Figures
The twelfth sentence beneath the “Ussing chamber studies” sub-heading in the Methods section is incorrect. The correct sentence is: For exogenous prostaglandin experiments, 10μM 16,16-dimethylprostaglandin E2 was added to the basolateral chamber after the 15-minute reading for the remainder of recovery.
There is an error in the Fig 5 caption. Please see the figure and corrected caption here.
(A) Representative histology of control, 30-minutes ischemic and 120-minutes ex vivo recovery neonatal jejunum with the addition of 10uM 16,16-dimethylprostaglandin E2 to the basolateral chamber. Note the persistent epithelial defect in the recovered tissue (scale bars 100 μm). (B) Histomorphometry quantified 74±2.5% and 68±13.3% epithelialization in injured and prostaglandin recovered tissues, respectively, as compared to 98±2.0% epithelialization of controls (n = 3, n.s. = not significant, **P<0.01, unpaired t-test). (C) Representative histology of control, 30-minutes ischemic, and 30-minutes ischemic and 120-minutes full-thickness ex vivo recovery neonatal jejunum (scale bars 100 μm). (D) Histomorphometry quantified 30±6.3% and 27±12.6% epithelialization in injured and full thickness ex vivo recovered tissues, respectively, as compared to 100±0.0% epithelialization of controls (n = 4, n.s. = not significant, ****P<0.0001, unpaired t-test). (E) Representative histology of control, 30-minutes ischemic, and 30-minutes ischemic and 120-minutes in vivo recovery neonatal jejunum (scale bars 100μm). (F) Histomorphometry quantified 50±7.4% and 44±6.6% epithelialization in injured and in vivo recovered tissues, respectively, versus 100% epithelialization of controls (n = 5–7, n.s. = not significant, **P<0.01, unpaired t-test).
Reference
- 1. Ziegler AL, Pridgen TA, Mills JK, Gonzalez LM, Van Landeghem L, Odle J, et al. (2018) Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair. PLoS ONE 13(8): e0200674. https://doi.org/10.1371/journal.pone.0200674 pmid:30138372
Citation: Ziegler AL, Pridgen TA, Mills JK, Gonzalez LM, Van Landeghem L, Odle J, et al. (2019) Correction: Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair. PLoS ONE 14(2): e0212962. https://doi.org/10.1371/journal.pone.0212962
Published: February 22, 2019
Copyright: © 2019 Ziegler et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.