Peer Review History
| Original SubmissionNovember 18, 2025 |
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Dear Dr. Yan, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Mar 06 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.
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Kind regards, Kaywan Othman Ahmed Academic Editor PLOS One Journal Requirements: When submitting your revision, we need you to address these additional requirements. 1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and 2. Please note that PLOS One has specific guidelines on code sharing for submissions in which author-generated code underpins the findings in the manuscript. In these cases, we expect all author-generated code to be made available without restrictions upon publication of the work. Please review our guidelines at https://journals.plos.org/plosone/s/materials-and-software-sharing#loc-sharing-code and ensure that your code is shared in a way that follows best practice and facilitates reproducibility and reuse. 3. 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Authors must share the “minimal data set” for their submission. PLOS defines the minimal data set to consist of the data required to replicate all study findings reported in the article, as well as related metadata and methods (https://journals.plos.org/plosone/s/data-availability#loc-minimal-data-set-definition). For example, authors should submit the following data: - The values behind the means, standard deviations and other measures reported; - The values used to build graphs; - The points extracted from images for analysis. Authors do not need to submit their entire data set if only a portion of the data was used in the reported study. If your submission does not contain these data, please either upload them as Supporting Information files or deposit them to a stable, public repository and provide us with the relevant URLs, DOIs, or accession numbers. For a list of recommended repositories, please see https://journals.plos.org/plosone/s/recommended-repositories. If there are ethical or legal restrictions on sharing a de-identified data set, please explain them in detail (e.g., data contain potentially sensitive information, data are owned by a third-party organization, etc.) and who has imposed them (e.g., an ethics committee). Please also provide contact information for a data access committee, ethics committee, or other institutional body to which data requests may be sent. If data are owned by a third party, please indicate how others may request data access. 5. We note you have included a table to which you do not refer in the text of your manuscript. Please ensure that you refer to Table 4 & 5 in your text; if accepted, production will need this reference to link the reader to the Table 6. If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. Is the manuscript technically sound, and do the data support the conclusions? Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes Reviewer #4: Yes Reviewer #5: Yes ********** 2. Has the statistical analysis been performed appropriately and rigorously? -->?> Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: No Reviewer #4: No Reviewer #5: N/A ********** 3. Have the authors made all data underlying the findings in their manuscript fully available??> The PLOS Data policy Reviewer #1: No Reviewer #2: Yes Reviewer #3: Yes Reviewer #4: No Reviewer #5: Yes ********** 4. Is the manuscript presented in an intelligible fashion and written in standard English??> Reviewer #1: No Reviewer #2: Yes Reviewer #3: Yes Reviewer #4: No Reviewer #5: Yes ********** Reviewer #1: Review Comments to the Author for Consideration The manuscript reflects a strong level of technical depth; however, several aspects of presentation, structure, and methodological clarity would benefit from improvement to enhance readability, transparency, and overall academic quality. The manuscript would benefit from a more explicitly defined problem statement. While the need for the research can be inferred, the authors should clearly articulate the problem being addressed, including not only the algorithmic improvement but also the rationale for its application to the selected dataset and practical use case. The opening sentence of the introduction, “When strong learners are difficult to learn directly in machine learning, Boosting provides an effective design framework for ensemble learning,” should be revised. As the first sentence of an academic manuscript, it should reflect a more polished scholarly tone, avoid awkward phrasing, and clearly establish context with sufficient technical depth. In addition, the introductory paragraph would benefit from improved logical flow and cohesion, as statements such as “AdaBoost has good generalization ability and is not prone to overfitting” appear somewhat isolated without clearer linkage to preceding sentences. The repeated use of the phrase “In practical applications” throughout the introduction is stylistically repetitive and should be reviewed. Similarly, the frequent use of “the AdaBoost” is, in many instances, grammatically unnecessary and overly repetitive and should be corrected to align with standard academic usage. In the sentence “This mechanism forces subsequent weak classifiers to overly focus on noisy samples, thereby