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Correction: Feasibility of assessing bone matrix and mineral properties in vivo by combined solid-state 1H and 31P MRI

  • Xia Zhao,
  • Hee Kwon Song,
  • Alan C. Seifert,
  • Cheng Li,
  • Felix W. Wehrli

The authors note that the volume used in computing the phosphorus concentration of the calibration samples was incorrect, which subsequently affected the computed in vivo phosphorus concentrations.

In Fig 5, the range of the color bar for [31P] (mol/L) is incorrect. Please see the corrected Fig 5 here.

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Fig 5. Bone water and phosphorus color maps in five of the ten study subjects.

Differences in the distribution of both bone water and 31P are visually apparent across subjects. 31P maps were interpolated to match the resolution of the proton images.

https://doi.org/10.1371/journal.pone.0192186.g001

In Fig 6, the bone phosphorus concentration values are incorrect. Please see the corrected Fig 6 here.

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Fig 6. Comparison of BMCs estimated using MRI and HR-pQCT.

BMC based on MRI-derived total 31P content plotted against HR-pQCT derived BMC for a 1-cm thick slab of tissue for nine subjects (only nine of the subjects could be scanned because the scanner was unable to accommodate the limb size of one subject). For HR-pQCT, BMC was computed by multiplying the reported vBMD with the volume of a 1-cm slab. The fitted line was obtained after excluding the 62 y/o female subject with abnormally high MRI-derived 31P concentration (red arrow).

https://doi.org/10.1371/journal.pone.0192186.g002

In Table 1, the values in the column “31P (mol/L)” are incorrect. Please see the corrected Table 1 here.

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Table 1. Bone water, porosity and phosphorus quantification results for all ten subjects.

https://doi.org/10.1371/journal.pone.0192186.t001

In Table 2, the “31P” Measurements in the “F/29”, “M/32”, and “M/48” sections are incorrect. Please see the corrected Table 2 here.

Reference

  1. 1. Zhao X, Song HK, Seifert AC, Li C, Wehrli FW (2017) Feasibility of assessing bone matrix and mineral properties in vivo by combined solid-state 1H and 31P MRI. PLoS ONE 12(3): e0173995. https://doi.org/10.1371/journal.pone.0173995 pmid:28296979