Figures
In the Methods and Materials section, there is an error in the second sentence of the third paragraph. The correct sentence is: Rats in Lop and BBG9-1 groups were subcutaneously injected with 5.0 mg/kg of loperamide hydrochloride (Sigma, St. Louis, MO, USA), twice a daily, for 4 consecutive days to induce constipation.
There is an error in the caption for Fig 1. There are also errors in Fig 4. The authors have provided corrected versions of both below.
(A) Number of feces, (B) Fecal water content, and (C) Fecal hardness were measured every experimental day. (D) Correlation between fecal water content and hardness was assessed at day 4. Values are means ± standard error (SE) of 16 animals. * and **, p < 0.05 and 0.01 vs. Normal; # and ##, p < 0.05 and 0.01 vs. Lop.
(A) PCoA showed the clustered communities of fecal microbiota based on the Bray-Curtis dissimilarity between samples. (B) The calculated distance of Normal, Lop, and BBG9-1 groups in Bray-Curtis distance analysis. (C) The relative abundance of each bacterial genus was analyzed using 5000 next-generation sequencing reads of bacterial 16S rDNA. Values are means ± SE of 15 or 16 animals. * and **, p < 0.05 and 0.01 vs. Normal; #, p < 0.05 vs. Lop.
Reference
- 1. Makizaki Y, Uemoto T, Yokota H, Yamamoto M, Tanaka Y, Ohno H (2021) Improvement of loperamide-induced slow transit constipation by Bifidobacterium bifidum G9-1 is mediated by the correction of butyrate production and neurotransmitter profile due to improvement in dysbiosis. PLoS ONE 16(3): e0248584. https://doi.org/10.1371/journal.pone.0248584 pmid:33750988
Citation: Makizaki Y, Uemoto T, Yokota H, Yamamoto M, Tanaka Y, Ohno H (2022) Correction: Improvement of loperamide-induced slow transit constipation by Bifidobacterium bifidum G9-1 is mediated by the correction of butyrate production and neurotransmitter profile due to improvement in dysbiosis. PLoS ONE 17(4): e0267927. https://doi.org/10.1371/journal.pone.0267927
Published: April 27, 2022
Copyright: © 2022 Makizaki et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.