seriously reducing the learning performance of the model,” the expressions “overly focus” and “seriously reducing” appear subjective and insufficiently objective for academic writing. More measured and precise phrasing is recommended. In addition, multiple instances of “[Error! Reference source not found.]” should be corrected. The paragraph outlining the paper structure (e.g., “The structure of this paper is as follows…”) does not appear necessary in the introduction of an academic research article and should be reviewed, particularly if not required by the journal’s formatting guidelines. The authors should consider reorganising the overall manuscript structure and adopting more professional and standardised chapter or section headings. In particular, clearer separation between the background, the proposed methodology, theoretical analysis, experimental evaluation, results, and conclusion would significantly improve readability and accessibility for a broad audience. From a methodological perspective, the authors should clarify whether alternative feature selection algorithms were considered and provide a brief justification for the selection of the Boruta algorithm, including the criteria or comparative considerations that informed this choice. The authors should also consider including the URL link to the Statlog dataset utilised and provide an overview of the dataset background, including a clear rationale for its selection in the context of the study. The presentation of the evaluation results would benefit from improvement. Specifically, the authors should consider utilising a consistent table orientation aligned with the main text, as the current presentation disrupts readability and makes comparison of results less intuitive. In addition, figures directly supporting the reported results should be presented within the relevant results or discussion sections, rather than being indexed at the later end of the manuscript, as this would improve interpretability and allow readers to more easily relate visual evidence to the accompanying analysis. The concluding recommendations "Furthermore, based on the research findings, recommendations for the prevention of cardiovascular diseases ... early intervention and reducing the risk of disease onset" should be strengthened by explicitly anchoring them to the model outputs and feature-level evidence derived from the analysis. Finally, the authors should note that the abstract should also reflect these improvements, such that it effectively conveys its intended purpose of providing a comprehensive and coherent overview of the study. Overall, the study reflects strong technical depth but would significantly benefit from the improvements outlined above. Good work to the authors, and good luck! Reviewer #2: This paper presents a novel method to improve the performance of AdaBoost in environments with noisy and imbalanced data. The paper claims novelty in improving AdaBoost; however, the authors should compare their proposed method with two similar studies listed below: 1. A noise-detection based AdaBoost algorithm for mislabeled data 2. Bounded exponential loss function based AdaBoost ensemble of OCSVMs If the proposed method is similar to those presented in the two above-mentioned articles, the authors should clearly explain the similarities and differences. In addition, the experimental results section should be improved. For example, the authors should describe the dataset in detail and explain the nature of the noise and class imbalance present in the data. To further improve the clarity of the paper, the authors are encouraged to review the two above-mentioned articles and follow their presentation structure. The results should be presented using figures and charts to enhance clarity. Furthermore, the quality of the figures should be improved. Reviewer #3: This paper proposes a Smooth Bounded Exponential Loss–based AdaBoost method for classification on noisy and imbalanced datasets. The proposed method extends the standard AdaBoost algorithm by introducing a parameter, “theta,” into the classifier weight calculation. While the idea is potentially interesting, the current manuscript requires substantial revisions before it can be considered for publication. In particular, the paper lacks a clear and well-structured explanation of the theoretical motivation behind the proposed loss function and weighting mechanism. Moreover, the experimental evaluation and result analysis are not sufficiently comprehensive to fully support the claimed improvements over existing methods. Addressing these issues would significantly improve the clarity, rigor, and overall quality of the paper. The following points detail my major concerns: 1. The proposed ASWBoost incorporates the parameter “theta” into the classifier weight calculation, as presented in Equations (2), (4), and (5). The authors have provided the general motivation and mechanism of using theta to control classifier weights. However, it would be beneficial to include a more intuitive explanation of how theta in Equations (2), (4), and (5) affects the smoothness of both classifier weights and sample weights. Such an explanation would help readers better understand the technical role of theta and how it influences the learning process. 