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Open Access

Correction

Correction: Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1

  • Alfred L. Yergey,
  • Paul S. Blank,
  • Stephanie M. Cologna,
  • Peter S. Backlund,
  • Forbes D. Porter,
  • Allan J. Darling
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The Competing Interest statement for this paper is incorrect. The correct statement is: Dr. Allan Darling was involved previously in additional research and testing on HPBCDs with a third party company. This related, unpublished work was performed under a commercial contract for which a confidentiality agreement prevents disclosure of the research details as well as the company and related product names. The authors confirm that this related HPBCD work by Dr. Darling was fully independent from the work published in the PLOS ONE article.

The Data Availability statement for this paper is incorrect. The correct statement is: All relevant data underlying this study are available from Zenodo (https://zenodo.org/record/573845#.Wh9DtkqnGUm).

The caption for Fig 5 is incorrect. Please see the complete, correct Fig 5 caption here.

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Fig 5. Fraction of dimers as a function of the degree of substitution.

Fractional intensity of homodimer ions, relative to total hydroxypropyl-beta-cyclodextrin (HPβCD) ion signal, plotted as a function of the degree of substitution (A); fractional intensity of heterodimer ions, relative to total HPβCD ion signal, plotted as a function of the degree of substitution (B). The fractional intensity of ions as heterodimers and homodimers is greater with Trappsol Cyclo (red circles) than with VTS-270 (green triangles). The points represent the mean value ± standard deviation of 4 replicate measurements of each material.

https://doi.org/10.1371/journal.pone.0192424.g001

Reference

  1. 1. Yergey AL, Blank PS, Cologna SM, Backlund PS, Porter FD, Darling AJ (2017) Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. PLoS ONE 12(4): e0175478. https://doi.org/10.1371/journal.pone.0175478 pmid:28414792

Citation: Yergey AL, Blank PS, Cologna SM, Backlund PS, Porter FD, Darling AJ (2018) Correction: Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. PLoS ONE 13(2): e0192424. https://doi.org/10.1371/journal.pone.0192424

Published: February 1, 2018

Copyright: © 2018 Yergey et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.