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Correction: Trop-2 Is a Determinant of Breast Cancer Survival

  • The PLOS ONE Staff

There is an error in the third sentence of the second paragraph of the “Statistical Analysis” subsection of the Materials and Methods. The correct sentence is: The CI curves were estimated using the 1-Kaplan-Meier probability plots.

There are a number of errors in the headings for Table 2. Please see the corrected Table 2 here.

There is an error in the legend for Figure 4. Please see the corrected Figure 4 here.

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Figure 4. Impact of membrane versus intracellular Trop-2 on patient survival.

Cumulative incidence (CI) estimates of death from any cause are reported on the y-axis as a function of follow-up time for distinct Trop-2 expression sub-groups (cell membrane; mAb-detected intracellular; pAb-detected intracellular). Trop-2 expression was categorized according to (top) intensity scores (0, 1+, 2+, 3+), (middle) intensity grouping, i.e. positive scores 1–12 (+) versus score 0 (−), (bottom) percentage of stained cells (low, ≤5%; intermediate, 6–85%; high, ≥86%), as indicated in the panels.

https://doi.org/10.1371/journal.pone.0096993.g004

There is an error in the legend for Figure 5. Please see the corrected Figure 5 here.

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Figure 5. Impact of membrane versus intracellular Trop-2 on disease relapse.

Crude cumulative incidence (CCI) estimates of disease relapse are reported on the y-axis as a function of follow-up time for distinct Trop-2 expression sub-groups (cell membrane; mAb-detected intracellular; pAb-detected intracellular). Trop-2 expression was categorized according to (top) intensity scores (0, 1+, 2+, 3+), (middle) intensity grouping, i.e. positive scores 1–12 (+) versus score 0 (−), (bottom) percentage of stained cells (low, ≤5%; intermediate, 6–85%; high, ≥86%), as indicated in the panels. CCI were estimated accounting for death as a competing risk.

https://doi.org/10.1371/journal.pone.0096993.g005

Reference

  1. 1. Ambrogi F, Fornili M, Boracchi P, Trerotola M, Relli V, et al. (2014) Trop-2 Is a Determinant of Breast Cancer Survival. PLoS ONE 9(5): e96993