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Open Access

Correction

Correction: Procollagen C-Proteinase Enhancer 1 (PCPE-1) as a Plasma Marker of Muscle and Liver Fibrosis in Mice

  • Eyal Hassoun,
  • Mary Safrin,
  • Hana Ziv,
  • Sarah Pri-Chen,
  • Efrat Kessler

Fig 2 is incomplete as Panel C is missing. The authors have provided the complete Fig 2 here.

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Fig 2. Diaphragms from mdx mice show increased collagen type I and PCPE-1 levels (A,B) and both are co-localized in the diaphragm tissue (C).

(A) Sirius red staining of diaphragm sections from 4 and 8.5 months old mdx mice and age-matched C57/BL/6 (control, wt) (one mouse per group). Red, collagen; Green, non-collagenous proteins. (B) Immunoblot showing increased amounts of collagen type I and PCPE-1 in protein extracts of diaphragms from mdx mice relatively to corresponding wild type (wt) controls (one mouse per group). The amounts of protein applied on each lane were 1 and 25 μg for collagen type I and PCPE-1 detection, respectively. α1 (I), alpha 1 chain of type I collagen. kDa, kilo Dalton. (C) Immunofluorescence analysis for type I collagen and PCPE-1 in diaphragms from a four months old C57/BL/6 (wt) and an aged matched mdx mouse. Collagen type I (red) was detected using Rhodamine-conjugated secondary antibody and PCPE-1 (green) was visualized using a Cy2-conjugated secondary antibody. Light emission was examined at 488 and 580 nm for Rhodamine and Cy2, respectively. Results displayed in each panel are from a representative randomly selected mouse from each group.

https://doi.org/10.1371/journal.pone.0162747.g001

Reference

  1. 1. Hassoun E, Safrin M, Ziv H, Pri-Chen S, Kessler E (2016) Procollagen C-Proteinase Enhancer 1 (PCPE-1) as a Plasma Marker of Muscle and Liver Fibrosis in Mice. PLoS ONE 11(7): e0159606. pmid:27458976

Citation: Hassoun E, Safrin M, Ziv H, Pri-Chen S, Kessler E (2016) Correction: Procollagen C-Proteinase Enhancer 1 (PCPE-1) as a Plasma Marker of Muscle and Liver Fibrosis in Mice. PLoS ONE 11(9): e0162747. https://doi.org/10.1371/journal.pone.0162747

Published: September 6, 2016

Copyright: © 2016 Hassoun et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.