentrate Improve Clinical Signs in Police Working Dogs With Bilateral Hip Osteoarthritis. Front. Vet. Sci. 7:609889. pmid:33537353