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Correction: Functional implications of hexameric assembly of RraA proteins from Vibrio vulnificus

  • Saemee Song,
  • Seokho Hong,
  • Jinyang Jang,
  • Ji-Hyun Yeom,
  • Nohra Park,
  • Jaejin Lee,
  • Yeri Lim,
  • Jun-Yeong Jeon,
  • Hyung-Kyoon Choi,
  • Minho Lee,
  • Nam-Chul Ha,
  • Kangseok Lee

The images for Figs 4 and 5 are incorrectly switched. The image that appears as Fig 4 should be Fig 5, and the image that appears as Fig 5 should be Fig 4. The figure captions appear in the correct order. Please see the corrected Fig 4 and Fig 5 below.

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Fig 4. Interactions of VvRNase E with VvRraA proteins.

Hexahistidine-tagged VvRraA1, VvRraA1-C9D, VvRraA2, VvRraA2-C9D, and the GST-fused VvRne (612–816 residues) were expressed and purified as described in the Methods section. The GST-fused VvRne protein was bound to GSH resin and incubated with VvRraA proteins and their C9D mutant proteins. Then, the proteins were eluted and the fractions were analyzed using SDS-PAGE. The protein bands were stained with Coomassie blue. Only VvRraA1 could tightly bind to VvRne.

https://doi.org/10.1371/journal.pone.0191775.g001

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Fig 5. Inhibition of VvRraA1 and VvRraA1-C9D on the cleavage of p-BR10+hpT by VvRNase E in vitro.

0.5 pmol of 5’-end-labeled p-BR10+hpT RNA was incubated with 1 pmol of VvRne with varying concentrations of VvRraA1 and VvRraA1-C9D, 50 pmol of VvRraA1, or 50 pmol of BSA in 20 μl of 1 × cleavage buffer at 37°C for 2 h for VvRne, VvRraA1 only, or BSA only controls. Samples were mixed with an equal volume of loading buffer, and then denatured at 65°C for 5 min and loaded onto a 12% polyacrylamide gel containing 8 M urea. The percentage of uncleaved p-BR10+hpT in the gel was quantitated using a phosphorimager and OptiQuant software.

https://doi.org/10.1371/journal.pone.0191775.g002

Reference

  1. 1. Song S, Hong S, Jang J, Yeom J- H, Park N, Lee J, et al. (2017) Functional implications of hexameric assembly of RraA proteins from Vibrio vulnificus. PLoS ONE 12(12): e0190064. https://doi.org/10.1371/journal.pone.0190064 pmid:29261778