2. The authors have presented all the required equations for ASWBoost in the manuscript. Therefore, I suggest simplifying the notation in Algorithm 1 by removing the explicit equations and instead referring to the corresponding equations introduced earlier in the paper. Repeating the same equations within the algorithm is unnecessary and may reduce clarity. In addition, it is unclear whether Equations (8) and (9) are part of the ASWBoost procedure described in Algorithm 1. If they are, Algorithm 1 should be revised accordingly to explicitly include these equations. 3. The proposed method has been evaluated extensively using synthetic datasets with varying sample sizes and noise levels. However, the study lacks evaluation on real-world datasets, particularly publicly available benchmark datasets commonly used in class imbalance classification research. Real-world datasets often exhibit more complex characteristics, such as irregular data distributions, uncorrelated or redundant features, high dimensionality, severe class overlap, and the presence of small disjuncts. In my view, evaluating the proposed method solely on synthetic datasets is not sufficient when many public benchmark datasets are readily available. Therefore, I strongly recommend that the authors consider evaluating their method on real-world benchmark datasets and refer to the following relevant studies: a. Azal Ahmad Khan, Omkar Chaudhari, Rohitash Chandra, “A review of ensemble learning and data augmentation models for class imbalanced problems: Combination, implementation and evaluation,” Expert Systems with Applications, Volume 244, 2024. https://doi.org/10.1016/j.eswa.2023.122778. b. Fachrie, M., Musdholifah, A., and Pulungan, R., “Effectiveness of data resampling and ensemble learning in multiclass imbalance learning,” Artificial Intelligence Review, Volume 58, 368 (2025). https://doi.org/10.1007/s10462-025-11357-w 4. Since the paper focuses on handling class imbalance, I recommend evaluating the classification performance of ASWBoost using metrics that are more appropriate for imbalanced learning, such as Average Accuracy (AvAcc), Geometric Mean (G-mean), macro F1-score, and AUC. Metrics such as accuracy, precision, recall, and standard F1-score are often misleading in imbalanced classification settings. Please also provide clear and correct mathematical definitions for all evaluation metrics used in this study. 5. As theta is the key parameter that plays a significant role in ASWBoost, it is necessary to provide an in-depth analysis of how different values of theta influence classification performance. I suggest conducting additional experiments using a range of theta values and presenting a comprehensive analysis of the relationship between theta and the performance of ASWBoost. 6. Please include appropriate statistical significance analysis, for example, using the Friedman test followed by a Nemenyi post-hoc test, to assess whether the performance differences between ASWBoost and other boosting algorithms are statistically significant. 7. Several entries in Tables 2, 3, and 4 are confusing, particularly the terms “200 datasets,” “3000 datasets,” and “10000 datasets.” It is unclear how experiments could be conducted using such a large number of datasets. I assume that the authors actually mean “200 instances,” “3000 instances,” and “10000 instances.” Please revise these tables to provide clear and accurate information. 8. Several citations in the manuscript are not properly recognized or formatted. Please carefully review and correct all references to ensure accuracy and consistency. 9. Finally, the conclusion should clearly discuss the limitations of the proposed method. As no method is without limitations, this discussion is essential for providing a balanced perspective. In addition, please outline potential directions for future work that could help other researchers extend or improve upon the current study. Reviewer #4: The manuscript presents a modified AdaBoost variant (ASWBoost) using a smooth bounded exponential loss to improve robustness against noise and class imbalance. The topic is relevant and suitable for high impact factor journal, and the idea of controlling sample weight updates with a tunable parameter is meaningful. However, the paper currently suffers from mathematical inconsistencies, unclear derivations, missing experimental details, depth discuss of the experimental result, formatting errors, and insufficient comparison rigor, which must be addressed before the work can be considered for publication. Reviewer #5: The paper discussed the enhanced version of AdaBoost that efficiently leverages imbalanced and noisy data. The author utilized real-world and benchmark datasets to prove their algorithm’s performance, which outperforms AdaBoost. ********** what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy Reviewer #1: Yes: Adefemi Lawrence Ayodele Reviewer #2: Yes: Mohammad Khanbabaei Reviewer #3: No Reviewer #4: No Reviewer #5: No ********** [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation. NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.
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| Revision 1 |
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Dear Dr. Yan, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Aug 06 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.
