The legend of Figure 4 should read: "Figure shows proportion of attacks treated before and after each timepoint. n = 72 for HCP-administered attacks, n = 158 for self-administered attacks. All attacks are included at each timepoint; *** p=0.001 for self-administration versus HCP-administration, *p=0.016 for self-administration versus HCP-administration, NS, not significant; HCP, healthcare professional; SA, self-administration"

The first line of the "Statistical Analyses" subsection should read "To test the hypothesis that early administration of icatibant is associated with reduced attack duration, the total duration of the attack was compared for attacks treated <1 hour versus ≥1 hour, <2 hours versus ≥2 hours, and <5 hours versus ≥5 hours of attack onset."

The following text should be added to the end of the Acknowledgement section: "The authors would also like to thank the IOS investigators for their contributions: Denmark: Bygum A; France: Blanchard Delauny C, Coppere B, Fain O, Gompel A, Guez S, Jeandel P, Launay D, Maillard H, Martin L, Masseau A, Ollivier Y; Germany: Bas M, Bauer M, Bork K, Greve J; Greece: Psarros F; Israel: Graif Y, Kivity S, Toubi E; Italy: Cillari E, Montinaro V, Triggiani M; Spain: Gala G, Guilarte L, Hernandez D, Hernando de Larramnedi C, Lleonart R, Lobera T, Baeza ML, Marques L; Sweden: Bjoerkander J; UK: Helbert M."

The correct version of Figure 4 is available here:

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