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Correction

Correction: Aspirin Delimits Platelet Life Span by Proteasomal Inhibition

  • The PLOS ONE Staff

The lower panel Western blot in Figure 2A is incorrect. The authors have provided a corrected Figure 2 here.

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Figure 2. Study of proteosome and caspase-3 activities in aspirin-treated platelets (A), Western blots showing expression level of active Bax in platelets pretreated with ethanol, aspirin, ABT737, epoxomicin, PSI and bortezomib, as indicated (upper panel) normalized against β-actin (lower panel).

(B), Quantitative representation of active Bax levels in platelet whole cell lysates determined by densitometry of Western blots. (C), caspase-3 activity from the extent of cleavage of fluorigenic substrate AC-DEVD-AMC. (D), Assay of proteasome enzymatic activity in platelets pretreated with ethanol, PSI (proteasome inhibitor) (10 µM) and aspirin. Data are representative of five different experiments and expressed as mean±SD. (*p<0.05 as compared to ethanol-pretreated resting platelets).

https://doi.org/10.1371/journal.pone.0105049.g002

Reference

  1. 1. Nayak MK, Dash A, Singh N, Dash D (2014) Aspirin Delimits Platelet Life Span by Proteasomal Inhibition. PLoS ONE 9(8): e105049

Citation: The PLOS ONE Staff (2014) Correction: Aspirin Delimits Platelet Life Span by Proteasomal Inhibition. PLoS ONE 9(12): e115927. https://doi.org/10.1371/journal.pone.0115927

Published: December 12, 2014

Copyright: © 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.