If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter. If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols. As the corresponding author, your ORCID iD is verified in the submission system and will appear in the published article. PLOS supports the use of ORCID, and we encourage all coauthors to register for an ORCID iD and use it as well. Please encourage your coauthors to verify their ORCID iD within the submission system before final acceptance, as unverified ORCID iDs will not appear in the published article. Only the individual author can complete the verification step; PLOS staff cannot verify ORCID iDs on behalf of authors. We look forward to receiving your revised manuscript. Kind regards, Kaywan Othman Ahmed Academic Editor PLOS One Journal Requirements: If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author Reviewer #1: All comments have been addressed Reviewer #2: (No Response) Reviewer #3: (No Response) Reviewer #5: All comments have been addressed Reviewer #6: All comments have been addressed ********** 2. Is the manuscript technically sound, and do the data support the conclusions??> Reviewer #1: Yes Reviewer #2: Partly Reviewer #3: Yes Reviewer #5: Yes Reviewer #6: Yes ********** 3. Has the statistical analysis been performed appropriately and rigorously? -->?> Reviewer #1: Yes Reviewer #2: N/A Reviewer #3: No Reviewer #5: I Don't Know Reviewer #6: Yes ********** 4. Have the authors made all data underlying the findings in their manuscript fully available??> The PLOS Data policy Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes Reviewer #5: Yes Reviewer #6: Yes ********** 5. Is the manuscript presented in an intelligible fashion and written in standard English??> Reviewer #1: Yes Reviewer #2: Yes Reviewer #3: Yes Reviewer #5: Yes Reviewer #6: Yes ********** Reviewer #1: Thank you for submitting your revised manuscript. However, the two minor revisions highlighted below require attention. Funding: The Financial Disclosure field states, "The author(s) received no specific funding for this work" while the Funding section identifies Grant No. 202405AS350003. These statements are contradictory and must be reconciled before publication. Abstract: The statement "ASWBoost outperforms standard AdaBoost and other mainstream ensemble algorithms" overstates the findings. Authors should consider naming the specific ensemble algorithms over which ASWBoost demonstrates statistically significant superiority and qualify the claim accordingly. Thank you. Good luck! Reviewer #2: Dear Editor, I studied the revised manuscript, carefully. Regarding my previous comments, there is no any considerable change employed in the revised manuscript. For example, I suggested to the authors that there are two similar studies related to this manuscript. The authors should study these articles and compare their study with these articles. Therefore, I repeat the previous recommendations to enhance the quality of this manuscript as follows. This paper presents a novel method to improve the performance of AdaBoost in environments with noisy and imbalanced data. The paper claims novelty in improving AdaBoost; however, the authors should compare their proposed method with two similar studies listed below: 1. A noise-detection based AdaBoost algorithm for mislabeled data 2. Bounded exponential loss function based AdaBoost ensemble of OCSVMs If the proposed method is similar to those presented in the two above-mentioned articles, the authors should clearly explain the similarities and differences. In addition, the experimental results section should be improved. For example, the authors should describe the dataset in detail and explain the nature of the noise and class imbalance present in the data. To further improve the clarity of the paper, the authors are encouraged to review the two above-mentioned articles and follow their presentation structure. The results should be presented using figures and charts to enhance clarity. Furthermore, the quality of the figures should be improved. PLOS One is a prestigious journal and the papers published in this journal should mind the basic and essential issues required to increase the credibility of them. The authors should consider the recommendations presented by the referees due to their valuable time that they consume to read and evaluate their manuscripts. Regards. Reviewer #3: The manuscript has been substantially revised, and the current version shows a noticeable improvement in terms of organization, methodology description, and overall presentation. The authors have addressed many of the concerns raised in the previous review round. Nevertheless, several issues remain that should be considered to further improve the clarity, consistency, and completeness of the manuscript. 1. In Figure 2, the label of the x-axis appears to be incorrect. Based on the context and the experimental setup, the x-axis should be related to the level of noise interference. The authors are encouraged to verify and correct the axis description. 2. For Table 2, it would be beneficial to provide additional information regarding the datasets, including the number of classes and the number of instances in each class. Such information would help readers better understand the characteristics and imbalance level of the datasets used in the experiments. 3. The presentation of the experimental results is currently inconsistent across evaluation metrics. Specifically, G-mean scores are reported in tabular form (Table 3), whereas AUC and Balanced Accuracy are presented only through bar charts. To improve consistency and facilitate a more precise comparison among methods, it is recommended that all evaluation metrics be reported in tabular form. This would allow readers to clearly examine the exact performance values achieved by each method. 