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Open Access

Correction

Correction: Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells

  • Seung Ah Choi,
  • Ji Yeoun Lee,
  • Sung Eun Kwon,
  • Kyu-Chang Wang,
  • Ji Hoon Phi,
  • Jung Won Choi,
  • Xiong Jin,
  • Ja Yun Lim,
  • Hyunggee Kim,
  • Seung-Ki Kim

The beta actin band in Fig 5B incorrectly appears as a duplicate of the beta actin band in Fig 5A. The authors have provided a corrected version of Fig 5 here, and the raw, uncropped blots are provided as Supporting Information.

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Fig 5. Cyto-chemokine ligand protein expression in brain tumor-initiating cells (BTICs) after co-culture with human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) or HFF1 cells.

Western blot analysis shows the increased expression of SDF-1 and decreased expression of IL-8 in all BTICs co-cultured with hAT-MSCs. (A and B) In medulloblastoma-BTICs and atypical teratoid/rhabdoid tumors (AT/RT)-BTICs, the expression of RANTES is increased, but that of IL-8 is not changed. (C) In glioblastoma-BTICs co-cultured with hAT-MSCs, the expression of IGF-1 is higher but that of IL-6 is lower. All data are representative of three independent experiments.

https://doi.org/10.1371/journal.pone.0132877.g001

Supporting Information

S1 File. Raw, uncropped blots for Fig 5.

Cyto-chemokine ligand protein expression in brain tumor-initiating cells (BTICs) after co-culture with human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) or HFF1 cells. β-actin was used as protein loading control. The edges of membrane and size (kDa) were marked in blot. The proteins were loaded the marker (M), only BTICs (Control: C), BTICs co-cultured with HFF1 (H), BTICs co-cultured with hAT-MSCs (A) in the order named. In medulloblastoma-BTICs and atypical teratoid/rhabdoid tumors (AT/RT)-BTICs, the blots were arranged in β-actin, SDF-1, IL-8, IL-6 and RANTES. In glioblastoma-BTICs, the blots were arranged in β-actin, SDF-1, IL-8, IGF-1 and IL-6. The patterns of protein expression were the increased expression of SDF-1 and decreased expression of IL-8 in all BTICs co-cultured with hAT-MSCs. In medulloblastoma-BTICs and AT/RT-BTICs, the expression of RANTES is increased, but that of IL-8 is not changed. In glioblastoma-BTICs co-cultured with hAT-MSCs, the expression of IGF-1 is higher but that of IL-6 is lower.

https://doi.org/10.1371/journal.pone.0132877.s001

(DOCX)

Reference

  1. 1. Choi SA, Lee JY, Kwon SE, Wang K-C, Phi JH, Choi JW, et al. (2015) Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells. PLoS ONE 10(6): e0129292. pmid:26076490

Citation: Choi SA, Lee JY, Kwon SE, Wang K-C, Phi JH, Choi JW, et al. (2015) Correction: Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells. PLoS ONE 10(7): e0132877. https://doi.org/10.1371/journal.pone.0132877

Published: July 28, 2015

Copyright: © 2015 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited