Peer Review History

Original SubmissionOctober 9, 2025
Decision Letter - Aloysius Gonzaga Mubuuke, Editor

Dear Dr. Emesu,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Mar 12 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org . When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

  • A letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.
  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.
  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols . Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at . Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols ..

We look forward to receiving your revised manuscript.

Kind regards,

Aloysius Gonzaga Mubuuke

Academic Editor

PLOS One

Journal Requirements:

When submitting your revision, we need you to address these additional requirements.

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and

https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf

2. In this instance it seems there may be acceptable restrictions in place that prevent the public sharing of your minimal data. However, in line with our goal of ensuring long-term data availability to all interested researchers, PLOS’ Data Policy states that authors cannot be the sole named individuals responsible for ensuring data access (http://journals.plos.org/plosone/s/data-availability#loc-acceptable-data-sharing-methods).

Data requests to a non-author institutional point of contact, such as a data access or ethics committee, helps guarantee long term stability and availability of data. Providing interested researchers with a durable point of contact ensures data will be accessible even if an author changes email addresses, institutions, or becomes unavailable to answer requests.

Before we proceed with your manuscript, please also provide non-author contact information (phone/email/hyperlink) for a data access committee, ethics committee, or other institutional body to which data requests may be sent. If no institutional body is available to respond to requests for your minimal data, please consider if there any institutional representatives who did not collaborate in the study, and are not listed as authors on the manuscript, who would be able to hold the data and respond to external requests for data access? If so, please provide their contact information (i.e., email address). Please also provide details on how you will ensure persistent or long-term data storage and availability.

3. If any figure files for review show as item type ‘other’ please change to item type ‘figure’ as the reviewer does not have access to these ’other’ files.

4. If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

5. Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments:

As you address the review comments, also proof-read the entire paper to correct language errors.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

Reviewer #2: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.-->

Reviewer #1: No

Reviewer #2: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

Reviewer #1: Dear authors thank you for submitting the manuscript. This is very well written manuscript and the employed methodology is rigor to answer the research question. To further improve the work the following are my observations and suggestions

Title: Inclusion of Urban and Rural is kind of skeptical because, it's very much known that Uganda has both. I would suggest omission of the words and consider retaining Uganda alone

Abstract

Background: While articulating the background information withe objectives, the objective should be written in past tense

Methods: It's important to state at what level was the p-value set to report significance

Results: Here the sentence "National screening utilization was 13%" sounds ectopic because this wasn't part of the objectives and hence shouldn't be reported and as the matter of fact it's reported in the UDHS report

Conclusion: You have reported that "There are stark socioeconomic and geographic inequities in cervical cancer screening in Uganda" Was this a primary goal of your research? I suggest conclusion of the key findings mirroring the study research question

Background: While it's very well written, I suggest the inclusion of the consequences of not screening for cervical cancer

Methodology:

Study design: It important to make sure that it's explicitly study design as it's observed that, there more unnecessary information included. The definition of Equity and inequity shouldn't be one this sub-section and wherever appropriately placed it's source should be cited

Description of data set: This should be rephrased to Data source where you will also need to include sampling procedures undertaken

Exploration of dataset: This subsection should be in the analysis plan

Exclusion criteria is not the opposite of the inclusion criteria please revise

Independent variables: Make sure that you have operationalize the variables by including the how they were coded in STATA and why so ?

The categorization and recategorization of the variables based on what grounds ?

Dependent variables: The word utilization and use are very much different please revisit oxford dictionary and choose the appropriate word.

Statistical Analysis: The sentence "Associations between categorical variables were assessed using chi-square tests" is not right. Refer to the book titled "Essential Medical Statistics" written by Betty Kirkwood where its clearly stated that chi-square can not assess the association but rather the distribution of independent variable to the dependent variable

RESULTS: Well written however:

As the rule of thumb do you think its not important to describe your study population as objective zero?

DISCUSSION: Its also important to discuss the implication of the results as well as comparison from other findings

Reviewer #2: This manuscript examines socioeconomic and geographic inequities in cervical cancer screening awareness and utilization among women of reproductive age in Uganda using data from the 2022 Uganda Demographic and Health Survey. The topic is highly relevant and timely, particularly in the context of the World Health Organization’s cervical cancer elimination strategy and universal health coverage commitments. The manuscript is generally intelligible and logically structured, with clearly stated objectives and an appropriate conceptual grounding in vertical equity. The authors demonstrate strong familiarity with the policy and epidemiological context and present findings that are broadly consistent with existing evidence from low- and middle-income settings. However, while the scientific intent and overall structure are sound, the manuscript requires substantial revision before it can be considered for publication. The language, although understandable, contains numerous typographical, grammatical, and stylistic errors that reduce clarity and readability. These include repeated spelling mistakes, inconsistent punctuation and spacing, overly long or fragmented sentences, and inconsistent terminology across sections. In addition, several numerical values, percentages, and denominators are reported inconsistently between the text and tables, which undermines interpretability. As PLOS ONE does not copyedit accepted manuscripts, careful language editing and harmonisation of all reported figures are essential at revision.

The study relies on secondary data from the 2022 Uganda Demographic and Health Survey, obtained with permission from the Uganda Bureau of Statistics, which is appropriate and ethically sound. However, the data availability statement should be strengthened to fully comply with PLOS ONE policy. The manuscript should explicitly state that the data are owned by a third party and are publicly accessible upon request through the DHS Program or UBOS, with clear instructions provided for access. While the authors cannot share raw data directly, they should clarify that all analyses can be replicated using the publicly available dataset. If analytic code or derived datasets were generated, the authors are encouraged to deposit these in a public repository or state that they are available upon reasonable request. The statistical approach is broadly appropriate for the research objectives and data source, and the use of descriptive statistics, chi-square tests, and concentration indices to examine socioeconomic and rural–urban inequities aligns well with the stated vertical equity framework. Nevertheless, several methodological clarifications are required. The authors should explicitly state whether sampling weights, clustering, and stratification were applied in all analyses, including inequality measures, as this is essential for nationally representative inference. Given that the primary outcomes are binary, the manuscript should specify whether a corrected concentration index (such as the Erreygers or Wagstaff correction) was used and justify the choice. Confidence intervals for key estimates, including prevalence and concentration indices, are not consistently reported and should be added. In addition, internal inconsistencies in sample sizes and percentages across sections must be resolved, and interpretation of concentration indices should be standardised with consistent use of “pro-rich” and “pro-poor” terminology.

Overall, the manuscript presents a technically sound observational analysis, and the data largely support the authors’ conclusions regarding low screening uptake and persistent inequities in cervical cancer screening awareness and utilization in Uganda. The findings clearly demonstrate that wealthier women are disproportionately advantaged in both knowledge of and access to screening services, and the discussion appropriately situates these results within broader debates on health equity and universal health coverage. The policy implications proposed, including the need for targeted awareness interventions, equity-sensitive resource allocation, and financial protection mechanisms, are reasonable and broadly supported by the data. However, the authors should strengthen the linkage between specific quantitative findings and their policy recommendations, ensure complete internal consistency across results, and avoid causal language given the cross-sectional design. There are no apparent concerns regarding dual publication, and the use of anonymized DHS data is ethically appropriate, although an explicit ethics statement confirming secondary-data approval or exemption should be included. In summary, this is a relevant and potentially valuable contribution to the literature that would be suitable for publication in PLOS ONE after major revisions addressing language quality, methodological transparency, data availability clarification, and consistency of reporting.

**********

what does this mean? ). If published, this will include your full peer review and any attached files.). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our For information about this choice, including consent withdrawal, please see our Privacy Policy .-->

Reviewer #1: No

Reviewer #2: Yes: Edward Mawejje, MD, MPH, IMPSEdward Mawejje, MD, MPH, IMPS

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures

You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation.

NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.

Revision 1

We wish to extend our sincere gratitude to both reviewers for their thoughtful, detailed, and constructive critiques of our manuscript. Your combined expertise has been invaluable in significantly strengthening this work.

Your comments collectively guided essential improvements across several key dimensions: the imperative for professional language editing and internal consistency, the need for greater methodological transparency and rigor (particularly regarding survey weights and concentration indices), and the importance of a more impactful discussion that clearly links findings to implications and policy.

We have addressed each point conscientiously. The revised manuscript now features polished language and consistent reporting, explicit methodological details compliant with best practices for complex survey analysis, and a substantially reframed discussion that directly translates specific quantitative inequities into actionable insights for cervical cancer prevention policy in Uganda.

We are confident that your guidance has transformed this into a more robust, clear, and valuable contribution to the literature. Thank you for your time and for helping to improve our research.

Attachments
Attachment
Submitted filename: Response to Reviewers.docx
Decision Letter - Aloysius Gonzaga Mubuuke, Editor

Equity in  Awareness and Utilization of Cervical Cancer Screening Services among Women of Reproductive Age in Uganda: Analysis of vertical Equity using evidence from UDHS 2022

PONE-D-25-54550R1

Dear Dr. Emesu,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice will be generated when your article is formally accepted. Please note, if your institution has a publishing partnership with PLOS and your article meets the relevant criteria, all or part of your publication costs will be covered. Please make sure your user information is up-to-date by logging into Editorial Manager at Editorial Manager®  and clicking the ‘Update My Information' link at the top of the page. For questions related to billing, please contact  and clicking the ‘Update My Information' link at the top of the page. For questions related to billing, please contact billing support ..

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Aloysius Gonzaga Mubuuke

Academic Editor

PLOS One

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #1: All comments have been addressed

Reviewer #2: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.-->

Reviewer #1: Yes

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

**********

Reviewer #1: Thank you for reviewing the manuscript. It has take it shape now and you have addressed all comments I raised and hence I recommend publication. Thank you and best wishes

Reviewer #2: Article well revized and fit for considerations nased on the revisions docuemented, well anotated and classical solutions been inserted at last.

**********

what does this mean? ). If published, this will include your full peer review and any attached files.). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our For information about this choice, including consent withdrawal, please see our Privacy Policy .-->

Reviewer #1: No

Reviewer #2: Yes: Dr Edward Mawejje, MD, MPH, IMPSDr Edward Mawejje, MD, MPH, IMPS

**********

Formally Accepted
Acceptance Letter - Aloysius Gonzaga Mubuuke, Editor

PONE-D-25-54550R1

PLOS One

Dear Dr. Emesu,

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS One. Congratulations! Your manuscript is now being handed over to our production team.

At this stage, our production department will prepare your paper for publication. This includes ensuring the following:

* All references, tables, and figures are properly cited

* All relevant supporting information is included in the manuscript submission,

* There are no issues that prevent the paper from being properly typeset

You will receive further instructions from the production team, including instructions on how to review your proof when it is ready. Please keep in mind that we are working through a large volume of accepted articles, so please give us a few days to review your paper and let you know the next and final steps.

Lastly, if your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

You will receive an invoice from PLOS for your publication fee after your manuscript has reached the completed accept phase. If you receive an email requesting payment before acceptance or for any other service, this may be a phishing scheme. Learn how to identify phishing emails and protect your accounts at https://explore.plos.org/phishing.

If we can help with anything else, please email us at customercare@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Aloysius Gonzaga Mubuuke

Academic Editor

PLOS One

Open letter on the publication of peer review reports

PLOS recognizes the benefits of transparency in the peer review process. Therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. Reviewers remain anonymous, unless they choose to reveal their names.

We encourage other journals to join us in this initiative. We hope that our action inspires the community, including researchers, research funders, and research institutions, to recognize the benefits of published peer review reports for all parts of the research system.

Learn more at ASAPbio .