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Open Access

Correction

Correction: Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse

  • The PLOS ONE Staff

There is an error in the last sentence of the “Mice” subsection of the Materials and Methods. The correct sentence is: Mice were anesthetized with a lethal dose of Euthasol prior to decapitation at 4-5 weeks of age.

There is an error in the first sentence of the “Preparation of Mouse Brain Extracts” subsection of the Materials and Methods. The correct sentence is: Mouse brains were weighed immediately after removal and suspended in 9 vol of ice-cold homogenization buffer (10% (w/v) sucrose, 5 mM K-Hepes, pH 7.6, 0.5 mM EDTA, 0.1 mM DTT (dithiothreitol), 50 mM NaF and 1 mM Na3VO4 as phosphatase inhibitors, and 1% (v/v) mammalian protease inhibitor mixture (Sigma).

There is an error in the last sentence of the “Protein Concentration and Enzyme Activity” subsection of the Materials and Methods. The correct sentence is: One unit of CKB activity is defined here as one µmol of NADPH generated per min at 25°C under initial rate conditions.

Reference

  1. 1. Dimitrijevic A, Qin Z, Aswad DW (2014) Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse. PLoS ONE 9(6): e100622

Citation: The PLOS ONE Staff (2014) Correction: Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse. PLoS ONE 9(12): e116556. https://doi.org/10.1371/journal.pone.0116556

Published: December 22, 2014

Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.