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Correction: Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

  • Jeremy Sokolove,
  • Reuven Bromberg,
  • Kevin D. Deane,
  • Lauren J. Lahey,
  • Lezlie A. Derber,
  • Piyanka E. Chandra,
  • Jess D. Edison,
  • William R. Gilliland,
  • Robert J. Tibshirani,
  • Jill M. Norris,
  • V. Michael Holers,
  • William H. Robinson

The affiliations for the fourth and sixth authors were incorrect. Lauren J. Lahey and Piyanka E. Chandra are not affiliated with 1 and 2, but 1 and 4. There was an error in the legend for Figure 3. The correct legend for Figure 3 is: Multiple logistic regression was performed to identify markers from the reduced set of 21 antibodies and 38 cytokines which could classify pre-clinical RA subjects as being within 2 years of the onset of clinical RA. 5-fold cross validation was performed and common markers selected for final validation. A, Demonstrated is a receiver operating characteristic (ROC) curve using the panel of markers listed in figure 3a and b. B-C, Mean and standard deviation of values for each individual autoantibody (B) or cytokine (C) contributing to prediction of imminent onset RA as measured among controls, those RA patients at a timepoint greater than 2 years prior to RA onset, or those within 2 years of clinical RA onset.