Figures
A portion of the caption for Fig 5 is incorrectly duplicated within the Fig 6 caption. Additionally, the *, #, and † symbols are incorrectly assigned within the captions of Figs 5, 6, 7 and 8. Please see the corrected captions here.
The Ad-GFP- or Ad-HGF- transduced myoblasts were implanted into the myocardium in an MI model for 7 days. The protein levels of HGF (a) and VEGF (b) in the transplanted area were determined by ELISA. (c) Western blot was performed for Bcl-2 expression in SM transduced with Ad-HGF, vector control, and cell control group. (d) The ratio of Bcl-2 to β-actin in the transplanted area was evaluated by Western blot (Fig 5a and Fig 5b: n = 6, P<0.05, *P<0.05 vs. control group; #P<0.05 vs. SM group; †P<0.05 vs. SM-GFP group. Fig 5d: n = 6, P<0.05, *P<0.05 vs. SM group; #P<0.05 vs. SM-GFP group).
The Ad-GFP or Ad-HGF transduced myoblasts were implanted into the myocardium in an MI model for 28 days. The cardiac functional parameters including LVSP (a) and +dp/dtmax (b), LVEDP (c), and dp/dtmin (d) were detected (n = 6, P<0.05, *P<0.05 vs. control group; #P<0.05 vs. SM group; †P<0.05 vs. SM-GFP group).
The Ad-GFP- or Ad-HGF-transduced myoblasts were implanted into the myocardium in an MI model for 28 days. (a) Representative images of histological sections in left ventricular stained with HE. Scale bars, 1 mm. (b) Images show that Sirius Red stained the cardiac sections from SM-GFP, SM only, SM-HGF group, and sham group, respectively. (c) The collagen volume fraction of SM-HGF group compared to the control group and SM group (n = 6, P<0.05, *P<0.05 vs. control group; #P<0.05 vs. SM group; †P<0.05 vs. SM-GFP group).
The Ad-GFP- or Ad-HGF-transduced myoblasts were implanted into the myocardium in an MI model for 28 days. (a) Sections were stained with antibodies against Factor VIII to facilitate the counting of vessels. The representative images of the capillary density in transplanted area were shown. (b) The numbers of vascular densities of groups indicated (n = 6, P<0.05, *P<0.05 vs. control group; #P<0.05 vs. SM group; †P<0.05 vs. SM-GFP group).
Reference
- 1. Rong S-L, Wang X-L, Zhang C-Y, Song Z-H, Cui L-H, He X-F, et al. (2017) Transplantation of HGF gene-engineered skeletal myoblasts improve infarction recovery in a rat myocardial ischemia model. PLoS ONE 12(5): e0175807. https://doi.org/10.1371/journal.pone.0175807 pmid:28459804
Citation: Rong S-L, Wang X-L, Zhang C-Y, Song Z-H, Cui L-H, He X-F, et al. (2018) Correction: Transplantation of HGF gene-engineered skeletal myoblasts improve infarction recovery in a rat myocardial ischemia model. PLoS ONE 13(4): e0196413. https://doi.org/10.1371/journal.pone.0196413
Published: April 19, 2018
Copyright: © 2018 Rong et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.