4. Since the study involves two different types of datasets, i.e. synthetic datasets and real-world datasets, it is recommended that the captions of all tables and figures explicitly indicate the dataset category to which the results correspond. This would help readers avoid potential confusion when interpreting the experimental findings. 5. The experiments conducted on synthetic datasets include Macro-F1 as one of the evaluation metrics. However, this metric is not reported in the experiments on real-world datasets. The rationale behind this inconsistency should be clarified. If Macro-F1 is considered relevant for evaluating the synthetic datasets, it would be reasonable to include it for the real-world datasets as well, unless there is a specific justification for its omission. 6. The statistical significance analysis appears to be conducted only for the G-mean metric. This practice is uncommon in the related literature, where statistical tests are generally performed for all reported evaluation metrics. The authors are encouraged to extend the statistical analysis to AUC, Balanced Accuracy, and any other reported metrics. 7. The manuscript would further benefit from reporting the average ranks obtained from the Friedman test. Average ranks provide valuable insights into the relative performance differences among competing methods and are widely used to support the interpretation of statistical comparison results. Including this information would strengthen the experimental analysis and improve the interpretability of the findings. Reviewer #5: The author has validated the proposed results using both performance and statistical metrics. Since the necessary revisions have been incorporated into the manuscript, the paper is recommended for acceptance for publication. Reviewer #6: The paper presents a genuine improvement and is suitable for publication. The theoretical derivation is now strong, the experimental section has been substantially expanded, and the statistical validation supports the claims. ********** what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy Reviewer #1: No Reviewer #2: Yes: Mohammad Khanbabaei Reviewer #3: No Reviewer #5: No Reviewer #6: No ********** [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation. NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.
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| Revision 2 |
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ASWBoost: Classification Algorithm for Noisy and Imbalanced Data Based on Parametric Exponential Loss PONE-D-25-60888R2 Dear Dr. Yan, We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements. Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication. An invoice will be generated when your article is formally accepted. Please note, if your institution has a publishing partnership with PLOS and your article meets the relevant criteria, all or part of your publication costs will be covered. Please make sure your user information is up-to-date by logging into Editorial Manager at Editorial Manager® and clicking the ‘Update My Information' link at the top of the page. For questions related to billing, please contact billing support. If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org. Kind regards, Kaywan Othman Ahmed Academic Editor PLOS One Additional Editor Comments (optional): Reviewers' comments: Reviewer's Responses to Questions Comments to the Author Reviewer #2: All comments have been addressed Reviewer #3: All comments have been addressed ********** 2. Is the manuscript technically sound, and do the data support the conclusions??> Reviewer #2: Yes Reviewer #3: Yes ********** 3. Has the statistical analysis been performed appropriately and rigorously? -->?> Reviewer #2: Yes Reviewer #3: Yes ********** 4. Have the authors made all data underlying the findings in their manuscript fully available??> The PLOS Data policy Reviewer #2: Yes Reviewer #3: Yes ********** 5. Is the manuscript presented in an intelligible fashion and written in standard English??> Reviewer #2: Yes Reviewer #3: Yes ********** Reviewer #2: (No Response) Reviewer #3: All of my comments have been addressed appropriately by the authors. Therefore, I recommend accepting the manuscript. ********** what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy Reviewer #2: Yes: Mohammad Khanbabaei Reviewer #3: No ********** |
| Formally Accepted |
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PONE-D-25-60888R2 PLOS One Dear Dr. Yan, I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS One. Congratulations! Your manuscript is now being handed over to our production team. At this stage, our production department will prepare your paper for publication. This includes ensuring the following: * All references, tables, and figures are properly cited * All relevant supporting information is included in the manuscript submission, * There are no issues that prevent the paper from being properly typeset You will receive further instructions from the production team, including instructions on how to review your proof when it is ready. Please keep in mind that we are working through a large volume of accepted articles, so please give us a few days to review your paper and let you know the next and final steps. Lastly, if your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org. You will receive an invoice from PLOS for your publication fee after your manuscript has reached the completed accept phase. If you receive an email requesting payment before acceptance or for any other service, this may be a phishing scheme. Learn how to identify phishing emails and protect your accounts at https://explore.plos.org/phishing. If we can help with anything else, please email us at customercare@plos.org. Thank you for submitting your work to PLOS One and supporting open access. Kind regards, PLOS ONE Editorial Office Staff on behalf of Dr. Kaywan Othman Ahmed Academic Editor PLOS One |
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