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Correction: Long-Term Mild, rather than Intense, Exercise Enhances Adult Hippocampal Neurogenesis and Greatly Changes the Transcriptomic Profile of the Hippocampus

  • Koshiro Inoue,
  • Masahiro Okamoto,
  • Junko Shibato,
  • Min Chul Lee,
  • Takashi Matsui,
  • Randeep Rakwal,
  • Hideaki Soya

There are errors in Fig 3 pertaining to the number of genes identified by microarray. The authors have provided a corrected version here.

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Fig 3. Venn diagram of differentially expressed genes in each condition.

The total number of genes modified by ME (gray circles) and IE (white circles) (A), or up- (B) and down- (C) regulated genes in each condition are shown as Venn diagrams. The number in each circle indicates the selection of genes from the total microarray datasets within a defined fold range of greater than 1.5-fold and less than 0.75-fold versus sedentary (CONT).

https://doi.org/10.1371/journal.pone.0133089.g001

In the “Overview of the hippocampal transcriptome” subsection of the Results, the third sentence should read: Accordingly, 574 (up-regulated (up): 306, down-regulated (down): 268) and 385 (up: 163, down: 222) genes were specific to ME and IE, respectively (Fig 3B and 3C).

Reference

  1. 1. Inoue K, Okamoto M, Shibato J, Lee MC, Matsui T, Rakwal R, et al. (2015) Long-Term Mild, rather than Intense, Exercise Enhances Adult Hippocampal Neurogenesis and Greatly Changes the Transcriptomic Profile of the Hippocampus. PLoS ONE 10(6): e0128720. pmid:26061528