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Correction: Nitro-Arachidonic Acid Prevents Angiotensin II Induced Mitochondrial Dysfunction in Kidney Proximal Tubular Cells

  • Beatriz Sánchez-Calvo,
  • Adriana Cassina,
  • Natalia Rios,
  • Gonzalo Peluffo,
  • José Boggia,
  • Rafael Radi,
  • Homero Rubbo,
  • Andrés Trostchansky

The following information is missing from the funding section: This work was supported by grants from Fondo Clemente Estable-ANII (FCE_6353) to AT and (FCE_6363) to GP, CSIC-Grupos (Uruguay) to HR and RR. BSC was supported by a postdoctoral fellowship by ANII-Uruguay. NR was partially supported by a fellowship from Sistema Nacional de Becas-ANII.

In Panel B of Fig 1, the x-axis is missing. Please see the corrected Fig 1 here.

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Fig 1. ANG II-mediatedO2.-production is inhibited by NO2-AA.

(A) Dehydroethydium (DHE) oxidation as an index of O2.- production in ANG II-stimulated HK-2 cells (1x106 cells) was determined by HPLC with fluorescence detection (λem = 595 nm, λexc = 510 nm). Cells were preincubated 30 min with vehicle, 10 μM NO2-AA or 10 μM AA and then exposed to DHE in simultaneous with 0.1 μM ANG II for 3 h. Quantitative analysis, expressed as the mean fold change than control condition without ANG II stimulation ± SEM, n = 3 of 2-OH-Et+ (B) and Et+ (C) are shown. *, # correspond to significant data relative to control and ANG II-treated cells, respectively (p<0.05).

https://doi.org/10.1371/journal.pone.0154651.g001

Reference

  1. 1. Sánchez-Calvo B, Cassina A, Rios N, Peluffo G, Boggia J, Radi R, et al. (2016) NitroArachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells. PLoS ONE 11(3): e0150459. pmid:26943326